Literature DB >> 23671007

Concise drug review: azacitidine and decitabine.

Ellen J B Derissen1, Jos H Beijnen, Jan H M Schellens.   

Abstract

Entities:  

Keywords:  Azacitidine; DNA methyltransferase inhibitor; Decitabine; Drug profile; Hypomethylating drug

Mesh：

Substances：

Year:  2013        PMID： 23671007      PMCID： PMC3662854          DOI： 10.1634/theoncologist.2012-0465

Source DB:  PubMed          Journal:  Oncologist        ISSN： 1083-7159


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  39 in total

1.  Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes.

Authors:  Guido Marcucci; Lewis Silverman; Mark Eller; Linda Lintz; C L Beach
Journal:  J Clin Pharmacol       Date:  2005-05       Impact factor: 3.126

2.  Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients.

Authors:  Björn Rüter; Pierre W Wijermans; Michael Lübbert
Journal:  Cancer       Date:  2006-04-15       Impact factor: 6.860

3.  Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B.

Authors:  Lewis R Silverman; David R McKenzie; Bercedis L Peterson; James F Holland; Jay T Backstrom; C L Beach; Richard A Larson
Journal:  J Clin Oncol       Date:  2006-08-20       Impact factor: 44.544

4.  Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia.

Authors:  Bruce D Cheson; Peter L Greenberg; John M Bennett; Bob Lowenberg; Pierre W Wijermans; Stephen D Nimer; Antonio Pinto; Miloslav Beran; Theo M de Witte; Richard M Stone; Moshe Mittelman; Guillermo F Sanz; Steven D Gore; Charles A Schiffer; Hagop Kantarjian
Journal:  Blood       Date:  2006-04-11       Impact factor: 22.113

5.  Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography.

Authors:  Ming Zhao; Michelle A Rudek; Ping He; Carol Hartke; Steve Gore; Michael A Carducci; Sharyn D Baker
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2004-12-25       Impact factor: 3.205

Review 6.  Intensive chemotherapy for patients with high-risk myelodysplastic syndrome.

Authors:  M Beran
Journal:  Int J Hematol       Date:  2000-08       Impact factor: 2.490

7.  The disposition and pharmacokinetics in humans of 5-azacytidine administered intravenously as a bolus or by continuous infusion.

Authors:  Z H Israili; W R Vogler; E S Mingioli; J L Pirkle; R W Smithwick; J H Goldstein
Journal:  Cancer Res       Date:  1976-04       Impact factor: 12.701

8.  Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study.

Authors:  Hagop Kantarjian; Jean-Pierre J Issa; Craig S Rosenfeld; John M Bennett; Maher Albitar; John DiPersio; Virginia Klimek; James Slack; Carlos de Castro; Farhad Ravandi; Richard Helmer; Lanlan Shen; Stephen D Nimer; Richard Leavitt; Azra Raza; Hussain Saba
Journal:  Cancer       Date:  2006-04-15       Impact factor: 6.860

9.  Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes.

Authors:  Mikkael A Sekeres; Ramon V Tiu; Rami Komrokji; Jeffrey Lancet; Anjali S Advani; Manuel Afable; Ricki Englehaupt; Joyce Juersivich; David Cuthbertson; Jennifer Paleveda; Ali Tabarroki; Valeria Visconte; Hideki Makishima; Andres Jerez; Ronald Paquette; Alan F List; Jaroslaw P Maciejewski
Journal:  Blood       Date:  2012-08-22       Impact factor: 22.113

Review 10.  5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

Authors:  Judith K Christman
Journal:  Oncogene       Date:  2002-08-12       Impact factor: 9.867
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1.  Epigenetic Regulation in Breast Cancer.

Authors:  Hye Jin Nam; Sung Hee Baek
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 2.  Prostate Cancer Epigenetics: From Basic Mechanisms to Clinical Implications.

Authors:  Srinivasan Yegnasubramanian; Angelo M De Marzo; William G Nelson
Journal:  Cold Spring Harb Perspect Med       Date:  2019-04-01       Impact factor: 6.915

3.  DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine.

Authors:  Jia Yu; Bo Qin; Ann M Moyer; Somaira Nowsheen; Tongzheng Liu; Sisi Qin; Yongxian Zhuang; Duan Liu; Shijia W Lu; Krishna R Kalari; Daniel W Visscher; John A Copland; Sarah A McLaughlin; Alvaro Moreno-Aspitia; Donald W Northfelt; Richard J Gray; Zhenkun Lou; Vera J Suman; Richard Weinshilboum; Judy C Boughey; Matthew P Goetz; Liewei Wang
Journal:  J Clin Invest       Date:  2018-04-30       Impact factor: 14.808

Review 4.  DNA Hypomethylating Drugs in Cancer Therapy.

Authors:  Takahiro Sato; Jean-Pierre J Issa; Patricia Kropf
Journal:  Cold Spring Harb Perspect Med       Date:  2017-05-01       Impact factor: 6.915

Review 5.  Therapeutic Approaches for Zika Virus Infection of the Nervous System.

Authors:  Rachel P M Abrams; Jamie Solis; Avindra Nath
Journal:  Neurotherapeutics       Date:  2017-10       Impact factor: 7.620

6.  Precision DNA demethylation ameliorates disease in lupus-prone mice.

Authors:  Hao Li; Maria G Tsokos; Sean Bickerton; Amir Sharabi; Yi Li; Vaishali R Moulton; Philip Kong; Tarek M Fahmy; George C Tsokos
Journal:  JCI Insight       Date:  2018-08-23

7.  The Impact of DNA Methylation in Hematopoietic Malignancies.

Authors:  Maria Guillamot; Luisa Cimmino; Iannis Aifantis
Journal:  Trends Cancer       Date:  2016-02-01

8.  Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors.

Authors:  Nicole M Anders; Jianyong Liu; Teresia Wanjiku; Hugh Giovinazzo; Jianya Zhou; Ajay Vaghasia; William G Nelson; Srinivasan Yegnasubramanian; Michelle A Rudek
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2016-03-21       Impact factor: 3.205

Review 9.  Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies.

Authors:  Vigneshwaran Venkatesan; Saranya Srinivasan; Prathibha Babu; Saravanabhavan Thangavel
Journal:  Mol Cell Biol       Date:  2020-12-21       Impact factor: 4.272

10.  Acute Hepatotoxicity After High-Dose Cytarabine for the Treatment of Relapsed Acute Myeloid Leukemia: A Case Report.

Authors:  Samuel H Fu; Alexander H Flannery; Melissa L Thompson Bastin
Journal:  Hosp Pharm       Date:  2018-06-01
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