Literature DB >> 23737110

The status of serum vitamin D in patients attending a general rheumatology clinic in the UK.

Malack Alachkar1, Yee Ping Teoh, Margaret M O'Sullivan.   

Abstract

Vitamin D deficiency may be involved in the pathogenesis of several inflammatory conditions. This study aimed to determine the status of vitamin D in the rheumatology patients who were diagnosed with different rheumatic, inflammatory and non-inflammatory diseases. In this cross-sectional observational study, we reviewed the levels of serum vitamin D in patients who attended the general rheumatology clinics for the first time between May 2012 and October 2012. A total of 61 patients were included in this study. Twenty-five patients (41 %) had vitamin D insufficiency and two patients (3.3 %) were vitamin D deficient. Sixteen patients had an inflammatory condition and vitamin D was low in five patients (31 %). Among the 45 patients who had a non-inflammatory rheumatic condition, 20 patients (44 %) had low vitamin D. There was no significant statistical difference (P = 0.3) in the incidence of low vitamin D between the two groups. We found no significant correlation either between CRP and vitamin D (r = -0.02 (95 % confidence interval -0.28 to 0.23), P = 0.8). In this limited study, which was undertaken in the summer months, we concluded that there was no significant difference in vitamin D status between patients with inflammatory and non-inflammatory rheumatic conditions.

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Year:  2013        PMID: 23737110     DOI: 10.1007/s10067-013-2275-6

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  11 in total

1.  Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNFα blockade: results from a prospective cohort study.

Authors:  Paul Welsh; Mike J L Peters; Iain B McInnes; Willem F Lems; Paul T Lips; Gayle McKellar; Susan Knox; A Michael Wallace; Ben A C Dijkmans; Michael T Nurmohamed; Naveed Sattar
Journal:  Ann Rheum Dis       Date:  2010-11-03       Impact factor: 19.103

Review 2.  Vitamin D endocrine system involvement in autoimmune rheumatic diseases.

Authors:  Maurizio Cutolo; Carmen Pizzorni; Alberto Sulli
Journal:  Autoimmun Rev       Date:  2011-08-16       Impact factor: 9.754

Review 3.  Vitamin D and autoimmune rheumatologic disorders.

Authors:  Christina F Pelajo; Jorge M Lopez-Benitez; Laurie C Miller
Journal:  Autoimmun Rev       Date:  2010-02-08       Impact factor: 9.754

4.  The relationship between vitamin D and disease activity and functional health status in rheumatoid arthritis.

Authors:  Ayşe Dicle Turhanoğlu; Hayal Güler; Zafer Yönden; Fatma Aslan; Ayhan Mansuroglu; Cahit Ozer
Journal:  Rheumatol Int       Date:  2010-03-19       Impact factor: 2.631

5.  Prevalence of vitamin D insufficiency/deficiency in rheumatoid arthritis and associations with disease severity and activity.

Authors:  Gail S Kerr; Iraj Sabahi; John S Richards; Liron Caplan; Grant W Cannon; Andreas Reimold; Geoffrey M Thiele; Dannette Johnson; Ted R Mikuls
Journal:  J Rheumatol       Date:  2010-10-15       Impact factor: 4.666

Review 6.  Vitamin D deficiency: subclinical and clinical consequences on musculoskeletal health.

Authors:  Muhammad Haroon; Oliver FitzGerald
Journal:  Curr Rheumatol Rep       Date:  2012-06       Impact factor: 4.592

7.  Decreased plasma vitamin D levels in patients with undifferentiated spondyloarthritis and ankylosing spondylitis.

Authors:  Sukran Erten; Orhan Kucuksahin; Ali Sahin; Alpaslan Altunoglu; Mesut Akyol; Cemile Koca
Journal:  Intern Med       Date:  2013-02-01       Impact factor: 1.271

Review 8.  The implication of vitamin D and autoimmunity: a comprehensive review.

Authors:  Chen-Yen Yang; Patrick S C Leung; Iannis E Adamopoulos; M Eric Gershwin
Journal:  Clin Rev Allergy Immunol       Date:  2013-10       Impact factor: 8.667

9.  Potential benefits of vitamin D for patients with systemic lupus erythematosus.

Authors:  Abha Singh; Diane L Kamen
Journal:  Dermatoendocrinol       Date:  2012-04-01

10.  The effect of vitamin D levels on the assessment of disease activity in rheumatoid arthritis.

Authors:  M J Higgins; S L Mackie; N Thalayasingam; S J Bingham; J Hamilton; C A Kelly
Journal:  Clin Rheumatol       Date:  2013-01-23       Impact factor: 2.980

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