Literature DB >> 2363514

High-speed separations of DNA sequencing reactions by capillary electrophoresis.

H Drossman1, J A Luckey, A J Kostichka, J D'Cunha, L M Smith.   

Abstract

Fluorescently labeled DNA fragments generated in enzymatic sequencing reactions are rapidly separated by capillary gel electrophoresis and detected at attomole levels within the gel-filled capillary. The application of this technology to automated DNA sequence analysis may permit the development of a second generation automated sequencer capable of efficient and cost-effective sequence analysis on the genomic scale.

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Year:  1990        PMID： 2363514     DOI： 10.1021/ac00208a003

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  14 in total

1.  Electrokinetic stretching of tethered DNA.

Authors:  Sean Ferree; Harvey W Blanch
Journal:  Biophys J       Date:  2003-10       Impact factor: 4.033

2.  Multiwavelength fluorescence detection for DNA sequencing using capillary electrophoresis.

Authors:  A E Karger; J M Harris; R F Gesteland
Journal:  Nucleic Acids Res       Date:  1991-09-25       Impact factor: 16.971

3.  Rapid DNA sequencing by horizontal ultrathin gel electrophoresis.

Authors:  R L Brumley; L M Smith
Journal:  Nucleic Acids Res       Date:  1991-08-11       Impact factor: 16.971

4.  Separation of selected PAHs by using high performance capillary electrophoresis with modifiers.

Authors:  Y F Yik; C P Ong; S B Khoo; H K Lee; S F Li
Journal:  Environ Monit Assess       Date:  1991-10       Impact factor: 2.513

5.  High speed DNA sequencing by capillary electrophoresis.

Authors:  J A Luckey; H Drossman; A J Kostichka; D A Mead; J D'Cunha; T B Norris; L M Smith
Journal:  Nucleic Acids Res       Date:  1990-08-11       Impact factor: 16.971

6.  High-throughput genetic analysis using microfabricated 96-sample capillary array electrophoresis microplates.

Authors:  P C Simpson; D Roach; A T Woolley; T Thorsen; R Johnston; G F Sensabaugh; R A Mathies
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

7.  Simple miniaturized gel system for DNA sequence analysis.

Authors:  A Stein; S A Hill; Z Cheng; M Bina
Journal:  Nucleic Acids Res       Date:  1998-01-15       Impact factor: 16.971

Review 8.  Applications of capillary electrophoresis in pharmaceutical analysis.

Authors:  S R Rabel; J F Stobaugh
Journal:  Pharm Res       Date:  1993-02       Impact factor: 4.200

Review 9.  DNA sequencing by CE.

Authors:  Barry L Karger; András Guttman
Journal:  Electrophoresis       Date:  2009-06       Impact factor: 3.535

10.  Two-label peak-height encoded DNA sequencing by capillary gel electrophoresis: three examples.

Authors:  D Chen; H R Harke; N J Dovichi
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971
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