Literature DB >> 23664359

Sphingosine kinase: a closer look at last.

Santiago Lima1, Sarah Spiegel.   

Abstract

Sphingosine-1-phosphate is a potent sphingolipid mediator, and the kinase that produces it, sphingosine kinase 1 (SphK1), has been implicated in cancer progression, inflammation, and cardiovascular diseases. In this issue of Structure, Wang and colleagues provide the scientific community with the long awaited structure of SphK1.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2013        PMID： 23664359      PMCID： PMC3711075          DOI： 10.1016/j.str.2013.04.006

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  11 in total

Review 1.  Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases.

Authors:  Gilles Labesse; Dominique Douguet; Liliane Assairi; Anne Marie Gilles
Journal:  Trends Biochem Sci       Date:  2002-06       Impact factor: 13.807

Review 2.  Sphingosine-1-phosphate signaling and its role in disease.

Authors:  Michael Maceyka; Kuzhuvelil B Harikumar; Sheldon Milstien; Sarah Spiegel
Journal:  Trends Cell Biol       Date:  2011-10-14       Impact factor: 20.808

Review 3.  Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors.

Authors:  K Alexa Orr Gandy; Lina M Obeid
Journal:  Biochim Biophys Acta       Date:  2012-07-16

4.  Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.

Authors:  Mark E Schnute; Matthew D McReynolds; Tom Kasten; Matthew Yates; Gina Jerome; John W Rains; Troii Hall; Jill Chrencik; Michelle Kraus; Ciaran N Cronin; Matthew Saabye; Maureen K Highkin; Richard Broadus; Shinji Ogawa; Kristin Cukyne; Laura E Zawadzke; Vincent Peterkin; Kaliapan Iyanar; Jeffrey A Scholten; Jay Wendling; Hideji Fujiwara; Olga Nemirovskiy; Arthur J Wittwer; Marek M Nagiec
Journal:  Biochem J       Date:  2012-05-15       Impact factor: 3.857

5.  FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells.

Authors:  Keng G Lim; Francesca Tonelli; Zaiguo Li; Xuequan Lu; Robert Bittman; Susan Pyne; Nigel J Pyne
Journal:  J Biol Chem       Date:  2011-04-04       Impact factor: 5.157

6.  Molecular cloning and functional characterization of murine sphingosine kinase.

Authors:  T Kohama; A Olivera; L Edsall; M M Nagiec; R Dickson; S Spiegel
Journal:  J Biol Chem       Date:  1998-09-11       Impact factor: 5.157

7.  Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition.

Authors:  Jeremy A Hengst; Jacquelyn M Guilford; Todd E Fox; Xujun Wang; Elizabeth J Conroy; Jong K Yun
Journal:  Arch Biochem Biophys       Date:  2009-09-24       Impact factor: 4.013

8.  Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.

Authors:  Zhulun Wang; Xiaoshan Min; Shou-Hua Xiao; Sheree Johnstone; William Romanow; David Meininger; Haoda Xu; Jinsong Liu; Jessica Dai; Songzhu An; Stephen Thibault; Nigel Walker
Journal:  Structure       Date:  2013-04-18       Impact factor: 5.006

9.  Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases.

Authors:  Darcie J Miller; Agoston Jerga; Charles O Rock; Stephen W White
Journal:  Structure       Date:  2008-07       Impact factor: 5.006

10.  A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.

Authors:  Steven W Paugh; Barbara S Paugh; Mohamed Rahmani; Dmitri Kapitonov; Jorge A Almenara; Tomasz Kordula; Sheldon Milstien; Jeffrey K Adams; Robert E Zipkin; Steven Grant; Sarah Spiegel
Journal:  Blood       Date:  2008-05-29       Impact factor: 22.113
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  4 in total

Review 1.  Sphingolipids and mitochondrial apoptosis.

Authors:  Gauri A Patwardhan; Levi J Beverly; Leah J Siskind
Journal:  J Bioenerg Biomembr       Date:  2016-04       Impact factor: 2.945

2.  A real-time high-throughput fluorescence assay for sphingosine kinases.

Authors:  Santiago Lima; Sheldon Milstien; Sarah Spiegel
Journal:  J Lipid Res       Date:  2014-05-02       Impact factor: 5.922

3.  Theoretical models to predict the inhibitory effect of ligands of sphingosine kinase 1 using QTAIM calculations and hydrogen bond dynamic propensity analysis.

Authors:  Marcela Vettorazzi; Cintia Menéndez; Lucas Gutiérrez; Sebastián Andujar; Gustavo Appignanesi; Ricardo D Enriz
Journal:  J Comput Aided Mol Des       Date:  2018-07-03       Impact factor: 3.686

4.  Human T-Cell Development and Thymic Egress: An Infectious Disease Perspective.

Authors:  Rachel S Resop; Christel H Uittenbogaart
Journal:  For Immunopathol Dis Therap       Date:  2015
  4 in total

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