Literature DB >> 23711677

The CXXC-TET bridge--mind the methylation gap!

Donncha S Dunican1, Sari Pennings, Richard R Meehan.   

Abstract

CG-rich DNA "reader" proteins that bind non-methylated CpG sequences have emerged as critical factors to the process of cell differentiation and development. In a recent paper in Nature, Ko et al. show that the CXXC domain protein, IDAX, plays a crucial role as a CG-rich DNA-binding factor in the regulation of Ten-Eleven-Translocation 2 (TET2) protein function.

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Year:  2013        PMID： 23711677      PMCID： PMC3731560          DOI： 10.1038/cr.2013.71

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.

Authors:  S Hino; S Kishida; T Michiue; A Fukui; I Sakamoto; S Takada; M Asashima; A Kikuchi
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

2.  Il2 transcription unleashed by active DNA demethylation.

Authors:  Adrian Bird
Journal:  Nat Immunol       Date:  2003-03       Impact factor: 25.606

Review 3.  CpG islands and the regulation of transcription.

Authors:  Aimée M Deaton; Adrian Bird
Journal:  Genes Dev       Date:  2011-05-15       Impact factor: 11.361

4.  Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.

Authors:  Jikui Song; Olga Rechkoblit; Timothy H Bestor; Dinshaw J Patel
Journal:  Science       Date:  2010-12-16       Impact factor: 47.728

Review 5.  DNA methylation and methylcytosine oxidation in cell fate decisions.

Authors:  Kian Peng Koh; Anjana Rao
Journal:  Curr Opin Cell Biol       Date:  2013-03-14       Impact factor: 8.382

6.  Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development.

Authors:  Yufei Xu; Chao Xu; Akiko Kato; Wolfram Tempel; Jose Garcia Abreu; Chuanbing Bian; Yeguang Hu; Di Hu; Bin Zhao; Tanja Cerovina; Jianbo Diao; Feizhen Wu; Housheng Hansen He; Qingyan Cui; Erin Clark; Chun Ma; Andrew Barbara; Gert Jan C Veenstra; Guoliang Xu; Ursula B Kaiser; X Shirley Liu; Stephen P Sugrue; Xi He; Jinrong Min; Yoichi Kato; Yujiang Geno Shi
Journal:  Cell       Date:  2012-12-07       Impact factor: 41.582

7.  Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Authors:  Mamta Tahiliani; Kian Peng Koh; Yinghua Shen; William A Pastor; Hozefa Bandukwala; Yevgeny Brudno; Suneet Agarwal; Lakshminarayan M Iyer; David R Liu; L Aravind; Anjana Rao
Journal:  Science       Date:  2009-04-16       Impact factor: 47.728

8.  Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Authors:  Myunggon Ko; Jungeun An; Hozefa S Bandukwala; Lukas Chavez; Tarmo Aijö; William A Pastor; Matthew F Segal; Huiming Li; Kian Peng Koh; Harri Lähdesmäki; Patrick G Hogan; L Aravind; Anjana Rao
Journal:  Nature       Date:  2013-04-07       Impact factor: 49.962

9.  The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways.

Authors:  Alexey Ruzov; Jamie A Hackett; Anna Prokhortchouk; James P Reddington; Monika J Madej; Donncha S Dunican; Egor Prokhortchouk; Sari Pennings; Richard R Meehan
Journal:  Development       Date:  2009-01-21       Impact factor: 6.868

Review 10.  Non-canonical functions of the DNA methylome in gene regulation.

Authors:  James P Reddington; Sari Pennings; Richard R Meehan
Journal:  Biochem J       Date:  2013-04-01       Impact factor: 3.857
  10 in total
  3 in total

Review 1.  Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation.

Authors:  Bodo C Melnik; Swen Malte John; Pedro Carrera-Bastos; Gerd Schmitz
Journal:  Clin Transl Allergy       Date:  2016-05-12       Impact factor: 5.871

Review 2.  Milk's Role as an Epigenetic Regulator in Health and Disease.

Authors:  Bodo C Melnik; Gerd Schmitz
Journal:  Diseases       Date:  2017-03-15

Review 3.  Milk: an exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy?

Authors:  Bodo C Melnik; Swen Malte John; Gerd Schmitz
Journal:  J Transl Med       Date:  2014-02-12       Impact factor: 5.531
  3 in total

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