Literature DB >> 23645994

Nanocrystals for the parenteral delivery of poorly water-soluble drugs.

Bo Sun1, Yoon Yeo.   

Abstract

Nanocrystals have drawn increasing interest in pharmaceutical industry because of the ability to improve dissolution of poorly water-soluble drugs. Nanocrystals can be produced by top-down and bottom-up technologies and have been explored for a variety of therapeutic applications. Here we review the methods of nanocrystal production and parenteral applications of nanocrystals. We also discuss remaining challenges in the development of nanocrystal products.

Entities:  

Keywords:  Nanocrystals; nanosuspension; parenteral applications; poorly water-soluble drugs

Year:  2012        PMID： 23645994      PMCID： PMC3640575          DOI： 10.1016/j.cossms.2012.10.004

Source DB:  PubMed          Journal:  Curr Opin Solid State Mater Sci        ISSN： 1359-0286            Impact factor:   11.354


  95 in total

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3.  Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors.

Authors:  Hany S M Ali; Peter York; Nicholas Blagden
Journal:  Int J Pharm       Date:  2009-04-05       Impact factor: 5.875

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5.  Ocular tolerability of Eudragit RS100 and RL100 nanosuspensions as carriers for ophthalmic controlled drug delivery.

Authors:  R Pignatello; C Bucolo; G Puglisi
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Authors:  Gaurav Bajaj; Yoon Yeo
Journal:  Pharm Res       Date:  2010-03-03       Impact factor: 4.200

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Authors:  M Kakran; N G Sahoo; L Li; Z Judeh; Y Wang; K Chong; L Loh
Journal:  Int J Pharm       Date:  2009-09-23       Impact factor: 5.875

8.  Crystallization of hydrocortisone acetate: influence of polymers.

Authors:  S L Raghavan; A Trividic; A F Davis; J Hadgraft
Journal:  Int J Pharm       Date:  2001-01-16       Impact factor: 5.875

9.  Production and characterization of Hesperetin nanosuspensions for dermal delivery.

Authors:  Prabhat R Mishra; Loaye Al Shaal; Rainer H Müller; Cornelia M Keck
Journal:  Int J Pharm       Date:  2008-12-31       Impact factor: 5.875

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  25 in total

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7.  Enhanced Intramuscular Bioavailability of Cannabidiol Using Nanocrystals: Formulation, In Vitro Appraisal, and Pharmacokinetics.

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Review 8.  Recent advances in protein and Peptide drug delivery: a special emphasis on polymeric nanoparticles.

Authors:  Ashaben Patel; Mitesh Patel; Xiaoyan Yang; Ashim K Mitra
Journal:  Protein Pept Lett       Date:  2014       Impact factor: 1.890

9.  Enhancing Docetaxel Delivery to Multidrug-Resistant Cancer Cells with Albumin-Coated Nanocrystals.

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10.  Cryochemical Production of Drug Nanoforms: Particle Size and Crystal Phase Control of the Antibacterial Medication 2,3-Quinoxalinedimethanol-1,4-dioxide (Dioxidine).

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