Literature DB >> 23638413

CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy.

Zhi-Jia Fang1, Jenny Y Zhang, Wei-Min He.   

Abstract

AIM: : To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO).
METHODS: A total of 605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orbital CT imaging. The increased orbital volume features, such as changes from extraocular muscles, orbital fat, or both, were analyzed.
RESULTS: A total of 605 eyes were analyzed, among them 62.98% presented grade I exophthalmos, while 36.02% showed grade II exophthalmos. In grade I, 56.69% showed orbital fat change, and in grade II, 89.29% exhibited extraocular muscle enlargement.
CONCLUSION: Orbital fat and extraocular muscle enlargement are likely to be observed on CTs of subjects with mild and severe exophthalmos, respectively. Our results suggest that CT findings may guide TAO clinical therapy recommendations and prognosis.

Entities:  

Keywords:  computed tomography (CT); exophthalmos; thyroid-associated ophthalmopathy (TAO)

Year:  2013        PMID: 23638413      PMCID: PMC3633750          DOI: 10.3980/j.issn.2222-3959.2013.02.07

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  18 in total

1.  Normative measurements of orbital structures using MRI.

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Journal:  J Comput Assist Tomogr       Date:  2000 May-Jun       Impact factor: 1.826

2.  Significance of orbital fatty tissue for exophthalmos in thyroid-associated ophthalmopathy.

Authors:  Yasuhiro Nishida; Suna Tian; Bengt Isberg; Osamu Hayashi; Leif Tallstedt; Gunnar Lennerstrand
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2002-06-20       Impact factor: 3.117

3.  Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.

Authors:  Terry J Smith; Neil Hoa
Journal:  J Clin Endocrinol Metab       Date:  2004-10       Impact factor: 5.958

4.  Evaluation of rectus extraocular muscles using dynamic contrast-enhanced MR imaging in patients with Graves' ophthalmopathy for assessment of disease activity.

Authors:  Hong Jiang; Zhenchang Wang; Junfang Xian; Jing Li; Qinghua Chen; Likun Ai
Journal:  Acta Radiol       Date:  2011-12-07       Impact factor: 1.990

5.  Orbital magnetic resonance imaging combined with clinical activity score can improve the sensitivity of detection of disease activity and prediction of response to immunosuppressive therapy for Graves' ophthalmopathy.

Authors:  Seigo Tachibana; Tsukasa Murakami; Hitoshi Noguchi; Yasushi Noguchi; Akiko Nakashima; Yufuko Ohyabu; Shiro Noguchi
Journal:  Endocr J       Date:  2010-08-19       Impact factor: 2.349

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Journal:  Swiss Med Wkly       Date:  2009-10-31       Impact factor: 2.193

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Journal:  Br Med J       Date:  1977-01-29

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Journal:  J Clin Endocrinol Metab       Date:  1990-01       Impact factor: 5.958

Review 10.  Diagnostic criteria for Graves' ophthalmopathy.

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Journal:  Am J Ophthalmol       Date:  1995-06       Impact factor: 5.258

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  9 in total

1.  Fractional anisotropy and diffusivity changes in thyroid-associated orbitopathy.

Authors:  Ji Sung Han; Hyung Suk Seo; Young Hen Lee; Hwa Lee; Sang-Il Suh; Eun-Kee Jeong; Nabraj Sapkota; Ki Joon Kim
Journal:  Neuroradiology       Date:  2016-11-14       Impact factor: 2.804

2.  Corneal biomechanical changes and intraocular pressure in patients with thyroid orbitopathy.

Authors:  Zofia Pniakowska; Anna Klysik; Roman Gos; Piotr Jurowski
Journal:  Int J Ophthalmol       Date:  2016-03-18       Impact factor: 1.779

3.  Cross-sectional computed tomography assessment of exophthalmos in comparison to clinical measurement via Hertel exophthalmometry.

Authors:  A Klingenstein; C Samel; A Garip-Kübler; C Hintschich; U G Müller-Lisse
Journal:  Sci Rep       Date:  2022-07-13       Impact factor: 4.996

4.  Orbital Fat Volumetry and Water Fraction Measurements Using T2-Weighted FSE-IDEAL Imaging in Patients with Thyroid-Associated Orbitopathy.

Authors:  Y Kaichi; K Tanitame; H Itakura; H Ohno; M Yoneda; Y Takahashi; Y Akiyama; K Awai
Journal:  AJNR Am J Neuroradiol       Date:  2016-06-30       Impact factor: 3.825

5.  Thyroid-associated Orbitopathy: Quantitative Evaluation of the Orbital Fat Volume and Edema Using IDEAL-FSE.

Authors:  Yoko Kaichi; Keizo Tanitame; Hiroaki Terada; Hideki Itakura; Haruya Ohno; Masayasu Yoneda; Yuji Takahashi; Yuji Akiyama; Kazuo Awai
Journal:  Eur J Radiol Open       Date:  2019-05-18

6.  Hertel exophthalmometer versus computed tomography scan in proptosis estimation in thyroid-associated orbitopathy.

Authors:  Na Ri Park; Jun Hyung Moon; Jeong Kyu Lee
Journal:  Clin Ophthalmol       Date:  2019-08-02

7.  Preliminary study of abnormalities in saccade dynamics in patients with hyperthyroidism with no pre-existing eye damage.

Authors:  Yan Sun; Xinhui Xie; Yongxia Xu; Chen Wang; Xiaoming Kong
Journal:  Exp Ther Med       Date:  2020-01-17       Impact factor: 2.447

8.  Orbital Volumetry in Graves' Orbitopathy: Muscle and Fat Involvement in relation to Dysthyroid Optic Neuropathy.

Authors:  Moug Al-Bakri; Ase Krogh Rasmussen; Carsten Thomsen; Peter Bjerre Toft
Journal:  ISRN Ophthalmol       Date:  2014-04-02

Review 9.  Application of lateral tarsoconjunctival flap to correct ocular complications of Madelung's disease: A case report and literature review.

Authors:  Lung-Chi Lee; Tsu-Heng Weng; Ke-Hao Huang; Hsin-Ting Lin; Chang-Min Liang; Ming-Cheng Tai; Jiann-Torng Chen; Ke-Hung Chien
Journal:  Medicine (Baltimore)       Date:  2018-10       Impact factor: 1.817

  9 in total

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