OBJECTIVE: To assess the proportion of current implantable cardioverter defibrillator (ICD) recipients who would be suitable for a subcutaneous lead ICD (S-ICD). DESIGN: A retrospective cohort study. SETTING: Tertiary care facility in the Netherlands. PATIENTS: All patients who received a single- or dual-chamber ICD in the Leiden University Medical Center between 2002 and 2011. Patients with a pre-existent indication for cardiac pacing were excluded. MAIN OUTCOME MEASURE: Suitability for an S-ICD defined as not reaching one of the following endpoints during follow-up: (1) an atrial and/or right ventricular pacing indication, (2) successful antitachycardia pacing without a subsequent shock or (3) an upgrade to a CRT-D device. RESULTS: During a median follow-up of 3.4 years (IQR 1.7-5.7 years), 463 patients (34% of the total population of 1345 patients) reached an endpoint. The cumulative incidence of ICD recipients suitable for an initial S-ICD implantation was 55.5% (95% CI 52.0% to 59.0%) after 5 years. Significant predictors for the unsuitability of an S-ICD were: secondary prevention, severe heart failure and prolonged QRS duration. CONCLUSIONS: After 5 years of follow-up, approximately 55% of the patients would have been suitable for an S-ICD implantation. Several baseline clinical characteristics were demonstrated to be useful in the selection of patients suitable for an S-ICD implantation.
OBJECTIVE: To assess the proportion of current implantable cardioverter defibrillator (ICD) recipients who would be suitable for a subcutaneous lead ICD (S-ICD). DESIGN: A retrospective cohort study. SETTING: Tertiary care facility in the Netherlands. PATIENTS: All patients who received a single- or dual-chamber ICD in the Leiden University Medical Center between 2002 and 2011. Patients with a pre-existent indication for cardiac pacing were excluded. MAIN OUTCOME MEASURE: Suitability for an S-ICD defined as not reaching one of the following endpoints during follow-up: (1) an atrial and/or right ventricular pacing indication, (2) successful antitachycardia pacing without a subsequent shock or (3) an upgrade to a CRT-D device. RESULTS: During a median follow-up of 3.4 years (IQR 1.7-5.7 years), 463 patients (34% of the total population of 1345 patients) reached an endpoint. The cumulative incidence of ICD recipients suitable for an initial S-ICD implantation was 55.5% (95% CI 52.0% to 59.0%) after 5 years. Significant predictors for the unsuitability of an S-ICD were: secondary prevention, severe heart failure and prolonged QRS duration. CONCLUSIONS: After 5 years of follow-up, approximately 55% of the patients would have been suitable for an S-ICD implantation. Several baseline clinical characteristics were demonstrated to be useful in the selection of patients suitable for an S-ICD implantation.
Authors: Marcin Grabowski; Monika Gawałko; Marcin Michalak; Andrzej Cacko; Michał Kowara; Agnieszka Kołodzińska; Łukasz Januszkiewicz; Paweł Balsam; Laura Vitali Serdoz; Joachim Winter; Grzegorz Opolski Journal: Cardiol J Date: 2018-04-03 Impact factor: 2.737
Authors: Giovanni Luca Botto; Giovanni B Forleo; Alessandro Capucci; Francesco Solimene; Antonello Vado; Giovanni Bertero; Pietro Palmisano; Ennio Pisanò; Antonio Rapacciuolo; Tommaso Infusino; Alessandro Vicentini; Miguel Viscusi; Paola Ferrari; Antonello Talarico; Giovanni Russo; Giuseppe Boriani; Luigi Padeletti; Mariolina Lovecchio; Sergio Valsecchi; Antonio D'Onofrio Journal: Europace Date: 2017-11-01 Impact factor: 5.214