Literature DB >> 23657200

Mobile phone use and risk of brain neoplasms and other cancers: prospective study.

Victoria S Benson1, Kirstin Pirie, Joachim Schüz, Gillian K Reeves, Valerie Beral, Jane Green.   

Abstract

BACKGROUND: Results from some retrospective studies suggest a possible increased risk of glioma and acoustic neuroma in users of mobile phones.
METHODS: The relation between mobile phone use and incidence of intracranial central nervous system (CNS) tumours and other cancers was examined in 791,710 middle-aged women in a UK prospective cohort, the Million Women Study. Cox regression models were used to estimate adjusted relative risks (RRs) and 95% confidence intervals (CIs). Women reported mobile phone use in 1999 to 2005 and again in 2009.
RESULTS: During 7 years' follow-up, 51,680 incident invasive cancers and 1,261 incident intracranial CNS tumours occurred. Risk among ever vs never users of mobile phones was not increased for all intracranial CNS tumours (RR = 1.01, 95% CI = 0.90-1.14, P = 0.82), for specified CNS tumour types nor for cancer at 18 other specified sites. For long-term users compared with never users, there was no appreciable association for glioma (10+ years: RR = 0.78, 95% CI = 0.55-1.10, P = 0.16) or meningioma (10+ years: RR = 1.10, 95% CI = 0.66-1.84, P = 0.71). For acoustic neuroma, there was an increase in risk with long term use vs never use (10+ years: RR = 2.46, 95% CI = 1.07-5.64, P = 0.03), the risk increasing with duration of use (trend among users, P = 0.03).
CONCLUSIONS: In this large prospective study, mobile phone use was not associated with increased incidence of glioma, meningioma or non-CNS cancers.

Entities:  

Keywords:  Acoustic neuroma; cellular phone; glioma; meningioma; neoplasms; prospective studies

Mesh:

Year:  2013        PMID: 23657200     DOI: 10.1093/ije/dyt072

Source DB:  PubMed          Journal:  Int J Epidemiol        ISSN: 0300-5771            Impact factor:   7.196


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