Manuel Raya-Cruz1, Ignacio Ferullo2, María Arrizabalaga-Asenjo2, Antonio Nadal-Nadal3, María Paz Díaz-Antolín4, Margarita Garau-Colom4, Antonio Payeras-Cifre2. 1. Servicio de Medicina Interna y Enfermedades Infecciosas, Hospital Son Llàtzer, Palma de Mallorca, España. Electronic address: manuelraya@hotmail.com. 2. Servicio de Medicina Interna y Enfermedades Infecciosas, Hospital Son Llàtzer, Palma de Mallorca, España. 3. Servicio de Dermatología, Hospital Son Llàtzer, Palma de Mallorca, España. 4. Servicio de Microbiología Clínica, Hospital Son Llàtzer, Palma de Mallorca, España.
Abstract
INTRODUCTION: Skin and soft-tissue infections (SSTIs) are a frequent cause of consultation in emergence services, and complicated cases require hospitalization. However there are few data in our setting about the clinical characteristics of these infections. MATERIAL AND METHODS: A retrospective review of hospital admitted patients with a diagnosis of folliculitis, cellulitis, erysipelas, abscesses, hidradenitis, furuncle, impetigo, fasciitis and Fournier's gangrene. Cases were extracted from the data base of diagnostic codes of the Archive and Clinical Documentation Department of Son Llàtzer Hospital from January 2002 to November 2011. RESULTS: We studied 996 episodes in 841 hospitalized patients with any diagnosis of SSTIs. Cellulitis/erysipelas (66.7%) was the most frequently diagnosed condition, with 77% of all SSTIs being community acquired, and the majority of patients had comorbidities, mainly diabetes (33%) and heart failure (17.7%). The most frequent isolated microorganism was S.aureus (35.1%), in 19 (12.9%) cases with methicillin-resistance (MRSA), 84.2% of them were nosocomial or health care acquired. Monotherapy with aminopenicillin with clavulanic acid was the empiric treatment most frequently used (35.5%). New antibiotics for Gram-positive cocci (linezolid, daptomycin, and tigecycline) were used in patients with comorbidities that presented more complications (P<.001) and more risk of mortality (P=.001). During admission 10.9% of patients died, but only in 2.7% of them mortality was related to the SSTIs. CONCLUSIONS: SSTIs attended most frequently in hospitalized patients are mainly cellulitis/erysipela, the majority community acquired. MRSA infections are mainly health care related. Use of new antibiotic for Gram-positive cocci was limited.
INTRODUCTION: Skin and soft-tissue infections (SSTIs) are a frequent cause of consultation in emergence services, and complicated cases require hospitalization. However there are few data in our setting about the clinical characteristics of these infections. MATERIAL AND METHODS: A retrospective review of hospital admitted patients with a diagnosis of folliculitis, cellulitis, erysipelas, abscesses, hidradenitis, furuncle, impetigo, fasciitis and Fournier's gangrene. Cases were extracted from the data base of diagnostic codes of the Archive and Clinical Documentation Department of Son Llàtzer Hospital from January 2002 to November 2011. RESULTS: We studied 996 episodes in 841 hospitalized patients with any diagnosis of SSTIs. Cellulitis/erysipelas (66.7%) was the most frequently diagnosed condition, with 77% of all SSTIs being community acquired, and the majority of patients had comorbidities, mainly diabetes (33%) and heart failure (17.7%). The most frequent isolated microorganism was S.aureus (35.1%), in 19 (12.9%) cases with methicillin-resistance (MRSA), 84.2% of them were nosocomial or health care acquired. Monotherapy with aminopenicillin with clavulanic acid was the empiric treatment most frequently used (35.5%). New antibiotics for Gram-positive cocci (linezolid, daptomycin, and tigecycline) were used in patients with comorbidities that presented more complications (P<.001) and more risk of mortality (P=.001). During admission 10.9% of patients died, but only in 2.7% of them mortality was related to the SSTIs. CONCLUSIONS: SSTIs attended most frequently in hospitalized patients are mainly cellulitis/erysipela, the majority community acquired. MRSA infections are mainly health care related. Use of new antibiotic for Gram-positive cocci was limited.
Authors: Gustavo Lopes Gomes Siqueira; Ricardo Alves de Olinda; Camila Meira Barbosa de Siqueira; Analice Barros de Vasconcelos Sá Torres; Luana de Carvalho Viana Corrêa; Francisco de Assis Silva Lacerda; Pablo Luiz Fernandes Guimarães Journal: Ann Med Surg (Lond) Date: 2020-09-11
Authors: Julio Collazos; Belén de la Fuente; Alicia García; Helena Gómez; C Menéndez; Héctor Enríquez; Paula Sánchez; María Alonso; Ian López-Cruz; Manuel Martín-Regidor; Ana Martínez-Alonso; José Guerra; Arturo Artero; Marino Blanes; Javier de la Fuente; Víctor Asensi Journal: PLoS One Date: 2018-09-27 Impact factor: 3.240
Authors: J Collazos; B de la Fuente; J de la Fuente; A García; H Gómez; C Menéndez; H Enríquez; P Sánchez; M Alonso; I López-Cruz; M Martín-Regidor; A Martínez-Alonso; J Guerra; A Artero; M Blanes; V Asensi Journal: BMC Infect Dis Date: 2020-03-12 Impact factor: 3.090