Literature DB >> 23680142

Luring BRCA1 to the scene of the crime.

Richard Baer1.   

Abstract

To preserve genome stability, BRCA1 must be recruited to sites of DNA damage, where BRCA1 facilitates repair of double-strand DNA breaks (DSBs). In this issue of Cancer Cell, Li and Yu report that BRCA1 recruitment involves a novel interaction between its partner protein BARD1 and poly(ADP-ribose) chains at the DSB.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 23680142      PMCID： PMC3746756          DOI： 10.1016/j.ccr.2013.04.013

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

Authors:  Niels Mailand; Simon Bekker-Jensen; Helene Faustrup; Fredrik Melander; Jiri Bartek; Claudia Lukas; Jiri Lukas
Journal:  Cell       Date:  2007-11-20       Impact factor: 41.582

Review 2.  PARP inhibition: PARP1 and beyond.

Authors:  Michèle Rouleau; Anand Patel; Michael J Hendzel; Scott H Kaufmann; Guy G Poirier
Journal:  Nat Rev Cancer       Date:  2010-03-04       Impact factor: 60.716

3.  Identification of a RING protein that can interact in vivo with the BRCA1 gene product.

Authors:  L C Wu; Z W Wang; J T Tsan; M A Spillman; A Phung; X L Xu; M C Yang; L Y Hwang; A M Bowcock; R Baer
Journal:  Nat Genet       Date:  1996-12       Impact factor: 38.330

4.  Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.

Authors:  Arkady Celeste; Oscar Fernandez-Capetillo; Michael J Kruhlak; Duane R Pilch; David W Staudt; Alicia Lee; Robert F Bonner; William M Bonner; André Nussenzweig
Journal:  Nat Cell Biol       Date:  2003-07       Impact factor: 28.824

5.  The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.

Authors:  Reena Shakya; Matthias Szabolcs; Ellen McCarthy; Elson Ospina; Katia Basso; Subhadra Nandula; Vundavalli Murty; Richard Baer; Thomas Ludwig
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-28       Impact factor: 11.205

Review 6.  Links between genome integrity and BRCA1 tumor suppression.

Authors:  Mischa L Li; Roger A Greenberg
Journal:  Trends Biochem Sci       Date:  2012-07-24       Impact factor: 13.807

7.  Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families.

Authors:  Sylvia De Brakeleer; Jacques De Grève; Remy Loris; Nicolas Janin; Willy Lissens; Erica Sermijn; Erik Teugels
Journal:  Hum Mutat       Date:  2010-03       Impact factor: 4.878

Review 8.  The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings.

Authors:  Thomas Helleday
Journal:  Mol Oncol       Date:  2011-07-22       Impact factor: 7.449

9.  Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.

Authors:  Simon Bekker-Jensen; Claudia Lukas; Risa Kitagawa; Fredrik Melander; Michael B Kastan; Jiri Bartek; Jiri Lukas
Journal:  J Cell Biol       Date:  2006-04-17       Impact factor: 10.539
  9 in total
  6 in total

1.  Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect.

Authors:  Tereza Vaclová; Nicholas T Woods; Diego Megías; Sergio Gomez-Lopez; Fernando Setién; José María García Bueno; José Antonio Macías; Alicia Barroso; Miguel Urioste; Manel Esteller; Alvaro N A Monteiro; Javier Benítez; Ana Osorio
Journal:  Hum Mol Genet       Date:  2016-12-15       Impact factor: 6.150

2.  Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women.

Authors:  Julie R Palmer; Eric C Polley; Chunling Hu; Esther M John; Christopher Haiman; Steven N Hart; Mia Gaudet; Tuya Pal; Hoda Anton-Culver; Amy Trentham-Dietz; Leslie Bernstein; Christine B Ambrosone; Elisa V Bandera; Kimberly A Bertrand; Traci N Bethea; Chi Gao; Rohan D Gnanaolivu; Hongyan Huang; Kun Y Lee; Loic LeMarchand; Jie Na; Dale P Sandler; Payal D Shah; Siddhartha Yadav; William Yang; Jeffrey N Weitzel; Susan M Domchek; David E Goldgar; Katherine L Nathanson; Peter Kraft; Song Yao; Fergus J Couch
Journal:  J Natl Cancer Inst       Date:  2020-12-14       Impact factor: 13.506

3.  Inherited predisposition to breast cancer among African American women.

Authors:  Jane E Churpek; Tom Walsh; Yonglan Zheng; Zakiya Moton; Anne M Thornton; Ming K Lee; Silvia Casadei; Amanda Watts; Barbara Neistadt; Matthew M Churpek; Dezheng Huo; Cecilia Zvosec; Fang Liu; Qun Niu; Rafael Marquez; Jing Zhang; James Fackenthal; Mary-Claire King; Olufunmilayo I Olopade
Journal:  Breast Cancer Res Treat       Date:  2014-11-27       Impact factor: 4.872

4.  The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.

Authors:  Mo Li; Lin-Yu Lu; Chao-Yie Yang; Shaomeng Wang; Xiaochun Yu
Journal:  Genes Dev       Date:  2013-08-15       Impact factor: 11.361

Review 5.  The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy.

Authors:  M Li; X Yu
Journal:  Oncogene       Date:  2014-09-15       Impact factor: 9.867

6.  The Impact of the Deepwater Horizon Oil Spill upon Lung Health-Mouse Model-Based RNA-Seq Analyses.

Authors:  Yao-Zhong Liu; Charles A Miller; Yan Zhuang; Sudurika S Mukhopadhyay; Shigeki Saito; Edward B Overton; Gilbert F Morris
Journal:  Int J Environ Res Public Health       Date:  2020-07-29       Impact factor: 3.390
  6 in total

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