Literature DB >> 23687168

Anastomotic leakage as an outcome measure for quality of colorectal cancer surgery.

H S Snijders1, D Henneman, N L van Leersum, M ten Berge, M Fiocco, T M Karsten, K Havenga, T Wiggers, J W Dekker, R A E M Tollenaar, M W J M Wouters.   

Abstract

INTRODUCTION: When comparing mortality rates between hospitals to explore hospital performance, there is an important role for adjustment for differences in case-mix. Identifying outcome measures that are less influenced by differences in case-mix may be valuable. The main goal of this study was to explore whether hospital differences in anastomotic leakage (AL) and postoperative mortality are due to differences in case-mix or to differences in treatment factors.
METHODS: Data of the Dutch Surgical Colorectal Audit were used. Case-mix factors and treatment-related factors were identified from the literature and their association with AL and mortality were analysed with logistic regression. Hospital differences in observed AL and mortality rates, and adjusted rates based on the logistic regression models were shown. The reduction in hospital variance after adjustment was analysed with Levene's test for equality of variances.
RESULTS: 17 of 22 case-mix factors and 4 of 11 treatment factors related to AL derived from the literature were available in the database. Variation in observed AL rates between hospitals was large with a maximum rate of 17%. This variation could not be attributed to differences in case-mix but more to differences in treatment factors. Hospital variation in observed mortality rates was significantly reduced after adjustment for differences in case-mix.
CONCLUSIONS: Hospital variation in AL is relatively independent of differences in case-mix. In contrast to 'postoperative mortality' the observed AL rates of hospitals evaluated in our study were only slightly affected after adjustment for case-mix factors. Therefore, AL rates may be suitable as an outcome indicator for measurement of surgical quality of care.

Entities:  

Keywords:  Audit and feedback; Mortality (standardized mortality ratios); Quality measurement; Surgery

Mesh:

Year:  2013        PMID: 23687168     DOI: 10.1136/bmjqs-2012-001644

Source DB:  PubMed          Journal:  BMJ Qual Saf        ISSN: 2044-5415            Impact factor:   7.035


  3 in total

Review 1.  Improving the outcomes in oncological colorectal surgery.

Authors:  Jeroen L A van Vugt; Kostan W Reisinger; Joep P M Derikx; Djamila Boerma; Jan H M B Stoot
Journal:  World J Gastroenterol       Date:  2014-09-21       Impact factor: 5.742

2.  AVOID; a phase III, randomised controlled trial using indocyanine green for the prevention of anastomotic leakage in colorectal surgery.

Authors:  Ruben P J Meijer; Robin A Faber; Okker D Bijlstra; Jeffrey P B M Braak; Elma Meershoek-Klein Kranenbarg; Hein Putter; J Sven D Mieog; Koos Burggraaf; Alexander L Vahrmeijer; Denise E Hilling
Journal:  BMJ Open       Date:  2022-04-01       Impact factor: 2.692

3.  Volume-outcome revisited: The effect of hospital and surgeon volumes on multiple outcome measures in oesophago-gastric cancer surgery.

Authors:  Claudia Fischer; Hester Lingsma; Niek Klazinga; Richard Hardwick; David Cromwell; Ewout Steyerberg; Oliver Groene
Journal:  PLoS One       Date:  2017-10-26       Impact factor: 3.240

  3 in total

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