Literature DB >> 23729204

Impact of race/ethnicity on laryngeal cancer in patients treated at a Veterans Affairs Medical Center.

Vlad C Sandulache1, Mark W Kubik, Heath D Skinner, Joseph A Malsky, Alexander H Gelbard, Jose P Zevallos.   

Abstract

OBJECTIVES/HYPOTHESIS: Black patients generally present with advanced head and neck cancer resulting in decreased survival. The objective of this study was to determine whether equal access to laryngeal cancer care in a tertiary care Veterans Affairs (VA) Medical Center would result in similar survival for white and black patients. STUDY
DESIGN: Retrospective chart review.
METHODS: Patient and tumor characteristics, compliance with National Comprehensive Cancer Network (NCCN) guidelines, and survival outcomes were collected for 205 male patients with squamous cell carcinoma of the larynx treated between 2000 and 2012 at the Michael E. DeBakey Veterans Affairs Medical Center.
RESULTS: Black patients constituted 33% of the entire cohort, were older (mean age, 65.1 vs. 62.1 years), and consumed less tobacco (46.6 vs. 65.8 mean pack-years) than white patients. Disease stage and compliance with NCCN guidelines were not affected by race. Mean follow up time was 3.6 years. A higher recurrence rate was noted among white patients (24% vs. 15%, P < .05). Neither disease-free survival (DFS) nor overall survival (OS) was significantly different between black and white patients (DFS 69% vs. 68%, P = .7; OS 68% vs. 77%, P = .1).
CONCLUSIONS: Utilization of a multidisciplinary approach to laryngeal cancer care at the VA medical center allows for high compliance with NCCN guidelines and excellent oncologic outcomes. Ethnicity did not impact stage at presentation, treatment selection, or treatment intensity in this patient cohort. Our data suggest that cancer care at a VA medical center results in clinical outcomes that do not significantly vary based on patient race.
Copyright © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Race; larynx; outcomes; survival; veteran

Mesh:

Year:  2013        PMID: 23729204     DOI: 10.1002/lary.24058

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  7 in total

1.  How do integrated health care systems address racial and ethnic disparities in colon cancer?

Authors:  Kim F Rhoads; Manali I Patel; Yifei Ma; Laura A Schmidt
Journal:  J Clin Oncol       Date:  2015-01-26       Impact factor: 44.544

2.  The complex relation between race, sex, and human papillomavirus status in head and neck cancer.

Authors:  Jose P Zevallos; Angela L Mazul
Journal:  Cancer       Date:  2017-02-27       Impact factor: 6.860

3.  Persistent ethnicity-associated disparity in anti-tumor effectiveness of immune checkpoint inhibitors despite equal access.

Authors:  Marcus A Florez; Jan O Kemnade; Nan Chen; Wendy Du; Anita L Sabichi; Daniel Y Wang; Quillan Huang; Courtney N Miller-Chism; Aparna Jotwani; Albert C Chen; David Hernandez; Vlad C Sandulache
Journal:  Cancer Res Commun       Date:  2022-07-26

4.  Oropharyngeal cancer as a driver of racial outcome disparities in squamous cell carcinoma of the head and neck: 10-year experience at the University of Maryland Greenebaum Cancer Center.

Authors:  Dan P Zandberg; Sandy Liu; Olga Goloubeva; Robert Ord; Scott E Strome; Mohan Suntharalingam; Rodney Taylor; Robert E Morales; Jeffrey S Wolf; Ann Zimrin; Joshua E Lubek; Lisa M Schumaker; Kevin J Cullen
Journal:  Head Neck       Date:  2015-06-30       Impact factor: 3.147

5.  An assessment of racial differences in epidemiological, clinical and psychosocial factors among head and neck cancer patients at the time of surgery.

Authors:  Anvesh Kompelli; Kathleen B Cartmell; Katherine R Sterba; Anthony J Alberg; Christopher C Xiao; Amit J Sood; Elizabeth Garrett-Mayer; Shai J White-Gilbertson; Steven A Rosenzweig; Terry A Day
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2020-03-05

6.  Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival.

Authors:  Peter A Richardson; Sagar Kansara; George G Chen; Anita Sabichi; Andrew G Sikora; Robert B Parke; Donald T Donovan; Elizabeth Chiao; Vlad C Sandulache
Journal:  Laryngoscope Investig Otolaryngol       Date:  2018-08-09

Review 7.  Disparities in health in the United States: An overview of the social determinants of health for otolaryngologists.

Authors:  Regan W Bergmark; Ahmad R Sedaghat
Journal:  Laryngoscope Investig Otolaryngol       Date:  2017-05-28
  7 in total

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