Literature DB >> 23749527

Extending the convergence of canonical WNT signaling and classic cancer pathways for treatment of malignant peripheral nerve sheath tumors.

Karlyne M Reilly1.   

Abstract

Malignant peripheral nerve sheath tumors (MPNST) are incurable tumors of the Schwann cell lineage that progress unpredictably from benign plexiform neurofibromas. In this issue of Cancer Discovery, Watson and colleagues use an insertional mutagenesis screen combined with network analysis to identify the canonical WNT signaling pathway as an important potential biomarker of tumor progression and target for combination therapy in MPNSTs.

Entities:  

Mesh：

Year:  2013        PMID： 23749527      PMCID： PMC5006627          DOI： 10.1158/2159-8290.CD-13-0192

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  11 in total

Review 1.  Wnt/β-catenin signaling and disease.

Authors:  Hans Clevers; Roel Nusse
Journal:  Cell       Date:  2012-06-08       Impact factor: 41.582

Review 2.  Current status of sporadic and neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.

Authors:  Brigitte C Widemann
Journal:  Curr Oncol Rep       Date:  2009-07       Impact factor: 5.075

3.  CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.

Authors:  Wei Mo; Jian Chen; Amish Patel; Liang Zhang; Vincent Chau; Yanjiao Li; Woosung Cho; Kyun Lim; Jing Xu; Alexander J Lazar; Chad J Creighton; Svetlana Bolshakov; Renée M McKay; Dina Lev; Lu Q Le; Luis F Parada
Journal:  Cell       Date:  2013-02-21       Impact factor: 41.582

4.  Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas.

Authors:  Brigitte C Widemann; Wanda L Salzer; Robert J Arceci; Susan M Blaney; Elizabeth Fox; David End; Andrea Gillespie; Patricia Whitcomb; Joseph S Palumbo; Aaron Pitney; Nalini Jayaprakash; Peter Zannikos; Frank M Balis
Journal:  J Clin Oncol       Date:  2006-01-20       Impact factor: 44.544

5.  Nuclear translocation of β-catenin and decreased expression of epithelial cadherin in human papillomavirus-positive tonsillar cancer: an early event in human papillomavirus-related tumour progression?

Authors:  Markus Stenner; Basima Yosef; Christian U Huebbers; Simon F Preuss; Hans-Peter Dienes; Ernst-Jan M Speel; Margarete Odenthal; Jens P Klussmann
Journal:  Histopathology       Date:  2011-03-25       Impact factor: 5.087

6.  Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations.

Authors:  Ce Liu; Yanyang Tu; Xiaoyang Sun; Jian Jiang; Xiaodong Jin; Xiangfei Bo; Zhengming Li; Aimiao Bian; Xiaodong Wang; Dai Liu; Zhengmei Wang; Lianshu Ding
Journal:  Clin Exp Med       Date:  2010-08-31       Impact factor: 3.984

7.  Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance.

Authors:  Adrienne L Watson; Eric P Rahrmann; Branden S Moriarity; Kwangmin Choi; Caitlin B Conboy; Andrew D Greeley; Amanda L Halfond; Leah K Anderson; Brian R Wahl; Vincent W Keng; Anthony E Rizzardi; Colleen L Forster; Margaret H Collins; Aaron L Sarver; Margaret R Wallace; Stephen C Schmechel; Nancy Ratner; David A Largaespada
Journal:  Cancer Discov       Date:  2013-03-27       Impact factor: 39.397

8.  Treatment of glioblastoma multiforme using a combination of small interfering RNA targeting epidermal growth factor receptor and β-catenin.

Authors:  Kui Wang; James O Park; Miqin Zhang
Journal:  J Gene Med       Date:  2013-01       Impact factor: 4.565

9.  mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.

Authors:  Kathryn E O'Reilly; Fredi Rojo; Qing-Bai She; David Solit; Gordon B Mills; Debra Smith; Heidi Lane; Francesco Hofmann; Daniel J Hicklin; Dale L Ludwig; Jose Baselga; Neal Rosen
Journal:  Cancer Res       Date:  2006-02-01       Impact factor: 12.701

Review 10.  Convergence between Wnt-β-catenin and EGFR signaling in cancer.

Authors:  Tianhui Hu; Cunxi Li
Journal:  Mol Cancer       Date:  2010-09-09       Impact factor: 27.401
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  2 in total

1.  Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours.

Authors:  Laura E Thomas; Jincy Winston; Ellie Rad; Matthew Mort; Kayleigh M Dodd; Andrew R Tee; Fionnuala McDyer; Stephen Moore; David N Cooper; Meena Upadhyaya
Journal:  Hum Genomics       Date:  2015-02-15       Impact factor: 4.639

2.  WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth.

Authors:  Craig S Thomson; Jay Pundavela; Melissa R Perrino; Robert A Coover; Kwangmin Choi; Katherine E Chaney; Tilat A Rizvi; David A Largaespada; Nancy Ratner
Journal:  Oncogene       Date:  2021-06-02       Impact factor: 9.867
  2 in total

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