Literature DB >> 23675711

Recombinant human activated protein C as a therapy for severe sepsis: lessons learned?

Steven M Opal, Steven P LaRosa.   

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Year:  2013        PMID： 23675711     DOI： 10.1164/rccm.201303-0505ED

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  10 in total

1.  Intensive care in 2050: healthcare expenditure.

Authors:  B Guidet; P H J van der Voort; A Csomos
Journal:  Intensive Care Med       Date:  2017-02-01       Impact factor: 17.440

2.  Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation.

Authors:  Emily P Mihalko; Megan Sandry; Nicholas Mininni; Kimberly Nellenbach; Halston Deal; Michael Daniele; Kamrouz Ghadimi; Jerrold H Levy; Ashley C Brown
Journal:  Blood Adv       Date:  2021-02-09

3.  A multibiomarker-based outcome risk stratification model for adult septic shock*.

Authors:  Hector R Wong; Christopher J Lindsell; Ville Pettilä; Nuala J Meyer; Simone A Thair; Sari Karlsson; James A Russell; Christopher D Fjell; John H Boyd; Esko Ruokonen; Michael G S Shashaty; Jason D Christie; Kimberly W Hart; Patrick Lahni; Keith R Walley
Journal:  Crit Care Med       Date:  2014-04       Impact factor: 7.598

4.  Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury.

Authors:  Ronald Carnemolla; Carlos H Villa; Colin F Greineder; Sergei Zaitsev; Kruti R Patel; M Anna Kowalska; Dmitriy N Atochin; Douglas B Cines; Don L Siegel; Charles T Esmon; Vladimir R Muzykantov
Journal:  FASEB J       Date:  2016-11-11       Impact factor: 5.191

Review 5.  Targeting the host hemostatic system function in bacterial infection for antimicrobial therapies.

Authors:  Yuanxi Xu; Haiqing Yu; Hongmin Sun
Journal:  J Thromb Thrombolysis       Date:  2014-01       Impact factor: 2.300

6.  Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect.

Authors:  Colin F Greineder; Jacob B Brenza; Ronald Carnemolla; Sergei Zaitsev; Elizabeth D Hood; Daniel C Pan; Bi-Sen Ding; Charles T Esmon; Ann Marie Chacko; Vladimir R Muzykantov
Journal:  FASEB J       Date:  2015-05-07       Impact factor: 5.191

7.  Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia.

Authors:  Johannes Daan de Boer; Liesbeth M Kager; Joris J T H Roelofs; Joost C M Meijers; Onno J de Boer; Hartmut Weiler; Berend Isermann; Cornelis van 't Veer; Tom van der Poll
Journal:  BMC Infect Dis       Date:  2014-11-04       Impact factor: 3.090

8.  Recombinant Activated Protein C (rhAPC) Affects Lipopolysaccharide-Induced Mechanical Compliance Changes and Beat Frequency of mESC-Derived Cardiomyocyte Monolayers.

Authors:  Aysegül Temiz Artmann; Eylem Kurulgan Demirci; Ipek Seda Fırat; Hakan Oflaz; Gerhard M Artmann
Journal:  Shock       Date:  2022-04-01       Impact factor: 3.454

Review 9.  The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer?

Authors:  Jonathan S Boomer; Jonathan M Green; Richard S Hotchkiss
Journal:  Virulence       Date:  2013-09-25       Impact factor: 5.882

Review 10.  Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases.

Authors:  Athina Savva; Thierry Roger
Journal:  Front Immunol       Date:  2013-11-18       Impact factor: 7.561
  10 in total

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