Literature DB >> 23738252

Experimental basis of the hypotheses on the mechanism of skeletal muscle contraction.

Enrico Grazi1.   

Abstract

With time clever hypotheses may be accepted as "facts" without being supported by solid experimental evidence. In our opinion this happened with muscle contraction where pure suggestions still occupy the scene and delay the progress of the research. Among these suggestions are: 1. the believe that viscosity is irrelevant in the economy of muscle contraction, 2. the concept of the drag stroke, 3. some interpretations of the significance of the Huxley-Simmons manoeuvre, 4. the definition of the load as a force/cross-section without taking into consideration the possible, divergent effects of the infinite mass x acceleration couples. Technical questions are also raised since it is apparent that measuring equipments interfere with the measure itself.

Entities:  

Keywords:  Huxley - Simmons manoeuvre; acceleration of the load; drag stroke; muscle contraction; viscosity

Year:  2012        PMID: 23738252      PMCID: PMC3666480     

Source DB:  PubMed          Journal:  Muscles Ligaments Tendons J        ISSN: 2240-4554


  49 in total

1.  Thermodynamic features of myosin filament suspensions: implications for the modeling of muscle contraction.

Authors:  E Grazi; O Cintio
Journal:  Biophys J       Date:  2001-07       Impact factor: 4.033

2.  Muscle contraction: viscous-like frictional forces and the impulsive model.

Authors:  G F Elliott; C R Worthington
Journal:  Int J Biol Macromol       Date:  2001-10-22       Impact factor: 6.953

3.  Enzymatic properties of the heavy meromyosin subfragment of cardiac myosin from normal and thyrotoxic rabbits.

Authors:  S K Banerjee; E G Kabbas; E Morkin
Journal:  J Biol Chem       Date:  1977-10-10       Impact factor: 5.157

4.  Muscle mechanism: The acceleration of the load.

Authors:  Enrico Grazi
Journal:  Arch Biochem Biophys       Date:  2010-09-15       Impact factor: 4.013

5.  Tension responses to sudden length change in stimulated frog muscle fibres near slack length.

Authors:  L E Ford; A F Huxley; R M Simmons
Journal:  J Physiol       Date:  1977-07       Impact factor: 5.182

Review 6.  Theoretical formalism for the sliding filament model of contraction of striated muscle. Part I.

Authors:  T L Hill
Journal:  Prog Biophys Mol Biol       Date:  1974       Impact factor: 3.667

7.  Crossbridge properties investigated by fast ramp stretching of activated frog muscle fibres.

Authors:  M Angela Bagni; Giovanni Cecchi; Barbara Colombini
Journal:  J Physiol       Date:  2005-03-17       Impact factor: 5.182

8.  Equilibrium muscle cross-bridge behavior. Theoretical considerations.

Authors:  M Schoenberg
Journal:  Biophys J       Date:  1985-09       Impact factor: 4.033

9.  The velocity of unloaded shortening and its relation to sarcomere length and isometric force in vertebrate muscle fibres.

Authors:  K A Edman
Journal:  J Physiol       Date:  1979-06       Impact factor: 5.182

10.  Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known.

Authors:  Enrico Grazi; Sara Pozzati
Journal:  Theor Biol Med Model       Date:  2010-06-18       Impact factor: 2.432

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  6 in total

1.  Tissue engineering for skeletal muscle regeneration.

Authors:  Roberto Rizzi; Claudia Bearzi; Arianna Mauretti; Sergio Bernardini; Stefano Cannata; Cesare Gargioli
Journal:  Muscles Ligaments Tendons J       Date:  2012-10-16

2.  Original article Muscle extracellular matrix degradation and contractibility following tendon rupture and disuse.

Authors:  Qia Zhang; Sunil K Joshi; Givenchy Manzano; David H Lovett; Hubert T Kim; Xuhui Liu
Journal:  Muscles Ligaments Tendons J       Date:  2013-05-21

3.  Muscle as a molecular machine for protecting joints and bones by absorbing mechanical impacts.

Authors:  Armen Sarvazyan; Oleg Rudenko; Salavat Aglyamov; Stanislav Emelianov
Journal:  Med Hypotheses       Date:  2014-04-23       Impact factor: 1.538

4.  Matrix metalloproteinase-2 plays a critical role in overload induced skeletal muscle hypertrophy.

Authors:  Qia Zhang; Sunil K Joshi; David H Lovett; Bryon Zhang; Sue Bodine; Hubert T Kim; Xuhui Liu
Journal:  Muscles Ligaments Tendons J       Date:  2015-02-05

5.  Matrix metalloproteinase-2 plays a critical role in overload induced skeletal muscle hypertrophy.

Authors:  Qia Zhang; Sunil K Joshi; David H Lovett; Bryon Zhang; Sue Bodine; Hubert Kim; Xuhui Liu
Journal:  Muscles Ligaments Tendons J       Date:  2014-11-17

6.  The cross-bridge of skeletal muscle is not synchronized either by length or force step.

Authors:  Enrico Grazi
Journal:  Int J Mol Sci       Date:  2015-05-27       Impact factor: 5.923

  6 in total

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