Literature DB >> 23673134

Are randomized trials obsolete or more important than ever in the genomic era?

John Pa Ioannidis1, Muin J Khoury2.   

Abstract

Entities:  

Year:  2013        PMID： 23673134      PMCID： PMC3707036          DOI： 10.1186/gm436

Source DB:  PubMed          Journal:  Genome Med        ISSN： 1756-994X            Impact factor:   11.117


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  8 in total

1.  Improving validation practices in "omics" research.

Authors:  John P A Ioannidis; Muin J Khoury
Journal:  Science       Date:  2011-12-02       Impact factor: 47.728

2.  A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions.

Authors:  A Cecile J W Janssens; Marta Gwinn; Linda A Bradley; Ben A Oostra; Cornelia M van Duijn; Muin J Khoury
Journal:  Am J Hum Genet       Date:  2008-03       Impact factor: 11.025

Review 3.  The use of genomics in clinical trial design.

Authors:  Richard Simon
Journal:  Clin Cancer Res       Date:  2008-10-01       Impact factor: 12.531

4.  Mega-trials for blockbusters.

Authors:  John P A Ioannidis
Journal:  JAMA       Date:  2013-01-16       Impact factor: 56.272

5.  Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial.

Authors:  Jason D Roberts; George A Wells; Michel R Le May; Marino Labinaz; Chris Glover; Michael Froeschl; Alexander Dick; Jean-Francois Marquis; Edward O'Brien; Sandro Goncalves; Irena Druce; Alexandre Stewart; Michael H Gollob; Derek Y F So
Journal:  Lancet       Date:  2012-03-29       Impact factor: 79.321

6.  The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?

Authors:  Elizabeth O Lillie; Bradley Patay; Joel Diamant; Brian Issell; Eric J Topol; Nicholas J Schork
Journal:  Per Med       Date:  2011-03       Impact factor: 2.512

Review 7.  Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine.

Authors:  Elliott Antman; Scott Weiss; Joseph Loscalzo
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2012-05-11

8.  HLA-B*5701 screening for hypersensitivity to abacavir.

Authors:  Simon Mallal; Elizabeth Phillips; Giampiero Carosi; Jean-Michel Molina; Cassy Workman; Janez Tomazic; Eva Jägel-Guedes; Sorin Rugina; Oleg Kozyrev; Juan Flores Cid; Phillip Hay; David Nolan; Sara Hughes; Arlene Hughes; Susanna Ryan; Nicholas Fitch; Daren Thorborn; Alastair Benbow
Journal:  N Engl J Med       Date:  2008-02-07       Impact factor: 91.245
  8 in total
  11 in total

1.  Medicine. Big data meets public health.

Authors:  Muin J Khoury; John P A Ioannidis
Journal:  Science       Date:  2014-11-28       Impact factor: 47.728

2.  The Application of Genomics in Diabetes: Barriers to Discovery and Implementation.

Authors:  James S Floyd; Bruce M Psaty
Journal:  Diabetes Care       Date:  2016-11       Impact factor: 19.112

Review 3.  [Evidence-based trauma and orthopedic surgery : 20 years after Sackett].

Authors:  D Stengel; S Kirschner; A Ekkernkamp; C Bartl
Journal:  Unfallchirurg       Date:  2016-09       Impact factor: 1.000

Review 4.  Personalized medicine: Genetic risk prediction of drug response.

Authors:  Ge Zhang; Daniel W Nebert
Journal:  Pharmacol Ther       Date:  2017-02-14       Impact factor: 12.310

5.  Guidance for pharmacogenomic biomarker testing in labels of FDA-approved drugs.

Authors:  Alexandre Vivot; Isabelle Boutron; Philippe Ravaud; Raphaël Porcher
Journal:  Genet Med       Date:  2014-12-18       Impact factor: 8.822

6.  What is translational genomics? An expanded research agenda for improving individual and population health.

Authors:  Sheri D Schully; Muin J Khoury
Journal:  Appl Transl Genom       Date:  2014-12

Review 7.  The ethics of clinical trials.

Authors:  Cecilia Nardini
Journal:  Ecancermedicalscience       Date:  2014-01-16

Review 8.  Issues surrounding the health economic evaluation of genomic technologies.

Authors:  James Buchanan; Sarah Wordsworth; Anna Schuh
Journal:  Pharmacogenomics       Date:  2013-11       Impact factor: 2.533

9.  Big data are coming to psychiatry: a general introduction.

Authors:  Scott Monteith; Tasha Glenn; John Geddes; Michael Bauer
Journal:  Int J Bipolar Disord       Date:  2015-09-29

10.  Evidence synthesis and guideline development in genomic medicine: current status and future prospects.

Authors:  Sheri D Schully; Tram Kim Lam; W David Dotson; Christine Q Chang; Naomi Aronson; Marian L Birkeland; Stephanie Jo Brewster; Stefania Boccia; Adam H Buchanan; Ned Calonge; Kathleen Calzone; Benjamin Djulbegovic; Katrina A B Goddard; Roger D Klein; Teri E Klein; Joseph Lau; Rochelle Long; Gary H Lyman; Rebecca L Morgan; Christina G S Palmer; Mary V Relling; Wendy S Rubinstein; Jesse J Swen; Sharon F Terry; Marc S Williams; Muin J Khoury
Journal:  Genet Med       Date:  2014-06-19       Impact factor: 8.822
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