Literature DB >> 23714310

Drug-induced immune thrombocytopenia.

Beng H Chong1, Philip Young-Ill Choi, Levon Khachigian, Jose Perdomo.   

Abstract

Thrombocytopenia is caused by immune reactions elicited by diverse drugs in clinical practice. The activity of the drug-dependent antibodies produces a marked decrease in blood platelets and a risk of serious bleeding. Understanding of the cellular mechanisms that drive drug-induced thrombocytopenia has advanced recently but there is still a need for improved laboratory tests and treatment options. This article provides an overview of the different types of drug-induced thrombocytopenia, discusses potential pathologic mechanisms, and considers diagnostic methods and treatment options.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23714310     DOI: 10.1016/j.hoc.2013.02.003

Source DB:  PubMed          Journal:  Hematol Oncol Clin North Am        ISSN: 0889-8588            Impact factor:   3.722


  8 in total

1.  Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells.

Authors:  Jose Perdomo; Feng Yan; Halina H L Leung; Beng H Chong
Journal:  J Vis Exp       Date:  2017-12-27       Impact factor: 1.355

2.  Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies.

Authors:  Brian R Curtis; Yen-Michael S Hsu; Nikolai Podoltsev; Jill Lacy; Susanna Curtis; Michael S Samuel; Kristin Zutavern; Robert A DeSimone; Daniel W Bougie; Richard H Aster
Journal:  Blood       Date:  2018-02-12       Impact factor: 22.113

3.  Species-Specific Involvement of Integrin αIIbβ3 in a Monoclonal Antibody CH12 Triggers Off-Target Thrombocytopenia in Cynomolgus Monkeys.

Authors:  Yiting Zhang; Jianhua Sun; Minjia Tan; Yongzhen Liu; Qian Li; Hua Jiang; Huamao Wang; Zonghai Li; Wei Wan; Hualiang Jiang; Henglei Lu; Bingshun Wang; Jin Ren; Likun Gong
Journal:  Mol Ther       Date:  2018-04-07       Impact factor: 11.454

4.  Consensus guidelines for the management of adult immune thrombocytopenia in Australia and New Zealand.

Authors:  Philip Yi Choi; Eileen Merriman; Ashwini Bennett; Anoop K Enjeti; Chee Wee Tan; Isaac Goncalves; Danny Hsu; Robert Bird
Journal:  Med J Aust       Date:  2021-10-10       Impact factor: 12.776

Review 5.  Immunogenicity to Biotherapeutics - The Role of Anti-drug Immune Complexes.

Authors:  Murli Krishna; Steven G Nadler
Journal:  Front Immunol       Date:  2016-02-02       Impact factor: 7.561

Review 6.  A rare case report of acyclovir-induced immune thrombocytopenia with tongue hematomas as the first sign, and a literature review.

Authors:  Xiaowei Hong; Xiaoqian Wang; Zhiyong Wang
Journal:  BMC Pharmacol Toxicol       Date:  2017-03-07       Impact factor: 2.483

7.  Thrombin generation and platelet activation in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy - A prospective cohort study.

Authors:  Sven Van Poucke; Dana Huskens; Kurt Van der Speeten; Mark Roest; Bart Lauwereins; Ming-Hua Zheng; Seppe Dehaene; Joris Penders; Abraham Marcus; Marcus Lancé
Journal:  PLoS One       Date:  2018-06-21       Impact factor: 3.240

8.  Isolation of megakaryocytes using magnetic cell separation and adverse effects induced by diclofenac toxicity in an experiment.

Authors:  Irina Yuriivna Bagmut; Olexiy Sergiyovych Ivanov; Michael Ivanovich Sheremet; Sergiy Mykolayovych Smirnov; Igor Leonidovich Kolisnyk; Julia Viktorivna Ivanova; Mykhailo Yevgenievich Tymchenko; Vyacheslav Oleksievich Lazirskiy
Journal:  J Med Life       Date:  2022-01
  8 in total

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