AIM: The aim of the study was to assess and compare the effect of chlorhexidine varnish and fluoride varnish application on Streptococcus mutans counts in plaque of occlusal pits and fissures of permanent mandibular first molars. MATERIALS AND METHODS: The study was an in vivo comparative study, conducted among 50 schoolchildren aged 7-8 years under a field setting. The 50 subjects were randomly allocated into two groups. Baseline plaque samples were collected from all the subjects followed by the application of two varnishes, Cervitec and Duraphat. The varnish was applied to pit and fissures of occlusal surface of mandibular first molar. The varnish application was carried out on the first day, fifth day and tenth day after baseline plaque sampling. Subsequent plaque samples were collected at the end of 1 month and at the end of 3 months after the varnish application. RESULTS: The Cervitec varnish has shown a statistically significant reduction at the end of 1 month and at the end of 3 months (P < 0.05). Duraphat varnish did not show a statistically significant difference in reducing the plaque S. mutans count at the end of 1 month and third month (P > 0.05). CONCLUSION:Cervitec varnish was found to be effective in reducing S. mutans count for a 3-month period, when compared to Duraphat varnish.
RCT Entities:
AIM: The aim of the study was to assess and compare the effect of chlorhexidine varnish and fluoride varnish application on Streptococcus mutans counts in plaque of occlusal pits and fissures of permanent mandibular first molars. MATERIALS AND METHODS: The study was an in vivo comparative study, conducted among 50 schoolchildren aged 7-8 years under a field setting. The 50 subjects were randomly allocated into two groups. Baseline plaque samples were collected from all the subjects followed by the application of two varnishes, Cervitec and Duraphat. The varnish was applied to pit and fissures of occlusal surface of mandibular first molar. The varnish application was carried out on the first day, fifth day and tenth day after baseline plaque sampling. Subsequent plaque samples were collected at the end of 1 month and at the end of 3 months after the varnish application. RESULTS: The Cervitec varnish has shown a statistically significant reduction at the end of 1 month and at the end of 3 months (P < 0.05). Duraphat varnish did not show a statistically significant difference in reducing the plaque S. mutans count at the end of 1 month and third month (P > 0.05). CONCLUSION: Cervitec varnish was found to be effective in reducing S. mutans count for a 3-month period, when compared to Duraphat varnish.
Authors: Leonardo Marchini; Erica Recker; Jennifer Hartshorn; Howard Cowen; David Lynch; David Drake; Derek R Blanchette; Deborah V Dawson; Michael Kanellis; Daniel Caplan Journal: Spec Care Dentist Date: 2018-09-08
Authors: Yun Fei Li; Hong Wu Sun; Rong Gao; Kai Yun Liu; Hua Qi Zhang; Qi Huan Fu; Sheng Li Qing; Gang Guo; Quan Ming Zou Journal: Int J Nanomedicine Date: 2015-01-09
Authors: Juçara R Franca; Mariana P De Luca; Tatiana G Ribeiro; Rachel O Castilho; Allyson N Moreira; Vagner R Santos; André A G Faraco Journal: BMC Complement Altern Med Date: 2014-12-12 Impact factor: 3.659