Literature DB >> 23691566

[Toxic hepatitis induced by Polygonum multiflorum].

A Banarova1, T Koller, J Payer.   

Abstract

Toxic liver injury is a common cause of acute hepatitis. Here we report a case of 33-year old female with toxic hepatitis caused by unusual agent- extract of chinese plant Polygonum multiflorum. The patient presented with clinical signs of nausea and icterus and laboratory signs of hepatocellular damage following 2 months of readministration of Polygonum mulltiflorum pills. All other causes of hepatocellular damage were excluded. The causality between hepatocellular damage and Polygonum multiflorum ingestion was supported by early recovery after discontinuation, by international scoring system of causality between drug and hepatotoxicity as well as by similarities with other reports from the literature. Considering the growing popularity of herbal products as nutrition supplements we appeal to caution in using these preparations.

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Year:  2012        PMID: 23691566

Source DB:  PubMed          Journal:  Vnitr Lek        ISSN: 0042-773X


  11 in total

1.  Idiosyncratic drug-induced liver injury linked to Polygonum multiflorum: A case study by pharmacognosy.

Authors:  Chun-Yu Li; Qin He; Dan Gao; Rui-Yu Li; Yun Zhu; Hui-Fang Li; Wu-Wen Feng; Mei-Hua Yang; Xiao-He Xiao; Jia-Bo Wang
Journal:  Chin J Integr Med       Date:  2017-05-18       Impact factor: 1.978

2.  Acute hepatitis induced by a Chinese herbal product Qibao Meiran Wan: a case study.

Authors:  Xiaoyan Li; Caihong Qu; Qiong He; Wenying Chen; Xiaojuan Zhang; Xiaoqi Liu; Yuxing Liu; Yongbo Tang
Journal:  Int J Clin Exp Med       Date:  2015-07-15

Review 3.  Traditional Chinese Medicine (TCM) and Herbal Hepatotoxicity: RUCAM and the Role of Novel Diagnostic Biomarkers Such as MicroRNAs.

Authors:  Rolf Teschke; Dominique Larrey; Dieter Melchart; Gaby Danan
Journal:  Medicines (Basel)       Date:  2016-07-19

Review 4.  Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

Authors:  Rolf Teschke; Axel Eickhoff
Journal:  Front Pharmacol       Date:  2015-04-23       Impact factor: 5.810

Review 5.  Chinese Herbal Medicine-induced Liver Injury.

Authors:  Xin Ma; Jing-Hua Peng; Yi-Yang Hu
Journal:  J Clin Transl Hepatol       Date:  2014-09-15

Review 6.  Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds.

Authors:  Guy-Armel Bounda; Y U Feng
Journal:  Pharmacognosy Res       Date:  2015 Jul-Sep

Review 7.  Polygonum multiflorum-Induced Liver Injury: Clinical Characteristics, Risk Factors, Material Basis, Action Mechanism and Current Challenges.

Authors:  Yi Liu; Wenping Wang; Mingyi Sun; Baorui Ma; Linnuo Pang; Yuanyuan Du; Xiaoxv Dong; Xingbin Yin; Jian Ni
Journal:  Front Pharmacol       Date:  2019-12-13       Impact factor: 5.810

Review 8.  Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series.

Authors:  Xiang Lei; Jing Chen; Jingtian Ren; Yan Li; Jingbo Zhai; Wei Mu; Li Zhang; Wenke Zheng; Guihua Tian; Hongcai Shang
Journal:  Evid Based Complement Alternat Med       Date:  2015-01-12       Impact factor: 2.629

Review 9.  Herbal Hepatotoxicity: Clinical Characteristics and Listing Compilation.

Authors:  Christian Frenzel; Rolf Teschke
Journal:  Int J Mol Sci       Date:  2016-04-27       Impact factor: 5.923

Review 10.  Influence Factors on the Hepatotoxicity of Polygoni Multiflori Radix.

Authors:  Yun Wei; Meixia Liu; Jiangang Liu; Hao Li
Journal:  Evid Based Complement Alternat Med       Date:  2019-09-25       Impact factor: 2.629

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