| Literature DB >> 23775917 |
Zuxiao Zhang1, Fei Wang, Xin Mu, Pinhong Chen, Guosheng Liu.
Abstract
Group activity: A novel copper-catalyzed fluorination of internal allylic bromides and chlorides has been developed by using Et3N⋅3 HF as the fluorine source. A functional group (FG) within the substrate is required to achieve the allylic fluorination, and a variety of secondary allylic fluoride compounds can be accessed in good yield with excellent regioselectivity.Entities:
Keywords: allylic halides; copper catalysis; fluorination; regioselectivity; synthetic methods
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Year: 2013 PMID： 23775917 DOI： 10.1002/anie.201301891
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336