Literature DB >> 23715846

Acute MI in a young hypertensive woman: could it be due to tranexamic acid?

Prabha Nini Gupta1, Ullas R Mullamalla, P Sabin, Praveen Vellappan.   

Abstract

The case report illustrates an acute myocardial infarction (MI) in a 41-year-old hypertensive woman possibly because of an intake of a combination of tranexamic acid and mefenamic acid for dysmenorrhoea and menorrhagia. There are multiple case reports of MI occurring in the setting of the use of antifibrinolytic agents including tranexamic acid. The present case serves as a warning that, even in patients with an apparently low risk for arterial thrombosis, these drugs may be implicated as a precipitant of MI.

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Year:  2013        PMID： 23715846      PMCID： PMC3670019          DOI： 10.1136/bcr-2013-009979

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  4 in total

1.  Acute myocardial infarction following tranexamic acid use in a low cardiovascular risk setting.

Authors:  Alexander Sirker; Nikesh Malik; Michael Bellamy; Mike A Laffan
Journal:  Br J Haematol       Date:  2008-03-19       Impact factor: 6.998

2.  The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.

Authors:  Ian Roberts; Haleema Shakur; Adefemi Afolabi; Karim Brohi; Tim Coats; Yashbir Dewan; Satoshi Gando; Gordon Guyatt; B J Hunt; Carlos Morales; Pablo Perel; David Prieto-Merino; Tom Woolley
Journal:  Lancet       Date:  2011-03-26       Impact factor: 79.321

3.  Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) Trial: rationale and design.

Authors:  Paul S Myles; Julian Smith; John Knight; D James Cooper; Brendan Silbert; John McNeil; Donald S Esmore; Brian Buxton; Henry Krum; Andrew Forbes; Andrew Tonkin
Journal:  Am Heart J       Date:  2007-11-26       Impact factor: 4.749

Review 4.  Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.

Authors:  Katharine Ker; Phil Edwards; Pablo Perel; Haleema Shakur; Ian Roberts
Journal:  BMJ       Date:  2012-05-17
  4 in total
  2 in total

1.  Acute ST-elevation myocardial infarction due to in-stent thrombosis after administering tranexamic acid in a high cardiac risk patient.

Authors:  Yvonne E Kaptein
Journal:  BMJ Case Rep       Date:  2019-04-08

2.  High-Dose Tranexamic Acid in Patients Underwent Surgical Repair of Aortic Dissection Might Reduce Postoperative Blood Loss: A Cohort Analysis.

Authors:  Jingfei Guo; Liang Cao; Hongbai Wang; Guangyu Liu; Yong Zhou; Lijing Yang; Yuan Jia; Su Yuan
Journal:  Front Surg       Date:  2022-06-14
  2 in total

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