Literature DB >> 2365064

Identical genes for trimethoprim-resistant dihydrofolate reductase from Staphylococcus aureus in Australia and central Europe.

A Burdeska1, M Ott, W Bannwarth, R L Then.   

Abstract

The nucleotide sequence of a 1.25 kb BglII/EcoRI fragment from the 34 kb trimethoprim (Tp)-resistant plasmid pABU1 of Staphylococcus aureus 157/4696, isolated in Zürich, was determined. It contained the entire Tp-resistant dihydrofolate reductase gene, 197 bp of the thymidylate synthetase, 395 bp of a truncated gene and 111 bp of IS257R1. With the exception of one single base pair at position of 862 the sequence of the whole fragment was identical to nucleotides 1633 to 2885 of the Tp-resistant transposon Tn4003 in plasmid pSK1 from an Australian S. aureus isolate. This suggests the worldwide dissemination of Tn4003 in multiresistant Staphylococci.

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Year:  1990        PMID： 2365064     DOI： 10.1016/0014-5793(90)81529-w

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  12 in total

1.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-03-25       Impact factor: 16.971

2.  Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae.

Authors:  P V Adrian; K P Klugman
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

3.  Possible role of insertion sequence IS257 in dissemination and expression of high- and low-level trimethoprim resistance in staphylococci.

Authors:  A Leelaporn; N Firth; M E Byrne; E Roper; R A Skurray
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

4.  Correlation of trimethoprim and brodimoprim physicochemical and lipid membrane interaction properties with their accumulation in human neutrophils.

Authors:  M Fresta; P M Furneri; E Mezzasalma; V M Nicolosi; G Puglisi
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

5.  Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.

Authors:  Catherine Clark; Lois M Ednie; Gengrong Lin; Kathy Smith; Klaudia Kosowska-Shick; Pamela McGhee; Bonifacio Dewasse; Linda Beachel; Patrick Caspers; Bérangère Gaucher; Gürkan Mert; Stuart Shapiro; Peter C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

6.  Sequence identity with type VIII and association with IS176 of type IIIc dihydrofolate reductase from Shigella sonnei.

Authors:  N L Barg; S Register; C Thomson; S Amyes
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

7.  Characterization of the gene for chromosomal trimethoprim-sensitive dihydrofolate reductase of Staphylococcus aureus ATCC 25923.

Authors:  G E Dale; R L Then; D Stüber
Journal:  Antimicrob Agents Chemother       Date:  1993-07       Impact factor: 5.191

8.  Characterization of the gene for the chromosomal dihydrofolate reductase (DHFR) of Staphylococcus epidermidis ATCC 14990: the origin of the trimethoprim-resistant S1 DHFR from Staphylococcus aureus?

Authors:  G E Dale; C Broger; P G Hartman; H Langen; M G Page; R L Then; D Stüber
Journal:  J Bacteriol       Date:  1995-06       Impact factor: 3.490

9.  Cloning and characterization of a novel, plasmid-encoded trimethoprim-resistant dihydrofolate reductase from Staphylococcus haemolyticus MUR313.

Authors:  G E Dale; H Langen; M G Page; R L Then; D Stüber
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

10.  The antibacterial activities of aditoprim and its efficacy in the treatment of swine streptococcosis.

Authors:  Guyue Cheng; Yamei Xu; Xudong Zhu; Shuyu Xie; Liye Wang; Lingli Huang; Haihong Hao; Zhenli Liu; Yuanhu Pan; Dongmei Chen; Yulian Wang; Zonghui Yuan
Journal:  Sci Rep       Date:  2017-02-01       Impact factor: 4.379
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