Literature DB >> 23765051

A cancer genetics toolkit improves access to genetic services through documentation and use of the family history by primary-care clinicians.

Maren T Scheuner1, Alison B Hamilton2, Jane Peredo3, Taylor J Sale3, Colletta Austin3, Stuart C Gilman4, M Scott Bowen5, Caroline Lubick Goldzweig1, Martin Lee6, Brian S Mittman3, Elizabeth M Yano6.   

Abstract

PURPOSE: We developed, implemented, and evaluated a multicomponent cancer genetics toolkit designed to improve recognition and appropriate referral of individuals at risk for hereditary cancer syndromes.
METHODS: We evaluated toolkit implementation in the women's clinics at a large Veterans Administration medical center using mixed methods, including pre-post semistructured interviews, clinician surveys, and chart reviews, and during implementation, monthly tracking of genetic consultation requests and use of a reminder in the electronic health record. We randomly sampled 10% of progress notes 6 months before (n = 139) and 18 months during implementation (n = 677).
RESULTS: The toolkit increased cancer family history documentation by almost 10% (26.6% pre- and 36.3% postimplementation). The reminder was a key component of the toolkit; when used, it was associated with a twofold increase in cancer family history documentation (odds ratio = 2.09; 95% confidence interval: 1.39-3.15), and the history was more complete. Patients whose clinicians completed the reminder were twice as likely to be referred for genetic consultation (4.1-9.6%, P < 0.0001).
CONCLUSION: A multicomponent approach to the systematic collection and use of family history by primary-care clinicians increased access to genetic services.

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Mesh:

Year:  2013        PMID: 23765051     DOI: 10.1038/gim.2013.75

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  23 in total

1.  Genetic cancer risk assessment in general practice: systematic review of tools available, clinician attitudes, and patient outcomes.

Authors:  Flore Laforest; Pia Kirkegaard; Baljinder Mann; Adrian Edwards
Journal:  Br J Gen Pract       Date:  2018-12-03       Impact factor: 5.386

Review 2.  What characterizes cancer family history collection tools? A critical literature review.

Authors:  J E Cleophat; H Nabi; S Pelletier; K Bouchard; M Dorval
Journal:  Curr Oncol       Date:  2018-08-14       Impact factor: 3.677

3.  Impact of family history assessment on communication with family members and health care providers: A report from the Family Healthware™ Impact Trial (FHITr).

Authors:  Catharine Wang; Ananda Sen; Melissa Plegue; Mack T Ruffin; Suzanne M O'Neill; Wendy S Rubinstein; Louise S Acheson
Journal:  Prev Med       Date:  2015-04-19       Impact factor: 4.018

4.  Why Is Cancer Genetic Counseling Underutilized by Women Identified as at Risk for Hereditary Breast Cancer? Patient Perceptions of Barriers Following a Referral Letter.

Authors:  Alyssa Kne; Heather Zierhut; Shari Baldinger; Karen K Swenson; Pamela Mink; Patricia McCarthy Veach; Michaela L Tsai
Journal:  J Genet Couns       Date:  2016-11-08       Impact factor: 2.537

5.  Patient and provider perspectives on the development of personalized medicine: a mixed-methods approach.

Authors:  Lauren Puryear; Natalie Downs; Andrea Nevedal; Eleanor T Lewis; Kelly E Ormond; Maria Bregendahl; Carlos J Suarez; Sean P David; Steven Charlap; Isabella Chu; Steven M Asch; Neda Pakdaman; Sang-Ick Chang; Mark R Cullen; Latha Palaniappan
Journal:  J Community Genet       Date:  2017-12-27

6.  The value of a genetic counselor: improving identification of cancer genetic counseling patients with chart review.

Authors:  Jennifer N Eichmeyer; Christa Burnham; Patty Sproat; Rick Tivis; Thomas M Beck
Journal:  J Genet Couns       Date:  2013-10-25       Impact factor: 2.537

Review 7.  Primary care providers' cancer genetic testing-related knowledge, attitudes, and communication behaviors: A systematic review and research agenda.

Authors:  Jada G Hamilton; Ekland Abdiwahab; Heather M Edwards; Min-Lin Fang; Andrew Jdayani; Erica S Breslau
Journal:  J Gen Intern Med       Date:  2016-12-19       Impact factor: 5.128

8.  Integrating Germline Genetics Into Precision Oncology Practice in the Veterans Health Administration: Challenges and Opportunities.

Authors:  Maren T Scheuner; Kenute Myrie; Jane Peredo; Lori Hoffman-Hogg; Margaret Lundquist; Stephanie L Guerra; Douglas Ball
Journal:  Fed Pract       Date:  2020-08

9.  The Integrating Pharmacogenetics in Clinical Care (I-PICC) Study: Protocol for a point-of-care randomized controlled trial of statin pharmacogenetics in primary care.

Authors:  Jason L Vassy; Charles A Brunette; Nilla Majahalme; Sanjay Advani; Lauren MacMullen; Cynthia Hau; Andrew J Zimolzak; Stephen J Miller
Journal:  Contemp Clin Trials       Date:  2018-10-24       Impact factor: 2.226

Review 10.  Initiatives to Scale Up and Expand Reach of Cancer Genomic Services Outside of Specialty Clinical Settings: A Systematic Review.

Authors:  Yue Guan; Colleen M McBride; Hannah Rogers; Jingsong Zhao; Caitlin G Allen; Cam Escoffery
Journal:  Am J Prev Med       Date:  2020-11-07       Impact factor: 5.043

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