M V Forslund1, C Roe, S Sigurdardottir, N Andelic. 1. Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway.
Abstract
AIMS: To describe health-related quality of life (HRQL) 2 years after moderate-to-severe traumatic brain injury (TBI) and to assess predictors of HRQL. MATERIALS AND METHODS: A prospective cohort study of 91 patients, aged 16-55 years, admitted with moderate-to-severe TBI to a trauma referral centre between 2005 and 2007, with follow-up at 1 and 2 years. Mean age was 31.1 (SD = 11.3) years, and 77% were men. Injury severity was evaluated by the Glasgow Coma Scale (GCS), head CT scan (using a modified Marshall Classification), Injury Severity Score (ISS) and post-traumatic amnesia (PTA). The Functional Independence Measure (FIM), Community Integration Questionnaire (CIQ), Beck Depression Inventory (BDI) and Medical Outcomes 36-item Short Form Health Survey (SF-36) were administered at follow-up visits. The main outcome measures were the Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36. RESULTS: HRQL appears to be relatively stable between 1 and 2 years after injury. In the multivariate linear regression, younger age (β = -0.20, P = 0.032), more severe TBI (β = 0.28, P = 0.016), more severe overall trauma (β = 0.22, P = 0.026), higher levels of community integration (β = 0.36, P = 0.019) and higher positive change in PCS scores from 1 to 2 years (β = 0.41, P < 0.001) predicted better self-reported physical health 2 years post-TBI. Lower scores for depression (β = -0.70, P < 0.001) and a higher positive change in MCS scores (β = 0.62, P < 0.001) predicted better self-reported mental health. CONCLUSIONS: Future interventions should focus on aspects related to HRQL that are more easily modified, such as physical functioning, home and social integration, productivity, and mental and emotional status.
AIMS: To describe health-related quality of life (HRQL) 2 years after moderate-to-severe traumatic brain injury (TBI) and to assess predictors of HRQL. MATERIALS AND METHODS: A prospective cohort study of 91 patients, aged 16-55 years, admitted with moderate-to-severe TBI to a trauma referral centre between 2005 and 2007, with follow-up at 1 and 2 years. Mean age was 31.1 (SD = 11.3) years, and 77% were men. Injury severity was evaluated by the Glasgow Coma Scale (GCS), head CT scan (using a modified Marshall Classification), Injury Severity Score (ISS) and post-traumatic amnesia (PTA). The Functional Independence Measure (FIM), Community Integration Questionnaire (CIQ), Beck Depression Inventory (BDI) and Medical Outcomes 36-item Short Form Health Survey (SF-36) were administered at follow-up visits. The main outcome measures were the Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36. RESULTS: HRQL appears to be relatively stable between 1 and 2 years after injury. In the multivariate linear regression, younger age (β = -0.20, P = 0.032), more severe TBI (β = 0.28, P = 0.016), more severe overall trauma (β = 0.22, P = 0.026), higher levels of community integration (β = 0.36, P = 0.019) and higher positive change in PCS scores from 1 to 2 years (β = 0.41, P < 0.001) predicted better self-reported physical health 2 years post-TBI. Lower scores for depression (β = -0.70, P < 0.001) and a higher positive change in MCS scores (β = 0.62, P < 0.001) predicted better self-reported mental health. CONCLUSIONS: Future interventions should focus on aspects related to HRQL that are more easily modified, such as physical functioning, home and social integration, productivity, and mental and emotional status.
Authors: Richard Rubenstein; Binggong Chang; John K Yue; Allen Chiu; Ethan A Winkler; Ava M Puccio; Ramon Diaz-Arrastia; Esther L Yuh; Pratik Mukherjee; Alex B Valadka; Wayne A Gordon; David O Okonkwo; Peter Davies; Sanjeev Agarwal; Fan Lin; George Sarkis; Hamad Yadikar; Zhihui Yang; Geoffrey T Manley; Kevin K W Wang; Shelly R Cooper; Kristen Dams-O'Connor; Allison J Borrasso; Tomoo Inoue; Andrew I R Maas; David K Menon; David M Schnyer; Mary J Vassar Journal: JAMA Neurol Date: 2017-09-01 Impact factor: 18.302
Authors: Alba Aza; Miguel Ángel Verdugo; María Begoña Orgaz; María Fernández; Antonio Manuel Amor Journal: Qual Life Res Date: 2019-12-18 Impact factor: 4.147
Authors: Nada Andelic; Paul B Perrin; Marit V Forslund; Helene L Soberg; Solrun Sigurdardottir; Unni Sveen; Tone Jerstad; Cecilie Roe Journal: J Neurol Date: 2014-12-05 Impact factor: 4.849
Authors: Helene Lundgaard Soberg; Cecilie Roe; Cathrine Brunborg; Nicole von Steinbüchel; Nada Andelic Journal: Health Qual Life Outcomes Date: 2017-01-19 Impact factor: 3.186
Authors: Kayla M Frodsham; Joseph E Fair; R Brock Frost; Ramona O Hopkins; Erin D Bigler; Sarah Majercik; Joseph Bledsoe; David Ryser; Joel MacDonald; Ryan Barrett; Susan D Horn; David Pisani; Mark Stevens; Michael J Larson Journal: Am J Phys Med Rehabil Date: 2020-09 Impact factor: 3.412