Literature DB >> 23678364

Promise of endothelial progenitor cell for treatment of diabetic retinopathy.

Ashay D Bhatwadekar1, Lynn C Shaw, Maria B Grant.   

Abstract

Progressive obliteration of the retinal microvessels is a characteristic of diabetic retinopathy. The resultant retinal ischemia leads to sight-threatening neovascularization and macular edema. Bone marrow-derived endothelial progenitor cells play a critical role in vascular maintenance and repair and forms the basis of cellular therapy for revascularization of ischemic myocardium and ischemic limbs. Emerging studies show potential of these cells in revascularization of ischemic retina and this review summarizes this possibility. We also report current pharmacological options to correct diabetes-associated defects in endothelial progenitor cells for their therapeutic transfer.

Entities:  

Keywords:  diabetic retinopathy; endothelial nitric oxide synthase; endothelial progenitor cell

Year:  2010        PMID： 23678364      PMCID： PMC3652409          DOI： 10.1586/eem.09.75

Source DB:  PubMed          Journal:  Expert Rev Endocrinol Metab        ISSN： 1744-6651


  83 in total

1.  Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells.

Authors:  Alexis S Bailey; Shuguang Jiang; Michael Afentoulis; Christina I Baumann; David A Schroeder; Susan B Olson; Melissa H Wong; William H Fleming
Journal:  Blood       Date:  2003-09-04       Impact factor: 22.113

2.  Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases.

Authors:  Chang-Hwan Yoon; Jin Hur; Kyung-Woo Park; Ji-Hyun Kim; Choon-Soo Lee; Il-Young Oh; Tae-Youn Kim; Hyun-Jai Cho; Hyun-Jae Kang; In-Ho Chae; Han-Kwang Yang; Byung-Hee Oh; Young-Bae Park; Hyo-Soo Kim
Journal:  Circulation       Date:  2005-09-06       Impact factor: 29.690

3.  Differentiation of bone marrow-derived endothelial progenitor cells is shifted into a proinflammatory phenotype by hyperglycemia.

Authors:  Cindy Jm Loomans; Rien van Haperen; Jacques M Duijs; Caroline Verseyden; Rini de Crom; Pieter Jm Leenen; Hemmo A Drexhage; Hetty C de Boer; Eelco Jp de Koning; Ton J Rabelink; Frank Jt Staal; Anton Jan van Zonneveld
Journal:  Mol Med       Date:  2009-03-11       Impact factor: 6.354

4.  Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.

Authors:  Csaba Szabó; Jon G Mabley; Suzanne M Moeller; Roman Shimanovich; Pál Pacher; László Virag; Francisco G Soriano; John H Van Duzer; William Williams; Andrew L Salzman; John T Groves
Journal:  Mol Med       Date:  2002-10       Impact factor: 6.354

5.  In vitro differentiation of endothelial cells from AC133-positive progenitor cells.

Authors:  U M Gehling; S Ergün; U Schumacher; C Wagener; K Pantel; M Otte; G Schuch; P Schafhausen; T Mende; N Kilic; K Kluge; B Schäfer; D K Hossfeld; W Fiedler
Journal:  Blood       Date:  2000-05-15       Impact factor: 22.113

6.  Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat.

Authors:  E Ann Ellis; Dennis L Guberski; Brenda Hutson; Maria B Grant
Journal:  Nitric Oxide       Date:  2002-05       Impact factor: 4.427

7.  Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial.

Authors:  Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Nikos Werner; Jürgen Haase; Jörg Neuzner; Alfried Germing; Bernd Mark; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Journal:  Eur Heart J       Date:  2006-11-10       Impact factor: 29.983

8.  Inhibition of iNOS augments cardiovascular action of noradrenaline in streptozotocin-induced diabetes.

Authors:  Xing Cheng; Xiao Shuo Cheng; Kuo-Hsing Kuo; Catherine C Y Pang
Journal:  Cardiovasc Res       Date:  2004-11-01       Impact factor: 10.787

9.  Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

Authors:  T Münzel; H Sayegh; B A Freeman; M M Tarpey; D G Harrison
Journal:  J Clin Invest       Date:  1995-01       Impact factor: 14.808

10.  Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment.

Authors:  Olaia Naveiras; Valentina Nardi; Pamela L Wenzel; Peter V Hauschka; Frederic Fahey; George Q Daley
Journal:  Nature       Date:  2009-06-10       Impact factor: 49.962
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  6 in total

1.  Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia.

Authors:  Xiaozhen Dai; Xiaoqing Yan; Jun Zeng; Jing Chen; Yuehui Wang; Jun Chen; Yan Li; Michelle T Barati; Kupper A Wintergerst; Kejian Pan; Matthew A Nystoriak; Daniel J Conklin; Gregg Rokosh; Paul N Epstein; Xiaokun Li; Yi Tan
Journal:  Circ Res       Date:  2017-01-30       Impact factor: 17.367

Review 2.  The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding.

Authors:  Sarah X Zhang; Jacey H Ma; Maulasri Bhatta; Steven J Fliesler; Joshua J Wang
Journal:  Prog Retin Eye Res       Date:  2014-12-18       Impact factor: 21.198

3.  Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy.

Authors:  Qi Wang; Svetlana Navitskaya; Harshini Chakravarthy; Chao Huang; Nermin Kady; Todd A Lydic; Y Eugene Chen; Ke-Jie Yin; Folami Lamoke Powell; Pamela M Martin; Maria B Grant; Julia V Busik
Journal:  EBioMedicine       Date:  2016-08-08       Impact factor: 8.143

4.  Synergistic effect of VEGF and SDF-1α in endothelial progenitor cells and vascular smooth muscle cells.

Authors:  Haiyan Yang; Cancan He; Yang Bi; Xu Zhu; Dan Deng; Tingting Ran; Xiaojuan Ji
Journal:  Front Pharmacol       Date:  2022-07-15       Impact factor: 5.988

5.  Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina.

Authors:  Ping Hu; Nicholas H Hunt; Frank Arfuso; Lynn C Shaw; Mohammad Nasir Uddin; Meidong Zhu; Raj Devasahayam; Samuel J Adamson; Vicky L Benson; Tailoi Chan-Ling; Maria B Grant
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-10-01       Impact factor: 4.799

6.  Nrf2 protects against diabetic dysfunction of endothelial progenitor cells via regulating cell senescence.

Authors:  Rui-Yun Wang; Li-Hua Liu; Hongxia Liu; Ke-Fei Wu; Jing An; Qian Wang; Yun Liu; Li-Juan Bai; Ben-Ming Qi; Ben-Ling Qi; Lei Zhang
Journal:  Int J Mol Med       Date:  2018-06-11       Impact factor: 4.101
  6 in total

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