Literature DB >> 23743355

Tight junction proteins: from barrier to tumorigenesis.

E Aaron Runkle1, David Mu.   

Abstract

The tight junction is a multi-protein complex and is the apical most junctional complex in certain epithelial and endothelial cells. A great deal of attention has been devoted to the understanding of these proteins in contributing to the barrier function - that is, regulating the paracellular flux or permeability between adjacent cells. However, tight junction proteins are now recognized as having functions beyond the barrier. The focus of this review is to discuss the barrier function of the tight junction and to summarize the literature with a focus on the role of tight junction proteins in proliferation, transformation, and metastasis.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Cancer; Claudin; Metastasis; Occludin; Tight junction

Mesh：

Substances：

Year:  2013        PMID： 23743355      PMCID： PMC3752309          DOI： 10.1016/j.canlet.2013.05.038

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  133 in total

1.  Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast.

Authors:  Scott L Kominsky; Pedram Argani; Dorian Korz; Ella Evron; Venu Raman; Elizabeth Garrett; Alan Rein; Guido Sauter; Olli-P Kallioniemi; Saraswati Sukumar
Journal:  Oncogene       Date:  2003-04-03       Impact factor: 9.867

2.  The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells. Evidence for a role of beta-catenin/Tcf/Lef signaling.

Authors:  M Reichert; T Müller; W Hunziker
Journal:  J Biol Chem       Date:  2000-03-31       Impact factor: 5.157

3.  Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor slug.

Authors:  Z Wang; P Wade; K J Mandell; A Akyildiz; C A Parkos; R J Mrsny; A Nusrat
Journal:  Oncogene       Date:  2006-08-21       Impact factor: 9.867

Review 4.  Transcriptional control of lung morphogenesis.

Authors:  Yutaka Maeda; Vrushank Davé; Jeffrey A Whitsett
Journal:  Physiol Rev       Date:  2007-01       Impact factor: 37.312

5.  CLDN16 genotype predicts renal decline in familial hypomagnesemia with hypercalciuria and nephrocalcinosis.

Authors:  Martin Konrad; Jianghui Hou; Stefanie Weber; Jörg Dötsch; Jameela A Kari; Tomas Seeman; Eberhard Kuwertz-Bröking; Amira Peco-Antic; Velibor Tasic; Katalin Dittrich; Hammad O Alshaya; Rodo O von Vigier; Sabina Gallati; Daniel A Goodenough; André Schaller
Journal:  J Am Soc Nephrol       Date:  2007-11-14       Impact factor: 10.121

6.  The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.

Authors:  Francisco Valdés; Alberto M Alvarez; Annamaria Locascio; Sonia Vega; Blanca Herrera; Margarita Fernández; Manuel Benito; M Angela Nieto; Isabel Fabregat
Journal:  Mol Cancer Res       Date:  2002-11       Impact factor: 5.852

7.  Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration.

Authors:  Natalia Elfimova; Elisabeth Sievers; Hannah Eischeid; Monika Kwiecinski; Andrea Noetel; Heike Hunt; Diana Becker; Peter Frommolt; Maria Quasdorff; Hans Michael Steffen; Peter Nürnberg; Reinhard Büttner; Andreas Teufel; Hans-Peter Dienes; Uta Drebber; Margarete Odenthal
Journal:  Biochim Biophys Acta       Date:  2013-02-05

8.  Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

Authors:  P Dhawan; R Ahmad; R Chaturvedi; J J Smith; R Midha; M K Mittal; M Krishnan; X Chen; S Eschrich; T J Yeatman; R C Harris; M K Washington; K T Wilson; R D Beauchamp; A B Singh
Journal:  Oncogene       Date:  2011-03-07       Impact factor: 9.867

9.  Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions.

Authors:  M Itoh; H Sasaki; M Furuse; H Ozaki; T Kita; S Tsukita
Journal:  J Cell Biol       Date:  2001-08-06       Impact factor: 10.539

10.  Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice.

Authors:  Mikio Furuse; Masaki Hata; Kyoko Furuse; Yoko Yoshida; Akinori Haratake; Yoshinobu Sugitani; Tetsuo Noda; Akiharu Kubo; Shoichiro Tsukita
Journal:  J Cell Biol       Date:  2002-03-11       Impact factor: 10.539
View more
  77 in total

Review 1.  The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease.

Authors:  Tamina Seeger-Nukpezah; Daniel M Geynisman; Anna S Nikonova; Thomas Benzing; Erica A Golemis
Journal:  Nat Rev Nephrol       Date:  2015-04-14       Impact factor: 28.314

2.  Effects of histone deacetylase inhibitors Tricostatin A and Quisinostat on tight junction proteins of human lung adenocarcinoma A549 cells and normal lung epithelial cells.

Authors:  Yuma Shindo; Wataru Arai; Takumi Konno; Takayuki Kohno; Yuki Kodera; Hirofumi Chiba; Masahiro Miyajima; Yuji Sakuma; Atsushi Watanabe; Takashi Kojima
Journal:  Histochem Cell Biol       Date:  2021-05-11       Impact factor: 4.304

Review 3.  Mechanisms regulating endothelial permeability.

Authors:  Sukriti Sukriti; Mohammad Tauseef; Pascal Yazbeck; Dolly Mehta
Journal:  Pulm Circ       Date:  2014-12       Impact factor: 3.017

4.  Cell-cell junctions: structure and regulation in physiology and pathology.

Authors:  Mir S Adil; S Priya Narayanan; Payaningal R Somanath
Journal:  Tissue Barriers       Date:  2020-12-10

5.  HIV-1 impairs human retinal pigment epithelial barrier function: possible association with the pathogenesis of HIV-associated retinopathy.

Authors:  Suiyi Tan; Heng Duan; Tianrong Xun; Wei Ci; Jiayin Qiu; Fei Yu; Xuyan Zhao; Linxuan Wu; Lin Li; Lu Lu; Shibo Jiang; Shuwen Liu
Journal:  Lab Invest       Date:  2014-05-19       Impact factor: 5.662

Review 6.  The role of epithelial tight junctions involved in pathogen infections.

Authors:  Ru-Yi Lu; Wan-Xi Yang; Yan-Jun Hu
Journal:  Mol Biol Rep       Date:  2014-06-26       Impact factor: 2.316

Review 7.  Gut Microbiota-Kidney Cross-Talk in Acute Kidney Injury.

Authors:  Jing Gong; Sanjeev Noel; Jennifer L Pluznick; Abdel Rahim A Hamad; Hamid Rabb
Journal:  Semin Nephrol       Date:  2019-01       Impact factor: 5.299

8.  Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.

Authors:  Xiupeng Zhang; Guiyang Jiang; Jingjing Wu; Haijing Zhou; Yong Zhang; Yuan Miao; Yangyang Feng; Juanhan Yu
Journal:  Oncol Lett       Date:  2018-01-16       Impact factor: 2.967

Review 9.  Circulating tumor cells and epithelial, mesenchymal and stemness markers: characterization of cell subpopulations.

Authors:  Guislaine Barriere; Pietro Fici; Giulia Gallerani; Francesco Fabbri; Wainer Zoli; Michel Rigaud
Journal:  Ann Transl Med       Date:  2014-11

10.  Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein.

Authors:  Florencia Facciuto; Marina Bugnon Valdano; Federico Marziali; Paola Massimi; Lawrence Banks; Ana Laura Cavatorta; Daniela Gardiol
Journal:  Mol Oncol       Date:  2014-01-14       Impact factor: 6.603
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.