Literature DB >> 23650244

The genomic psychiatry cohort: partners in discovery.

Michele T Pato1, Janet L Sobell, Helena Medeiros, Colony Abbott, Brooke M Sklar, Peter F Buckley, Evelyn J Bromet, Michael A Escamilla, Ayman H Fanous, Douglas S Lehrer, Fabio Macciardi, Dolores Malaspina, Steve A McCarroll, Stephen R Marder, Jennifer Moran, Christopher P Morley, Humberto Nicolini, Diana O Perkins, Shaun M Purcell, Mark H Rapaport, Pamela Sklar, Jordan W Smoller, James A Knowles, Carlos N Pato.   

Abstract

The Genomic Psychiatry Cohort (GPC) is a longitudinal resource designed to provide the necessary population-based sample for large-scale genomic studies, studies focusing on Research Domain Criteria (RDoC) and/or other alternate phenotype constructs, clinical and interventional studies, nested case-control studies, long-term disease course studies, and genomic variant-to-phenotype studies. We provide and will continue to encourage access to the GPC as an international resource. DNA and other biological samples and diagnostic data are available through the National Institute of Mental Health (NIMH) Repository. After appropriate review and approval by an advisory board, investigators are able to collaborate in, propose, and co-lead studies involving cohort participants.
Copyright © 2013 Wiley Periodicals, Inc.

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Year:  2013        PMID: 23650244      PMCID: PMC3729260          DOI: 10.1002/ajmg.b.32160

Source DB:  PubMed          Journal:  Am J Med Genet B Neuropsychiatr Genet        ISSN: 1552-4841            Impact factor:   3.568


  32 in total

1.  Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia.

Authors:  Jingchun Chen; Grace Lee; Ayman H Fanous; Zhongming Zhao; Peilin Jia; Anthony O'Neill; Dermot Walsh; Kenneth S Kendler; Xiangning Chen
Journal:  Schizophr Res       Date:  2011-07-14       Impact factor: 4.939

2.  Don't give up on GWAS.

Authors:  P Sullivan
Journal:  Mol Psychiatry       Date:  2011-08-09       Impact factor: 15.992

3.  Genetic classification of populations using supervised learning.

Authors:  Michael Bridges; Elizabeth A Heron; Colm O'Dushlaine; Ricardo Segurado; Derek Morris; Aiden Corvin; Michael Gill; Carlos Pinto
Journal:  PLoS One       Date:  2011-05-12       Impact factor: 3.240

4.  A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia.

Authors:  Peilin Jia; Lily Wang; Ayman H Fanous; Xiangning Chen; Kenneth S Kendler; Zhongming Zhao
Journal:  J Med Genet       Date:  2011-12-20       Impact factor: 6.318

5.  GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.

Authors:  X Chen; G Lee; B S Maher; A H Fanous; J Chen; Z Zhao; A Guo; E van den Oord; P F Sullivan; J Shi; D F Levinson; P V Gejman; A Sanders; J Duan; M J Owen; N J Craddock; M C O'Donovan; J Blackman; D Lewis; G K Kirov; W Qin; S Schwab; D Wildenauer; K Chowdari; V Nimgaonkar; R E Straub; D R Weinberger; F A O'Neill; D Walsh; M Bronstein; A Darvasi; T Lencz; A K Malhotra; D Rujescu; I Giegling; T Werge; T Hansen; A Ingason; M M Nöethen; M Rietschel; S Cichon; S Djurovic; O A Andreassen; R M Cantor; R Ophoff; A Corvin; D W Morris; M Gill; C N Pato; M T Pato; A Macedo; H M D Gurling; A McQuillin; J Pimm; C Hultman; P Lichtenstein; P Sklar; S M Purcell; E Scolnick; D St Clair; D H R Blackwood; K S Kendler
Journal:  Mol Psychiatry       Date:  2010-09-14       Impact factor: 15.992

6.  Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility.

Authors:  C O'Dushlaine; E Kenny; E Heron; G Donohoe; M Gill; D Morris; A Corvin
Journal:  Mol Psychiatry       Date:  2010-02-16       Impact factor: 15.992

7.  Replicated genetic evidence supports a role for HOMER2 in schizophrenia.

Authors:  William P Gilks; Emma H Allott; Gary Donohoe; Elizabeth Cummings; Michael Gill; Aiden P Corvin; Derek W Morris
Journal:  Neurosci Lett       Date:  2009-11-13       Impact factor: 3.046

8.  Genome-wide association study identifies five new schizophrenia loci.

Authors: 
Journal:  Nat Genet       Date:  2011-09-18       Impact factor: 38.330

9.  Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.

Authors:  Soumya Raychaudhuri; Joshua M Korn; Steven A McCarroll; David Altshuler; Pamela Sklar; Shaun Purcell; Mark J Daly
Journal:  PLoS Genet       Date:  2010-09-09       Impact factor: 5.917

10.  Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

Authors:  Shaun M Purcell; Naomi R Wray; Jennifer L Stone; Peter M Visscher; Michael C O'Donovan; Patrick F Sullivan; Pamela Sklar
Journal:  Nature       Date:  2009-07-01       Impact factor: 49.962

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  30 in total

Review 1.  International Society of Psychiatric Genetics Ethics Committee: Issues facing us.

Authors:  Gabriel Lázaro-Muñoz; Maya Sabatello; Laura Huckins; Holly Peay; Franziska Degenhardt; Bettina Meiser; Todd Lencz; Takahiro Soda; Anna Docherty; David Crepaz-Keay; Jehannine Austin; Roseann E Peterson; Lea K Davis
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2019-05-23       Impact factor: 3.568

2.  Apolipoprotein E-ε4 allele predicts escalation of psychotic symptoms in late adulthood.

Authors:  Katherine Jonas; Sean Clouston; Kaiqiao Li; Laura J Fochtmann; Todd Lencz; Anil K Malhotra; David Cicero; Greg Perlman; Evelyn J Bromet; Roman Kotov
Journal:  Schizophr Res       Date:  2018-12-21       Impact factor: 4.939

3.  Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type.

Authors:  Elena Estrada; Sarah M Hartz; Jeffrey Tran; Donald M Hilty; Pamela Sklar; Jordan W Smoller; Michele T Pato; Carlos N Pato
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2015-10-15       Impact factor: 3.568

4.  Challenges and Opportunities to Meet the Mental Health Needs of Underserved and Disenfranchised Populations in the United States.

Authors:  Francesca Mongelli; Penelope Georgakopoulos; Michele T Pato
Journal:  Focus (Am Psychiatr Publ)       Date:  2020-01-24

5.  Comorbidity of severe psychotic disorders with measures of substance use.

Authors:  Sarah M Hartz; Carlos N Pato; Helena Medeiros; Patricia Cavazos-Rehg; Janet L Sobell; James A Knowles; Laura J Bierut; Michele T Pato
Journal:  JAMA Psychiatry       Date:  2014-03       Impact factor: 21.596

6.  A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.

Authors:  Jubao Duan; Jianxin Shi; Alessia Fiorentino; Catherine Leites; Xiangning Chen; Winton Moy; Jingchun Chen; Boian S Alexandrov; Anny Usheva; Deli He; Jessica Freda; Niamh L O'Brien; Andrew McQuillin; Alan R Sanders; Elliot S Gershon; Lynn E DeLisi; Alan R Bishop; Hugh M D Gurling; Michele T Pato; Douglas F Levinson; Kenneth S Kendler; Carlos N Pato; Pablo V Gejman
Journal:  Am J Hum Genet       Date:  2014-11-26       Impact factor: 11.025

7.  Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.

Authors:  Alden Y Huang; Dongmei Yu; Lea K Davis; Jae Hoon Sul; Fotis Tsetsos; Vasily Ramensky; Ivette Zelaya; Eliana Marisa Ramos; Lisa Osiecki; Jason A Chen; Lauren M McGrath; Cornelia Illmann; Paul Sandor; Cathy L Barr; Marco Grados; Harvey S Singer; Markus M Nöthen; Johannes Hebebrand; Robert A King; Yves Dion; Guy Rouleau; Cathy L Budman; Christel Depienne; Yulia Worbe; Andreas Hartmann; Kirsten R Müller-Vahl; Manfred Stuhrmann; Harald Aschauer; Mara Stamenkovic; Monika Schloegelhofer; Anastasios Konstantinidis; Gholson J Lyon; William M McMahon; Csaba Barta; Zsanett Tarnok; Peter Nagy; James R Batterson; Renata Rizzo; Danielle C Cath; Tomasz Wolanczyk; Cheston Berlin; Irene A Malaty; Michael S Okun; Douglas W Woods; Elliott Rees; Carlos N Pato; Michele T Pato; James A Knowles; Danielle Posthuma; David L Pauls; Nancy J Cox; Benjamin M Neale; Nelson B Freimer; Peristera Paschou; Carol A Mathews; Jeremiah M Scharf; Giovanni Coppola
Journal:  Neuron       Date:  2017-06-21       Impact factor: 17.173

Review 8.  An autism case history to review the systematic analysis of large-scale data to refine the diagnosis and treatment of neuropsychiatric disorders.

Authors:  Isaac S Kohane
Journal:  Biol Psychiatry       Date:  2014-06-12       Impact factor: 13.382

9.  Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis.

Authors: 
Journal:  Mol Psychiatry       Date:  2017-08-01       Impact factor: 15.992

10.  Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.

Authors:  Carolina Montano; Margaret A Taub; Andrew Jaffe; Eirikur Briem; Jason I Feinberg; Rakel Trygvadottir; Adrian Idrizi; Arni Runarsson; Birna Berndsen; Ruben C Gur; Tyler M Moore; Rodney T Perry; Doug Fugman; Sarven Sabunciyan; Robert H Yolken; Thomas M Hyde; Joel E Kleinman; Janet L Sobell; Carlos N Pato; Michele T Pato; Rodney C Go; Vishwajit Nimgaonkar; Daniel R Weinberger; David Braff; Raquel E Gur; Margaret Daniele Fallin; Andrew P Feinberg
Journal:  JAMA Psychiatry       Date:  2016-05-01       Impact factor: 21.596

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