Literature DB >> 23729167

Role of T cells in the modulation of PTH action: physiological and clinical significance.

Roberto Pacifici1.   

Abstract

Osteoimmunology is new field of research dedicated to the study of the interactions between the immune system and bone. Among the cells of the immune system that regulate bone and hemopoietic cells are T lymphocytes. These cells secrete osteoclastogenic cytokines such as RANKL and TNF, as well as factors that stimulate bone formation and hemopoietic cells, one of which is Wnt10b. This article will review the evidence that T cells are implicated in the mechanism of action of parathyroid hormone (PTH) in bone and on the hemopoietic system.

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Year:  2013        PMID： 23729167      PMCID： PMC3815684          DOI： 10.1007/s12020-013-9960-8

Source DB:  PubMed          Journal:  Endocrine        ISSN： 1355-008X            Impact factor:   3.633


  45 in total

1.  The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery.

Authors:  B Ernst; D S Lee; J M Chang; J Sprent; C D Surh
Journal:  Immunity       Date:  1999-08       Impact factor: 31.745

2.  Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone.

Authors:  L M Calvi; N A Sims; J L Hunzelman; M C Knight; A Giovannetti; J M Saxton; H M Kronenberg; R Baron; E Schipani
Journal:  J Clin Invest       Date:  2001-02       Impact factor: 14.808

Review 3.  New understanding and treatments for osteoporosis.

Authors:  G Mazziotti; J Bilezikian; E Canalis; D Cocchi; A Giustina
Journal:  Endocrine       Date:  2012-02       Impact factor: 3.633

4.  Inhibition of antigen presentation and T cell costimulation blocks PTH-induced bone loss.

Authors:  Brahmchetna Bedi; Jau-Yi Li; Francesco Grassi; Hesham Tawfeek; M Neale Weitzmann; Roberto Pacifici
Journal:  Ann N Y Acad Sci       Date:  2010-03       Impact factor: 5.691

5.  Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.

Authors:  Simón Méndez-Ferrer; Tatyana V Michurina; Francesca Ferraro; Amin R Mazloom; Ben D Macarthur; Sergio A Lira; David T Scadden; Avi Ma'ayan; Grigori N Enikolopov; Paul S Frenette
Journal:  Nature       Date:  2010-08-12       Impact factor: 49.962

6.  Absence of response to human parathyroid hormone in athymic mice grafted with human parathyroid adenoma, hyperplasia or parathyroid cells maintained in culture.

Authors:  B G Hory; M C Roussanne; S Rostand; A Bourdeau; T B Drüeke; J Gogusev
Journal:  J Endocrinol Invest       Date:  2000-05       Impact factor: 4.256

7.  Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics.

Authors:  Ling Qin; Ping Qiu; Luquan Wang; Xin Li; John T Swarthout; Patricia Soteropoulos; Peter Tolias; Nicola C Partridge
Journal:  J Biol Chem       Date:  2003-03-18       Impact factor: 5.157

8.  Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss.

Authors:  Hesham Tawfeek; Brahmchetna Bedi; Jau-Yi Li; Jonathan Adams; Tatsuya Kobayashi; M Neale Weitzmann; Henry M Kronenberg; Roberto Pacifici
Journal:  PLoS One       Date:  2010-08-20       Impact factor: 3.240

Review 9.  CD8(+) T cells: foot soldiers of the immune system.

Authors:  Nu Zhang; Michael J Bevan
Journal:  Immunity       Date:  2011-08-26       Impact factor: 31.745

10.  Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor.

Authors:  Masaki Kato; Millan S Patel; Regis Levasseur; Ivan Lobov; Benny H-J Chang; Donald A Glass; Christine Hartmann; Lan Li; Tae-Ho Hwang; Cory F Brayton; Richard A Lang; Gerard Karsenty; Lawrence Chan
Journal:  J Cell Biol       Date:  2002-04-15       Impact factor: 10.539
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  22 in total

1.  Effects of denosumab on peripheral lymphocyte subpopulations.

Authors:  Maurizio Rossini; Ombretta Viapiana; Silvano Adami; Luca Idolazzi; Francesco Ghellere; Gaia Tripi; Riccardo Ortolani; Roberta Zanotti; Davide Gatti
Journal:  Endocrine       Date:  2015-08-20       Impact factor: 3.633

2.  CD8+ Foxp3+ T Cells Affect Alveolar Bone Homeostasis via Modulating Tregs/Th17 During Induced Periodontitis: an Adoptive Transfer Experiment.

Authors:  Y K Han; Y Jin; Y B Miao; T Shi; X P Lin
Journal:  Inflammation       Date:  2018-10       Impact factor: 4.092

Review 3.  Parathyroid hormone: anabolic and catabolic actions on the skeleton.

Authors:  Barbara C Silva; John P Bilezikian
Journal:  Curr Opin Pharmacol       Date:  2015-04-05       Impact factor: 5.547

Review 4.  Osteoporosis in Human Immunodeficiency Virus Patients - An Emerging Clinical Concern.

Authors:  Filippo Maffezzoni; Teresa Porcelli; Ioannis Karamouzis; Eugenia Quiros-Roldan; Francesco Castelli; Gherardo Mazziotti; Andrea Giustina
Journal:  Eur Endocrinol       Date:  2014-02-28

Review 5.  Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling.

Authors:  Janet L Crane; Xu Cao
Journal:  J Clin Invest       Date:  2014-02-03       Impact factor: 14.808

Review 6.  Bone and the Immune System.

Authors:  M Neale Weitzmann
Journal:  Toxicol Pathol       Date:  2017-10-18       Impact factor: 1.902

Review 7.  Regulation of Bone Remodeling by Parathyroid Hormone.

Authors:  Marc N Wein; Henry M Kronenberg
Journal:  Cold Spring Harb Perspect Med       Date:  2018-08-01       Impact factor: 6.915

8.  Association between calcaneus quantitative ultrasound (QUS) parameters and thyroid status in middle-aged and elderly Chinese men with euthyroidism: a population-based cross-sectional study.

Authors:  Yun Shi; Min Sun; Zhixiao Wang; Qi Fu; Mengdie Cao; Zhenxin Zhu; Chuchen Meng; Jia Mao; Yu Duan; Wei Tang; Xiaoping Huang; Jieli Lu; Yufang Bi; Guang Ning; Wei He; Tao Yang
Journal:  Endocrine       Date:  2014-01-24       Impact factor: 3.633

Review 9.  Advances in treatment of glucocorticoid-induced osteoporosis.

Authors:  Emory Hsu; Mark Nanes
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2017-12       Impact factor: 3.243

10.  Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH-induced bone anabolism in mice.

Authors:  Mingcan Yu; Patrizia D'Amelio; Abdul Malik Tyagi; Chiara Vaccaro; Jau-Yi Li; Emory Hsu; Ilaria Buondonno; Francesca Sassi; Jonathan Adams; M Neale Weitzmann; Richard DiPaolo; Roberto Pacifici
Journal:  EMBO Rep       Date:  2017-11-20       Impact factor: 8.807
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