Literature DB >> 23775788

Light-regulated stapled peptides to inhibit protein-protein interactions involved in clathrin-mediated endocytosis.

Laura Nevola1, Andrés Martín-Quirós, Kay Eckelt, Núria Camarero, Sébastien Tosi, Artur Llobet, Ernest Giralt, Pau Gorostiza.   

Abstract

Control of membrane traffic: Photoswitchable inhibitors of protein-protein interactions were applied to photoregulate clathrin-mediated endocytosis (CME) in living cells. Traffic light (TL) peptides acting as "stop" and "go" signals for membrane traffic can be used to dissect the role of CME in receptor internalization and in cell growth, division, and differentiation.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  clathrin-mediated endocytosis; optopharmacology; peptides; photoswitches; protein-protein interactions

Mesh：

Substances：

Year:  2013        PMID： 23775788     DOI： 10.1002/anie.201303324

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  14 in total

1.  An allosteric modulator to control endogenous G protein-coupled receptors with light.

Authors:  Silvia Pittolo; Xavier Gómez-Santacana; Kay Eckelt; Xavier Rovira; James Dalton; Cyril Goudet; Jean-Philippe Pin; Artur Llobet; Jesús Giraldo; Amadeu Llebaria; Pau Gorostiza
Journal:  Nat Chem Biol       Date:  2014-08-31       Impact factor: 15.040

2.  EMBO conference series: Chemical Biology 2014.

Authors:  Eileen J Kennedy
Journal:  Chembiochem       Date:  2014-10-16       Impact factor: 3.164

3.  HOPPI-NMR: Hot-Peptide-Based Screening Assay for Inhibitors of Protein-Protein Interactions by NMR.

Authors:  Diego Brancaccio; Salvatore Di Maro; Linda Cerofolini; Stefano Giuntini; Marco Fragai; Claudio Luchinat; Stefano Tomassi; Antonio Limatola; Pasquale Russomanno; Francesco Merlino; Ettore Novellino; Alfonso Carotenuto
Journal:  ACS Med Chem Lett       Date:  2020-02-20       Impact factor: 4.345

Review 4.  Molecular photoswitches in aqueous environments.

Authors:  Jana Volarić; Wiktor Szymanski; Nadja A Simeth; Ben L Feringa
Journal:  Chem Soc Rev       Date:  2021-11-15       Impact factor: 54.564

5.  Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions.

Authors:  Anna Barnard; Kérya Long; Heather L Martin; Jennifer A Miles; Thomas A Edwards; Darren C Tomlinson; Andrew Macdonald; Andrew J Wilson
Journal:  Angew Chem Int Ed Engl       Date:  2015-02-04       Impact factor: 15.336

Review 6.  Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.

Authors:  Marta Pelay-Gimeno; Adrian Glas; Oliver Koch; Tom N Grossmann
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-26       Impact factor: 15.336

7.  Two-photon neuronal and astrocytic stimulation with azobenzene-based photoswitches.

Authors:  Mercè Izquierdo-Serra; Marta Gascón-Moya; Jan J Hirtz; Silvia Pittolo; Kira E Poskanzer; Èric Ferrer; Ramon Alibés; Félix Busqué; Rafael Yuste; Jordi Hernando; Pau Gorostiza
Journal:  J Am Chem Soc       Date:  2014-06-05       Impact factor: 15.419

8.  Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions.

Authors:  Anna Barnard; Kérya Long; Heather L Martin; Jennifer A Miles; Thomas A Edwards; Darren C Tomlinson; Andrew Macdonald; Andrew J Wilson
Journal:  Angew Chem Weinheim Bergstr Ger       Date:  2015-01-30

9.  Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.

Authors:  Yu Heng Lau; Yuteng Wu; Maxim Rossmann; Ban Xiong Tan; Peterson de Andrade; Yaw Sing Tan; Chandra Verma; Grahame J McKenzie; Ashok R Venkitaraman; Marko Hyvönen; David R Spring
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-02       Impact factor: 15.336

Review 10.  Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein Interactions.

Authors:  Teresa A F Cardote; Alessio Ciulli
Journal:  ChemMedChem       Date:  2015-11-13       Impact factor: 3.466
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