OBJECTIVE: To characterize the prevalence and distribution of genital human papillomavirus (HPV) types among women in Jamaica, and to explore risk factors associated with HPV infection. METHODS: This was a cross-sectional study that took place in April-July 2010 with 852 sexually-active women, 16-49 years of age, who had attended a selected public or private primary health clinic in one of Jamaica's four health authority regions. Sociodemographic data was collected from each participant by trained study staff. Each participant had a gynecological examination that included a clinical Pap test and a cervical sample for HPV detection and typing-performed using the Research Use Only Linear Array (LA) genotyping assay (Roche Diagnostics Corp., Indianapolis, Indiana, United States). Overall and type-specific prevalence of HPV infection was calculated for 37 HPV types included in the LA genotyping assay. RESULTS: HPV DNA was detected in 460 of the 852 women (54.0%). Oncogenic HPV was detected in 297 women (34.9%) and HPV types 16/18 were found in 86 women (10.1%). The most frequently occurring HPV types were: 16 (6.2%); 35 (6.0%); 62 and 83 (5.5%); 61 and 58 (5.4%); 84 (4.7%); 18 (4.3%); and, 66 and 81 (4.2%). HPV prevalence was highest among women who were single, young (16-19 years), and had had more than three sexual partners in their lifetime. CONCLUSIONS: These results, coupled with high rates of cervical cancer, support introducing HPV vaccines while maintaining and strengthening cervical cancer screening services. Policy decision-making that reflects these results is instrumental to establishing a comprehensive cervical cancer program in Jamaica.
OBJECTIVE: To characterize the prevalence and distribution of genital human papillomavirus (HPV) types among women in Jamaica, and to explore risk factors associated with HPV infection. METHODS: This was a cross-sectional study that took place in April-July 2010 with 852 sexually-active women, 16-49 years of age, who had attended a selected public or private primary health clinic in one of Jamaica's four health authority regions. Sociodemographic data was collected from each participant by trained study staff. Each participant had a gynecological examination that included a clinical Pap test and a cervical sample for HPV detection and typing-performed using the Research Use Only Linear Array (LA) genotyping assay (Roche Diagnostics Corp., Indianapolis, Indiana, United States). Overall and type-specific prevalence of HPV infection was calculated for 37 HPV types included in the LA genotyping assay. RESULTS:HPV DNA was detected in 460 of the 852 women (54.0%). Oncogenic HPV was detected in 297 women (34.9%) and HPV types 16/18 were found in 86 women (10.1%). The most frequently occurring HPV types were: 16 (6.2%); 35 (6.0%); 62 and 83 (5.5%); 61 and 58 (5.4%); 84 (4.7%); 18 (4.3%); and, 66 and 81 (4.2%). HPV prevalence was highest among women who were single, young (16-19 years), and had had more than three sexual partners in their lifetime. CONCLUSIONS: These results, coupled with high rates of cervical cancer, support introducing HPV vaccines while maintaining and strengthening cervical cancer screening services. Policy decision-making that reflects these results is instrumental to establishing a comprehensive cervical cancer program in Jamaica.
Authors: Adana A M Llanos; Wayne A Warner; Silvana Luciani; Tammy Y Lee; Smriti Bajracharya; Simeon Slovacek; Veronica Roach; Marjorie Lamont-Greene Journal: Cancer Causes Control Date: 2017-09-15 Impact factor: 2.506
Authors: K Mitchell-Fearon; D Willie-Tyndale; N Waldron; D Holder-Nevins; K James; H Laws; D Eldemire-Shearer Journal: Gerontol Geriatr Med Date: 2015-11-05
Authors: K Melan; E Janky; J Macni; S Ulric-Gervaise; M-J Dorival; J Veronique-Baudin; C Joachim Journal: Glob Health Action Date: 2017 Impact factor: 2.640
Authors: MacKinsey A Christian; Maureen Samms-Vaughan; MinJae Lee; Jan Bressler; Manouchehr Hessabi; Megan L Grove; Sydonnie Shakespeare-Pellington; Charlene Coore Desai; Jody-Ann Reece; Katherine A Loveland; Eric Boerwinkle; Mohammad H Rahbar Journal: J Autism Dev Disord Date: 2018-08
Authors: Desiree J Hooi; Birgit I Lissenberg-Witte; Maurits N C de Koning; Herbert M Pinedo; Gemma G Kenter; Chris Jlm Meijer; Wim G Quint Journal: Sex Transm Infect Date: 2017-10-11 Impact factor: 3.519
Authors: Desiree J Hooi; Birgit I Lissenberg-Witte; Gemma Kenter; Maurits N C de Koning; Igor Gomes Bravio; Kim Ardts; Suhaina Kleinmoedig; Edlyn Benita; Herbert M Pinedo; Johannes Berkhof; Wim G V Quint; Chris J L M Meijer Journal: PLoS One Date: 2018-07-13 Impact factor: 3.240