BACKGROUND AND OBJECTIVES: The Spanish National Cutaneous Melanoma Registry (Registro Nacional de Melanoma Cutáneo [RNMC]) was created in 1997 to record the characteristics of melanoma at diagnosis. In this article, we describe the characteristics of these tumors at diagnosis. PATIENTS AND METHODS: This was a cross-sectional observational study of prevalent and incident cases of melanoma for which initial biopsy results were available in the population-based RNMC. RESULTS: The RNMC contains information on 14,039 patients. We analyzed the characteristics of 13,628 melanomas diagnosed between 1997 and 2011. In total, 56.5% of the patients studied were women and 43.5% were men. The mean age of the group was 57 years (95% CI, 56.4-57 years) while median age was 58 years. The most common tumor site was the trunk (37.1%), followed by the lower limbs (27.3%). The most frequent clinical-pathologic subtype was superficial spreading melanoma (n=7481, 62.6%), followed by nodular melanoma (n=2014, 16.8%). Localized disease was observed in 86.2% of cases (n=10,382), regional metastasis in 9.9% (n=1188), and distant metastasis in 3.9% (n=479). Independently of age at diagnosis, men had thicker tumors, more ulceration, higher lactate dehydrogenase levels, and a higher rate of metastasis than women (P<.001). CONCLUSIONS: Based on our findings, melanoma prevention campaigns should primarily target men over 50 years old because they tend to develop thicker tumors and therefore have a worse prognosis.
BACKGROUND AND OBJECTIVES: The Spanish National Cutaneous Melanoma Registry (Registro Nacional de Melanoma Cutáneo [RNMC]) was created in 1997 to record the characteristics of melanoma at diagnosis. In this article, we describe the characteristics of these tumors at diagnosis. PATIENTS AND METHODS: This was a cross-sectional observational study of prevalent and incident cases of melanoma for which initial biopsy results were available in the population-based RNMC. RESULTS: The RNMC contains information on 14,039 patients. We analyzed the characteristics of 13,628 melanomas diagnosed between 1997 and 2011. In total, 56.5% of the patients studied were women and 43.5% were men. The mean age of the group was 57 years (95% CI, 56.4-57 years) while median age was 58 years. The most common tumor site was the trunk (37.1%), followed by the lower limbs (27.3%). The most frequent clinical-pathologic subtype was superficial spreading melanoma (n=7481, 62.6%), followed by nodular melanoma (n=2014, 16.8%). Localized disease was observed in 86.2% of cases (n=10,382), regional metastasis in 9.9% (n=1188), and distant metastasis in 3.9% (n=479). Independently of age at diagnosis, men had thicker tumors, more ulceration, higher lactate dehydrogenase levels, and a higher rate of metastasis than women (P<.001). CONCLUSIONS: Based on our findings, melanoma prevention campaigns should primarily target men over 50 years old because they tend to develop thicker tumors and therefore have a worse prognosis.
Authors: A Tejera-Vaquerizo; J Cañueto; A Toll; J Santos-Juanes; A Jaka; C Ferrandiz; O Sanmartín; S Ribero; D Moreno-Ramírez; F Almazán; M J Fuente; S Podlipnik; E Nagore Journal: Actas Dermosifiliogr Date: 2020-09-20
Authors: I Márquez-Rodas; A Arance; A Berrocal; C L Larios; J Curto-García; I X Campos-Tapias; A B Blanca; S Martin-Algarra Journal: Clin Transl Oncol Date: 2019-08-21 Impact factor: 3.405
Authors: Antonio Tejera-Vaquerizo; Simone Ribero; Susana Puig; Aram Boada; Sabela Paradela; David Moreno-Ramírez; Javier Cañueto; Blanca de Unamuno; Ana Brinca; Miguel A Descalzo-Gallego; Simona Osella-Abate; Paola Cassoni; Cristina Carrera; Sergi Vidal-Sicart; Antoni Bennássar; Ramón Rull; Llucìa Alos; Celia Requena; Isidro Bolumar; Víctor Traves; Ángel Pla; A Fernández-Orland; Ane Jaka; María T Fernández-Figueres; Josep M Hilari; Pol Giménez-Xavier; Ricardo Vieira; Rafael Botella-Estrada; Concepción Román-Curto; Lara Ferrándiz; Nicolás Iglesias-Pena; Carlos Ferrándiz; Josep Malvehy; Pietro Quaglino; Eduardo Nagore Journal: Cancer Med Date: 2019-06-18 Impact factor: 4.452
Authors: A Tejera-Vaquerizo; M T Fernández-Figueras; A Santos-Briz; J J Ríos-Martín; C Monteagudo; A Fernández-Flores; C Requena; V Traves; M A Descalzo-Gallego; J L Rodríguez-Peralto Journal: Actas Dermosifiliogr (Engl Ed) Date: 2020-10-07
Authors: Nieves Martínez-Campayo; Sabela Paradela de la Morena; Sonia Pértega-Díaz; Luisa Iglesias Pena; Pia Vihinen; Kalle Mattila; Marko B Lens; Antonio Tejera-Vaquerizo; Eduardo Fonseca Journal: J Clin Med Date: 2021-12-24 Impact factor: 4.241
Authors: A Tejera-Vaquerizo; J Cañueto; A Toll; J Santos-Juanes; A Jaka; C Ferrandiz-Pulido; O Sanmartín; S Ribero; D Moreno-Ramírez; F Almazán; M J Fuente; S Podlipnik; E Nagore Journal: Actas Dermosifiliogr (Engl Ed) Date: 2020-05-11
Authors: S Podlipnik; C Carrera; A Boada; N A Richarz; J L López-Estebaranz; F Pinedo-Moraleda; M Elosua-González; M M Martín-González; R Carrillo-Gijón; P Redondo; E Moreno; J Malvehy; S Puig Journal: J Eur Acad Dermatol Venereol Date: 2019-02-28 Impact factor: 6.166