Literature DB >> 23681969

Dual surface-functionalized Janus nanocomposites of polystyrene/Fe₃O₄@SiO₂ for simultaneous tumor cell targeting and stimulus-induced drug release.

Feng Wang1, Giovanni M Pauletti, Juntao Wang, Jiaming Zhang, Rodney C Ewing, Yilong Wang, Donglu Shi.   

Abstract

Folic acid (FA) and doxorubicin (DOX) are coupled separately onto Fe3 O4 @SiO2 and polystyrene surfaces of a unique polystyrene/Fe3 O4 @SiO2 Janus structure. This super-paramagnetic, dual-functionalized Janus nanocomposite enables effective tumor cell targeting and internalization via the folate receptor, and induces significant cancer cell death by controlled, stimulus-induced drug release under acidic conditions in endosomal compartments.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Janus nanocomposites; drug delivery; dual-functionality; targeting

Mesh：

Substances：

Year:  2013        PMID： 23681969     DOI： 10.1002/adma.201301376

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  23 in total

Review 1.  Janus particles for biological imaging and sensing.

Authors:  Yi Yi; Lucero Sanchez; Yuan Gao; Yan Yu
Journal:  Analyst       Date:  2016-04-07       Impact factor: 4.616

2.  Fe3O4 Nanoparticles: Structures, Synthesis, Magnetic Properties, Surface Functionalization, and Emerging Applications.

Authors:  Minh Dang Nguyen; Hung-Vu Tran; Shoujun Xu; T Randall Lee
Journal:  Appl Sci (Basel)       Date:  2021-11-29       Impact factor: 2.838

3.  Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing.

Authors:  Alexander H Mo; Preston B Landon; Karla Santacruz Gomez; Heemin Kang; Joon Lee; Chen Zhang; Woraphong Janetanakit; Vrinda Sant; Tianyu Lu; David A Colburn; Siddhartha Akkiraju; Samuel Dossou; Yue Cao; Kuo-Fen Lee; Shyni Varghese; Gennadi Glinsky; Ratnesh Lal
Journal:  Nanoscale       Date:  2016-06-09       Impact factor: 7.790

4.  Bioinspired Polymeric High Aspect Ratio Particles with Asymmetric Janus Functionalities.

Authors:  Joel A Finbloom; Yiqi Cao; Tejal A Desai
Journal:  Adv Nanobiomed Res       Date:  2021-02-17

5.  Magnetically targeted co-delivery of hydrophilic and hydrophobic drugs with hollow mesoporous ferrite nanoparticles.

Authors:  Chao Xu; Suchun Yu; Langlang Liu; Xiaopei Wu; Honglian Dai
Journal:  RSC Adv       Date:  2018-04-23       Impact factor: 4.036

Review 6.  Mesoporous silica nanoparticles for stimuli-responsive controlled drug delivery: advances, challenges, and outlook.

Authors:  Yuanhui Song; Yihong Li; Qien Xu; Zhe Liu
Journal:  Int J Nanomedicine       Date:  2016-12-20

Review 7.  Nanoparticle Delivery Systems with Cell-Specific Targeting for Pulmonary Diseases.

Authors:  Zicheng Deng; Gregory T Kalin; Donglu Shi; Vladimir V Kalinichenko
Journal:  Am J Respir Cell Mol Biol       Date:  2021-03       Impact factor: 6.914

Review 8.  Magnetic Nanoparticle Composites: Synergistic Effects and Applications.

Authors:  Stefanos Mourdikoudis; Athanasia Kostopoulou; Alec P LaGrow
Journal:  Adv Sci (Weinh)       Date:  2021-05-05       Impact factor: 16.806

9.  Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes.

Authors:  Bingdi Chen; Wenjun Le; Yilong Wang; Zhuoquan Li; Dong Wang; Lei Ren; Ling Lin; Shaobin Cui; Jennifer J Hu; Yihui Hu; Pengyuan Yang; Rodney C Ewing; Donglu Shi; Zheng Cui
Journal:  Theranostics       Date:  2016-08-07       Impact factor: 11.556

10.  Multifunctional PMMA@Fe₃O₄@DR Magnetic Materials for Efficient Adsorption of Dyes.

Authors:  Bing Yu; Liang He; Yifan Wang; Hailin Cong
Journal:  Materials (Basel)       Date:  2017-10-27       Impact factor: 3.623
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