Literature DB >> 23751260

Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda.

Jessica E Haberer1, Julius Kiwanuka, Denis Nansera, Conrad Muzoora, Peter W Hunt, Jacquelyn So, Michael O'Donnell, Mark Siedner, Jeffrey N Martin, David R Bangsberg.   

Abstract

A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

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Year:  2013        PMID: 23751260      PMCID: PMC3868644          DOI: 10.1097/QAD.0b013e328363b53f

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  10 in total

1.  Challenges in using mobile phones for collection of antiretroviral therapy adherence data in a resource-limited setting.

Authors:  Jessica E Haberer; Julius Kiwanuka; Denis Nansera; Ira B Wilson; David R Bangsberg
Journal:  AIDS Behav       Date:  2010-12

Review 2.  Measuring adherence to highly active antiretroviral therapy: implications for research and practice.

Authors:  Thomas Kerr; John Walsh; Elisa Lloyd-Smith; Evan Wood
Journal:  Curr HIV/AIDS Rep       Date:  2005-11       Impact factor: 5.071

Review 3.  Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management.

Authors:  Jane M Simoni; Ann E Kurth; Cynthia R Pearson; David W Pantalone; Joseph O Merrill; Pamela A Frick
Journal:  AIDS Behav       Date:  2006-05

4.  Use of electronic monitoring induces a 40-day intervention effect in HIV patients.

Authors:  Ann E Deschamps; Eric Van Wijngaerden; Kris Denhaerynck; Sabina De Geest; Anne-Mieke Vandamme
Journal:  J Acquir Immune Defic Syndr       Date:  2006-10-01       Impact factor: 3.731

5.  Treating our way out of the HIV pandemic: could we, would we, should we?

Authors:  Geoffrey P Garnett; Rebecca F Baggaley
Journal:  Lancet       Date:  2008-11-27       Impact factor: 79.321

6.  Adherence to protease inhibitor therapy and outcomes in patients with HIV infection.

Authors:  D L Paterson; S Swindells; J Mohr; M Brester; E N Vergis; C Squier; M M Wagener; N Singh
Journal:  Ann Intern Med       Date:  2000-07-04       Impact factor: 25.391

7.  Assessing the reporting of adherence and sexual activity in a simulated microbicide trial in South Africa: an interview mode experiment using a placebo gel.

Authors:  Barbara S Mensch; Paul C Hewett; Sharon Abbott; Johanna Rankin; Sarah Littlefield; Khatija Ahmed; Nazira Cassim; Smruti Patel; Gita Ramjee; Thesla Palanee; Stan Mierzwa; Stephanie Skoler-Karpoff
Journal:  AIDS Behav       Date:  2011-02

8.  Real-time adherence monitoring for HIV antiretroviral therapy.

Authors:  Jessica E Haberer; Josh Kahane; Isaac Kigozi; Nneka Emenyonu; Peter Hunt; Jeffrey Martin; David R Bangsberg
Journal:  AIDS Behav       Date:  2010-12

Review 9.  Preventing HIV antiretroviral resistance through better monitoring of treatment adherence.

Authors:  David R Bangsberg
Journal:  J Infect Dis       Date:  2008-05-15       Impact factor: 5.226

10.  Optimizing network connectivity for mobile health technologies in sub-Saharan Africa.

Authors:  Mark J Siedner; Alexander Lankowski; Derrick Musinga; Jonathon Jackson; Conrad Muzoora; Peter W Hunt; Jeffrey N Martin; David R Bangsberg; Jessica E Haberer
Journal:  PLoS One       Date:  2012-09-28       Impact factor: 3.240

  10 in total
  42 in total

Review 1.  Cell Phone-Based and Adherence Device Technologies for HIV Care and Treatment in Resource-Limited Settings: Recent Advances.

Authors:  Jeffrey I Campbell; Jessica E Haberer
Journal:  Curr HIV/AIDS Rep       Date:  2015-12       Impact factor: 5.071

Review 2.  Nonadherence to immunosuppressive therapy in kidney transplant recipients: can technology help?

Authors:  Erika Nerini; Fulvio Bruno; Franco Citterio; Francesco P Schena
Journal:  J Nephrol       Date:  2016-02-17       Impact factor: 3.902

Review 3.  Ethical Questions in Medical Electronic Adherence Monitoring.

Authors:  Jeffrey I Campbell; Nir Eyal; Angella Musiimenta; Jessica E Haberer
Journal:  J Gen Intern Med       Date:  2015-09-10       Impact factor: 5.128

4.  If You Build It, Will They Use It? Preferences for Antiretroviral Therapy (ART) Adherence Monitoring Among People Who Inject Drugs (PWID) in Kazakhstan.

Authors:  Alissa Davis; Lyailya Sarsembayeva; Valeriy Gulyaev; Sholpan Primbetova; Assel Terlikbayeva; Gaukhar Mergenova; Robert H Remien
Journal:  AIDS Behav       Date:  2019-12

Review 5.  Impact of geographic and transportation-related barriers on HIV outcomes in sub-Saharan Africa: a systematic review.

Authors:  Alexander J Lankowski; Mark J Siedner; David R Bangsberg; Alexander C Tsai
Journal:  AIDS Behav       Date:  2014-07

Review 6.  Actionable Adherence Monitoring: Technological Methods to Monitor and Support Adherence to Antiretroviral Therapy.

Authors:  Kate M Bell; Jessica E Haberer
Journal:  Curr HIV/AIDS Rep       Date:  2018-10       Impact factor: 5.071

Review 7.  Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions.

Authors:  Matthew A Spinelli; Jessica E Haberer; Peter R Chai; Jose Castillo-Mancilla; Peter L Anderson; Monica Gandhi
Journal:  Curr HIV/AIDS Rep       Date:  2020-08       Impact factor: 5.071

8.  Novel Approaches for Visualizing and Analyzing Dose-Timing Data from Electronic Drug Monitors, or "How the 'Broken Window' Theory Pertains to ART Adherence".

Authors:  Christopher J Gill; Mary Bachman DeSilva; Davidson H Hamer; Xu Keyi; Ira B Wilson; Lora Sabin
Journal:  AIDS Behav       Date:  2015-11

9.  Super Learner Analysis of Electronic Adherence Data Improves Viral Prediction and May Provide Strategies for Selective HIV RNA Monitoring.

Authors:  Maya L Petersen; Erin LeDell; Joshua Schwab; Varada Sarovar; Robert Gross; Nancy Reynolds; Jessica E Haberer; Kathy Goggin; Carol Golin; Julia Arnsten; Marc I Rosen; Robert H Remien; David Etoori; Ira B Wilson; Jane M Simoni; Judith A Erlen; Mark J van der Laan; Honghu Liu; David R Bangsberg
Journal:  J Acquir Immune Defic Syndr       Date:  2015-05-01       Impact factor: 3.731

10.  Ugandan Study Participants Experience Electronic Monitoring of Antiretroviral Therapy Adherence as Welcomed Pressure to Adhere.

Authors:  Jeffrey I Campbell; Nir Eyal; Angella Musiimenta; Bridget Burns; Sylvia Natukunda; Nicholas Musinguzi; Jessica E Haberer
Journal:  AIDS Behav       Date:  2018-10
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