Literature DB >> 23733496

Structures of KOD and 9°N DNA polymerases complexed with primer template duplex.

Konrad Bergen1, Karin Betz, Wolfram Welte, Kay Diederichs, Andreas Marx.   

Abstract

Replicate it: Structures of KOD and 9°N DNA polymerases, two enzymes that are widely used to replicate DNA with highly modified nucleotides, were solved at high resolution in complex with primer/template duplex. The data elucidate substrate interaction of the two enzymes and pave the way for further optimisation of the enzymes and substrates.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23733496     DOI： 10.1002/cbic.201300175

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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