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Literature DB >> 23620845

RNAi: antiviral therapy against dengue virus.

Abstract

Dengue virus infection has become a global threat affecting around 100 countries in the world. Currently, there is no licensed antiviral agent available against dengue. Thus, there is a strong need to develop therapeutic strategies that can tackle this life threatening disease. RNA interference is an important and effective gene silencing process which degrades targeted RNA by a sequence specific process. Several studies have been conducted during the last decade to evaluate the efficiency of siRNA in inhibiting dengue virus replication. This review summarizes siRNAs as a therapeutic approach against dengue virus serotypes and concludes that siRNAs against virus and host genes can be next generation treatment of dengue virus infection.

Entities: Disease Species

Keywords: Dengue haemorrhagic fever; Dengue virus; RNA interference; Small interference RNA

Mesh：

Substances：
RNA, Small Interfering

Year: 2013 PMID： 23620845 PMCID： PMC3631757 DOI： 10.1016/S2221-1691(13)60057-X

Source DB: PubMed Journal: Asian Pac J Trop Biomed ISSN： 2221-1691

38 in total

Review 1. RNA-triggered gene silencing.

Authors: A Fire
Journal: Trends Genet Date: 1999-09 Impact factor: 11.639

2. Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.

Authors: Pradeep Devappa Uchil; Vijaya Satchidanandam
Journal: J Biol Chem Date: 2003-04-16 Impact factor: 5.157

Review 3. The role of RNA interference in heterochromatic silencing.

Authors: Zachary Lippman; Rob Martienssen
Journal: Nature Date: 2004-09-16 Impact factor: 49.962

Review 4. Dengue.

Authors: Scott B Halstead
Journal: Lancet Date: 2007-11-10 Impact factor: 79.321

5. Molecular dissection of the gibberellin/abscisic acid signaling pathways by transiently expressed RNA interference in barley aleurone cells.

Authors: Rodolfo Zentella; Daisuke Yamauchi; Tuan-hua David Ho
Journal: Plant Cell Date: 2002-09 Impact factor: 11.277

6. RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.

Authors: A M A Nasirudeen; Hui Hui Wong; Peiling Thien; Shengli Xu; Kong-Peng Lam; Ding Xiang Liu
Journal: PLoS Negl Trop Dis Date: 2011-01-04

7. Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan.

Authors: Zareen Fatima; Muhammad Idrees; Mohammad A Bajwa; Zarfishan Tahir; Obaid Ullah; Muhammad Q Zia; Abrar Hussain; Madiha Akram; Bushra Khubaib; Samia Afzal; Saira Munir; Sana Saleem; Bisma Rauff; Sadaf Badar; Mahrukh Naudhani; Sadia Butt; Mahwish Aftab; Liaqat Ali; Muhammad Ali
Journal: BMC Microbiol Date: 2011-09-10 Impact factor: 3.605

Review 8. Dengue virus.

Authors: Ted M Ross
Journal: Clin Lab Med Date: 2010-03 Impact factor: 1.935

9. Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery.

Authors: Weidong Zhang; Rajeswari Singam; Gary Hellermann; Xiaoyuan Kong; Homero San Juan; Richard F Lockey; Shuen-Ju Wu; Kevin Porter; Shyam S Mohapatra
Journal: Genet Vaccines Ther Date: 2004-08-09

Review 10. RNA interference against viruses: strike and counterstrike.

Authors: Joost Haasnoot; Ellen M Westerhout; Ben Berkhout
Journal: Nat Biotechnol Date: 2007-12 Impact factor: 54.908

16 in total

1. Multiple dengue virus serotypes resistant transgenic Aedes aegypti fitness evaluated under laboratory conditions.

Authors: Hewawasam Patuwatha Badathuruge Kalindu Dulanja Ramyasoma; Ranil Samantha Dassanayake; Menaka Hapugoda; Margareth L Capurro; Yasanthi Illika Nilmini Silva Gunawardene
Journal: RNA Biol Date: 2020-03-06 Impact factor: 4.652

2. Molecular Docking Based Screening of Plant Flavonoids as Dengue NS1 Inhibitors.

Authors: Muhammad Tahir Ul Qamar; Arooj Mumtaz; Rabbia Naseem; Amna Ali; Tabeer Fatima; Tehreem Jabbar; Zubair Ahmad; Usman Ali Ashfaq
Journal: Bioinformation Date: 2014-07-22

3. Delivery of antiviral small interfering RNA with gold nanoparticles inhibits dengue virus infection in vitro.

Authors: Amber M Paul; Yongliang Shi; Dhiraj Acharya; Jessica R Douglas; Amanda Cooley; John F Anderson; Faqing Huang; Fengwei Bai
Journal: J Gen Virol Date: 2014-05-14 Impact factor: 3.891

4. In Vitro Inhibitory Analysis of Rationally Designed siRNAs against MERS-CoV Replication in Huh7 Cells.

Authors: Sherif Aly El-Kafrawy; Sayed Sartaj Sohrab; Zeenat Mirza; Ahmed M Hassan; Fatima Alsaqaf; Esam Ibraheem Azhar
Journal: Molecules Date: 2021-04-29 Impact factor: 4.411

5. Development of global consensus sequence of HCV glycoproteins involved in viral entry.

Authors: Sobia Idrees; Usman A Ashfaq; Natasha Idrees
Journal: Theor Biol Med Model Date: 2013-04-10 Impact factor: 2.432

6. Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints.

Authors: October M Sessions; Andreas Wilm; Uma Sangumathi Kamaraj; Milly M Choy; Angelia Chow; Yuwen Chong; Xin Mei Ong; Niranjan Nagarajan; Alex R Cook; Eng Eong Ooi
Journal: PLoS Negl Trop Dis Date: 2015-09-01

7. Global consensus sequence development and analysis of dengue NS3 conserved domains.

Authors: Ambreen Ayub; Usman A Ashfaq; Sobia Idrees; Asma Haque
Journal: Biores Open Access Date: 2013-10

8. Computer Aided Screening of Phytochemicals from Garcinia against the Dengue NS2B/NS3 Protease.

Authors: Tahir Ul Qamar; Arooj Mumtaz; Usman Ali Ashfaq; Samia Azhar; Tabeer Fatima; Muhammad Hassan; Syed Sajid Hussain; Waheed Akram; Sobia Idrees
Journal: Bioinformation Date: 2014-03-19

9. Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells.

Authors: Xibao Shi; Xiaozhuan Zhang; Yongzhe Chang; Bo Jiang; Ruiguang Deng; Aiping Wang; Gaiping Zhang
Journal: BMC Vet Res Date: 2016-06-06 Impact factor: 2.741

Review 10. Cycluridine: A novel antiviral effective against flaviviruses.

Authors: Angel S Galabov; Lucia Mukova; Yuriy P Abashev; Lilia Wassilewa; Petko Tzvetkov; Vassil Minkov; Igor F Barinskiy; Charles M Rice; Sergey Ouzounov; Dorotea Sidzhakova
Journal: Antivir Chem Chemother Date: 2017-08