Literature DB >> 23774852

Role of eye's sign in patients with neuropsychiatric disorders of systemic lupus erythematosus.

Rui Wu1.   

Abstract

To investigate role of eye's sign in the patients with neuropsychiatric systemic lupus erythematosus (NPSLE). The scores of eye's sign in bulbar conjunctival microvascular changes were assessed in all patients according to our criteria. The disease activity was measured with SLE Disease Activity Index (SLEDAI) score. Anticardiolipin antibody (aCL) and hemorheology were performed in patients. The eye's sign and whole-blood viscosity were significantly higher in NPSLE patients than those in non-NPSLE patients. The eye's sign has a correlation with SLEDAI, disease duration, whole-blood viscosity, serum concentration of aCL, and no correlation with erythrocyte sedimentation rate, complement and titre of ANA (Anti-nuclear antibody). Our results suggest that eye's sign plays an important role in active NPSLE. The continuous disease activity promotes the vascular damage through an increasing blood viscosity and the eye's sign reflects well this condition. Checking the eye's sign is an useful indicator in assessment of activity or that of effectiveness in treating (NP)SLE.

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Year:  2013        PMID： 23774852     DOI： 10.1007/s00296-013-2802-4

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  8 in total

Review 1.  Blood-brain barrier disruption in multiple sclerosis.

Authors:  Alireza Minagar; J Steven Alexander
Journal:  Mult Scler       Date:  2003-12       Impact factor: 6.312

Review 2.  Molecular mimicry: anti-DNA antibodies bind microbial and nonnucleic acid self-antigens.

Authors:  J S Rice; C Kowal; B T Volpe; L A DeGiorgio; B Diamond
Journal:  Curr Top Microbiol Immunol       Date:  2005       Impact factor: 4.291

3.  Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.

Authors:  C Bombardier; D D Gladman; M B Urowitz; D Caron; C H Chang
Journal:  Arthritis Rheum       Date:  1992-06

4.  [Modernized study on eye's signs of blood-stasis syndrome].

Authors:  Rui Wu; Jian-xiang Xie; Feng-da Zhao
Journal:  Zhongguo Zhong Xi Yi Jie He Za Zhi       Date:  2011-03

Review 5.  The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes.

Authors: 
Journal:  Arthritis Rheum       Date:  1999-04

6.  The relationship between vascular wall shear stress and flow-mediated dilation: endothelial function assessed by phase-contrast magnetic resonance angiography.

Authors:  H A Silber; D A Bluemke; P Ouyang; Y P Du; W S Post; J A Lima
Journal:  J Am Coll Cardiol       Date:  2001-12       Impact factor: 24.094

7.  Neuropsychiatric lupus syndromes: relationship with antiphospholipid antibodies.

Authors:  Antonella Afeltra; Pierluigi Garzia; Anna Paola Mitterhofer; Marta Vadacca; Sara Galluzzo; Flavia Del Porto; Licia Finamore; Stefano Pascucci; Marina Gasparini; Bruno Laganà; Domenico Caccavo; Giovanni Maria Ferri; Antonio Amoroso; Ada Francia
Journal:  Neurology       Date:  2003-07-08       Impact factor: 9.910

8.  The 1982 revised criteria for the classification of systemic lupus erythematosus.

Authors:  E M Tan; A S Cohen; J F Fries; A T Masi; D J McShane; N F Rothfield; J G Schaller; N Talal; R J Winchester
Journal:  Arthritis Rheum       Date:  1982-11
  8 in total
  1 in total

1.  The Role of Conjunctival Microvasculation Combined with Echocardiography in Evaluating Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus.

Authors:  Jiangbiao Xiong; Shujiao Yu; Ren Liu; Xia Fang; Rui Wu
Journal:  Dis Markers       Date:  2021-11-26       Impact factor: 3.434
  1 in total

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