| Literature DB >> 23663735 |
Abstract
Whether the red wine component resveratrol directly activates the NAD(+)-dependent protein deacetylase SIRT1 has been debated. A recent study by Hubbard et al. (2013) strengthens the case that SIRT1-activating compounds (STACs) function as positive allosteric regulators of SIRT1 and thereby regulate mitochondrial function.Entities:
Year: 2013 PMID： 23663735 DOI： 10.1016/j.cmet.2013.04.016
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287