Literature DB >> 23766329

Cerebral asymmetry and language development: cause, correlate, or consequence?

Dorothy V M Bishop1.   

Abstract

In most people, language is processed predominantly by the left hemisphere of the brain, but we do not know how or why. A popular view is that developmental language disorders result from a poorly lateralized brain, but until recently, evidence has been weak and indirect. Modern neuroimaging methods have made it possible to study normal and abnormal development of lateralized function in the developing brain and have confirmed links with language and literacy impairments. However, there is little evidence that weak cerebral lateralization has common genetic origins with language and literacy impairments. Our understanding of the association between atypical language lateralization and developmental disorders may benefit if we reconceptualize the nature of cerebral asymmetry to recognize its multidimensionality and consider variation in lateralization over developmental time. Contrary to popular belief, cerebral lateralization may not be a highly heritable, stable characteristic of individuals; rather, weak lateralization may be a consequence of impaired language learning.

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Year:  2013        PMID: 23766329      PMCID: PMC4031634          DOI: 10.1126/science.1230531

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  82 in total

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4.  Early folding patterns and asymmetries of the normal human brain detected from in utero MRI.

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Journal:  Cereb Cortex       Date:  2011-05-12       Impact factor: 5.357

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Journal:  Arch Neurol       Date:  1986-10

Review 6.  Twitter evolution: converging mechanisms in birdsong and human speech.

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8.  Structural asymmetries in the infant language and sensori-motor networks.

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Journal:  Cereb Cortex       Date:  2008-06-17       Impact factor: 5.357

9.  CNTNAP2 variants affect early language development in the general population.

Authors:  A J O Whitehouse; D V M Bishop; Q W Ang; C E Pennell; S E Fisher
Journal:  Genes Brain Behav       Date:  2011-03-01       Impact factor: 3.449

10.  Cerebral dominance for language function in adults with specific language impairment or autism.

Authors:  Andrew J O Whitehouse; Dorothy V M Bishop
Journal:  Brain       Date:  2008-10-25       Impact factor: 13.501

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  107 in total

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Journal:  Hum Brain Mapp       Date:  2015-12-23       Impact factor: 5.038

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3.  Genome-wide association study of handedness excludes simple genetic models.

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Journal:  Heredity (Edinb)       Date:  2013-09-25       Impact factor: 3.821

4.  Ultrasonic vocalization changes and FOXP2 expression after experimental stroke.

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5.  A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer's Disease.

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Journal:  Biol Psychiatry       Date:  2018-05-09       Impact factor: 13.382

6.  Lexical processing deficits in children with developmental language disorder: An event-related potentials study.

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Journal:  Dev Psychopathol       Date:  2015-05

7.  Non-right handed primary progressive apraxia of speech.

Authors:  Hugo Botha; Joseph R Duffy; Jennifer L Whitwell; Edythe A Strand; Mary M Machulda; Anthony J Spychalla; Nirubol Tosakulwong; Matthew L Senjem; David S Knopman; Ronald C Petersen; Clifford R Jack; Val J Lowe; Keith A Josephs
Journal:  J Neurol Sci       Date:  2018-05-07       Impact factor: 3.181

8.  Mapping the stability of human brain asymmetry across five sex-chromosome aneuploidies.

Authors:  Amy Lin; Liv Clasen; Nancy Raitano Lee; Gregory L Wallace; Francois Lalonde; Jonathan Blumenthal; Jay N Giedd; Armin Raznahan
Journal:  J Neurosci       Date:  2015-01-07       Impact factor: 6.167

9.  Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans.

Authors:  Diego Iacono; Maria Geraci-Erck; Hui Peng; John Paul Bouffard
Journal:  J Vis Exp       Date:  2016-12-18       Impact factor: 1.355

10.  Conceptual and data-based investigation of genetic influences and brain asymmetry: a twin study of multiple structural phenotypes.

Authors:  Lisa T Eyler; Eero Vuoksimaa; Matthew S Panizzon; Christine Fennema-Notestine; Michael C Neale; Chi-Hua Chen; Amy Jak; Carol E Franz; Michael J Lyons; Wesley K Thompson; Kelly M Spoon; Bruce Fischl; Anders M Dale; William S Kremen
Journal:  J Cogn Neurosci       Date:  2013-11-27       Impact factor: 3.225

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