Literature DB >> 23730228

DILI: New Insights into Diagnosis and Management.

Thanh Tran1, William M Lee.   

Abstract

Drug-induced liver injury continues to have a significant impact. With over 1000 drugs now registered as causing DILI, this form of liver injury is the most cited reason for withdrawal of a drug from the marketplace. Despite this, the diagnosis of DILI continues to rely on subjective measures and expert opinion with results that are both difficult to verify and reproduce. However, recent developments in DILI research may provide new insights to improve diagnosis and treatment in the future.

Entities:  

Keywords:  acetaminophen; biotransformation; genetic polymorphism; genome wide association study; herbal and dietary supplements

Year:  2013        PMID： 23730228      PMCID： PMC3666953          DOI： 10.1007/s11901-012-0159-x

Source DB:  PubMed          Journal:  Curr Hepat Rep        ISSN： 1540-3416


  42 in total

1.  Drug-induced liver injury: mechanisms and test systems.

Authors:  D M Bissell; G J Gores; D L Laskin; J H Hoofnagle
Journal:  Hepatology       Date:  2001-04       Impact factor: 17.425

2.  Critical role of CD44 in hepatotoxin-mediated liver injury.

Authors:  Kiminori Kimura; Masahito Nagaki; Kazuhiro Kakimi; Masanao Saio; Tomomi Saeki; Yumiko Okuda; Kazuo Kuwata; Hisataka Moriwaki
Journal:  J Hepatol       Date:  2008-03-11       Impact factor: 25.083

Review 3.  Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis.

Authors:  M A Robin; M Le Roy; V Descatoire; D Pessayre
Journal:  J Hepatol       Date:  1997       Impact factor: 25.083

4.  HLA association of amoxicillin-clavulanate--induced hepatitis.

Authors:  M L Hautekeete; Y Horsmans; C Van Waeyenberge; C Demanet; J Henrion; L Verbist; R Brenard; C Sempoux; P P Michielsen; P S Yap; J Rahier; A P Geubel
Journal:  Gastroenterology       Date:  1999-11       Impact factor: 22.682

5.  Causality assessment of adverse reactions to drugs--II. An original model for validation of drug causality assessment methods: case reports with positive rechallenge.

Authors:  C Benichou; G Danan; A Flahault
Journal:  J Clin Epidemiol       Date:  1993-11       Impact factor: 6.437

6.  Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study.

Authors:  Anne M Larson; Julie Polson; Robert J Fontana; Timothy J Davern; Ezmina Lalani; Linda S Hynan; Joan S Reisch; Frank V Schiødt; George Ostapowicz; A Obaid Shakil; William M Lee
Journal:  Hepatology       Date:  2005-12       Impact factor: 17.425

7.  Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method.

Authors:  Don C Rockey; Leonard B Seeff; James Rochon; James Freston; Naga Chalasani; Maurizio Bonacini; Robert J Fontana; Paul H Hayashi
Journal:  Hepatology       Date:  2010-06       Impact factor: 17.425

8.  Co-amoxiclav jaundice: clinical and histological features and HLA class II association.

Authors:  J O'Donohue; K A Oien; P Donaldson; J Underhill; M Clare; R N MacSween; P R Mills
Journal:  Gut       Date:  2000-11       Impact factor: 23.059

9.  Leflunomide-induced acute hepatitis.

Authors:  C Sevilla-Mantilla; L Ortega; J A G Agúndez; B Fernández-Gutiérrez; J M Ladero; M Díaz-Rubio
Journal:  Dig Liver Dis       Date:  2004-01       Impact factor: 4.088

Review 10.  Acetaminophen hepatotoxicity and acute liver failure.

Authors:  Linda J Chun; Myron J Tong; Ronald W Busuttil; Jonathan R Hiatt
Journal:  J Clin Gastroenterol       Date:  2009-04       Impact factor: 3.062
View more
  3 in total

Review 1.  MicroRNAs in Drug-induced Liver Injury.

Authors:  Li-Min Li; Dong Wang; Ke Zen
Journal:  J Clin Transl Hepatol       Date:  2014-09-15

2.  The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.

Authors:  Lucía Barbier-Torres; Paula Iruzubieta; David Fernández-Ramos; Teresa C Delgado; Daniel Taibo; Virginia Guitiérrez-de-Juan; Marta Varela-Rey; Mikel Azkargorta; Nicolas Navasa; Pablo Fernández-Tussy; Imanol Zubiete-Franco; Jorge Simon; Fernando Lopitz-Otsoa; Sofia Lachiondo-Ortega; Javier Crespo; Steven Masson; Misti Vanette McCain; Erica Villa; Helen Reeves; Felix Elortza; Maria Isabel Lucena; Maria Isabel Hernández-Alvarez; Antonio Zorzano; Raúl J Andrade; Shelly C Lu; José M Mato; Juan Anguita; Mercedes Rincón; María Luz Martínez-Chantar
Journal:  Nat Commun       Date:  2017-12-12       Impact factor: 14.919

Review 3.  Systematic Review on Chinese Herbal Medicine Induced Liver Injury.

Authors:  Peng Zhang; Yongan Ye; Xianzhao Yang; Yuntao Jiao
Journal:  Evid Based Complement Alternat Med       Date:  2016-08-29       Impact factor: 2.629
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.