Literature DB >> 23695828

MORECare research methods guidance development: recommendations for ethical issues in palliative and end-of-life care research.

Marjolein Gysels1, Catherine J Evans, Penney Lewis, Peter Speck, Hamid Benalia, Nancy J Preston, Gunn E Grande, Vicky Short, Eleanor Owen-Jones, Chris J Todd, Irene J Higginson.   

Abstract

BACKGROUND: There is little guidance on the particular ethical concerns that research raises with a palliative care population. AIM: To present the process and outcomes of a workshop and consensus exercise on agreed best practice to accommodate ethical issues in research on palliative care.
DESIGN: Consultation workshop using the MORECare Transparent Expert Consultation approach. Prior to workshops, participants were sent overviews of ethical issues in palliative care. Following the workshop, nominal group techniques were used to produce candidate recommendations. These were rated online by participating experts. Descriptive statistics were used to analyse agreement and consensus. Narrative comments were collated. SETTING/PARTICIPANTS: Experts in ethical issues and palliative care research were invited to the Cicely Saunders Institute in London. They included senior researchers, service providers, commissioners, researchers, members of ethics committees and policy makers.
RESULTS: The workshop comprised 28 participants. A total of 16 recommendations were developed. There was high agreement on the issue of research participation and high to moderate agreement on applications to research ethics committees. The recommendations on obtaining and maintaining consent from patients and families were the most contentious. Nine recommendations were refined on the basis of the comments from the online consultation.
CONCLUSIONS: The culture surrounding palliative care research needs to change by fostering collaborative approaches between all those involved in the research process. Changes to the legal framework governing the research process are required to enhance the ethical conduct of research in palliative care. The recommendations are relevant to all areas of research involving vulnerable adults.

Entities:  

Keywords:  Ethics; consensus methods; end-of-life care; expert workshop; guidance development; online consultation; palliative care; research

Mesh:

Year:  2013        PMID: 23695828     DOI: 10.1177/0269216313488018

Source DB:  PubMed          Journal:  Palliat Med        ISSN: 0269-2163            Impact factor:   4.762


  27 in total

Review 1.  Ethical challenges and solutions regarding delirium studies in palliative care.

Authors:  Lisa Sweet; Dimitrios Adamis; David J Meagher; Daniel Davis; David C Currow; Shirley H Bush; Christopher Barnes; Michael Hartwick; Meera Agar; Jessica Simon; William Breitbart; Neil MacDonald; Peter G Lawlor
Journal:  J Pain Symptom Manage       Date:  2013-12-31       Impact factor: 3.612

Review 2.  Economic impact of hospital inpatient palliative care consultation: review of current evidence and directions for future research.

Authors:  Peter May; Charles Normand; R Sean Morrison
Journal:  J Palliat Med       Date:  2014-07-01       Impact factor: 2.947

Review 3.  End-of-life care--what do cancer patients want?

Authors:  Shaheen A Khan; Barbara Gomes; Irene J Higginson
Journal:  Nat Rev Clin Oncol       Date:  2013-11-26       Impact factor: 66.675

4.  Processes of consent in research for adults with impaired mental capacity nearing the end of life: systematic review and transparent expert consultation (MORECare_Capacity statement).

Authors:  C J Evans; E Yorganci; P Lewis; J Koffman; K Stone; I Tunnard; B Wee; W Bernal; M Hotopf; I J Higginson
Journal:  BMC Med       Date:  2020-07-22       Impact factor: 8.775

5.  Ethical conduct of palliative care research: enhancing communication between investigators and institutional review boards.

Authors:  Amy P Abernethy; Warren H Capell; Noreen M Aziz; Christine Ritchie; Maryjo Prince-Paul; Rachael E Bennett; Jean S Kutner
Journal:  J Pain Symptom Manage       Date:  2014-05-28       Impact factor: 3.612

6.  End-of-life care research with bereaved informal caregivers--analysis of recruitment strategy and participation rate from a multi-centre validation study.

Authors:  Stephanie Stiel; Maria Heckel; Sonja Bussmann; Martin Weber; Christoph Ostgathe
Journal:  BMC Palliat Care       Date:  2015-05-02       Impact factor: 3.234

7.  The selection and use of outcome measures in palliative and end-of-life care research: the MORECare International Consensus Workshop.

Authors:  Catherine J Evans; Hamid Benalia; Nancy J Preston; Gunn Grande; Marjolein Gysels; Vicky Short; Barbara A Daveson; Claudia Bausewein; Chris Todd; Irene J Higginson
Journal:  J Pain Symptom Manage       Date:  2013-04-28       Impact factor: 3.612

8.  The value of uncertainty in critical illness? An ethnographic study of patterns and conflicts in care and decision-making trajectories.

Authors:  I J Higginson; C Rumble; C Shipman; J Koffman; K E Sleeman; M Morgan; P Hopkins; J Noble; W Bernal; S Leonard; O Dampier; W Prentice; R Burman; M Costantini
Journal:  BMC Anesthesiol       Date:  2016-02-09       Impact factor: 2.217

9.  Results of a transparent expert consultation on patient and public involvement in palliative care research.

Authors:  Barbara A Daveson; Susanne de Wolf-Linder; Jana Witt; Kirstie Newson; Carolyn Morris; Irene J Higginson; Catherine J Evans
Journal:  Palliat Med       Date:  2015-04-30       Impact factor: 4.762

Review 10.  Evaluating complex interventions in end of life care: the MORECare statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews.

Authors:  Irene J Higginson; Catherine J Evans; Gunn Grande; Nancy Preston; Myfanwy Morgan; Paul McCrone; Penney Lewis; Peter Fayers; Richard Harding; Matthew Hotopf; Scott A Murray; Hamid Benalia; Marjolein Gysels; Morag Farquhar; Chris Todd
Journal:  BMC Med       Date:  2013-04-24       Impact factor: 8.775

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