Literature DB >> 23619954

Brief report: do the nature of communication impairments in autism spectrum disorders relate to the broader autism phenotype in parents?

Lauren J Taylor1, Murray T Maybery, John Wray, David Ravine, Anna Hunt, Andrew J O Whitehouse.   

Abstract

Extensive empirical evidence indicates that the lesser variant of Autism Spectrum Disorders (ASD) involves a communication impairment that is similar to, but milder than, the deficit in clinical ASD. This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband communication difficulties. ASD probands with at least one BAP parent (identified using the Autism Spectrum Quotient) had greater structural and pragmatic language difficulties (assessed using the Children's Communication Checklist-2) than ASD probands with no BAP parent. This finding provides support for the position that genetic liability for ASD is associated with increased communication difficulties across structural and pragmatic domains.

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Year:  2013        PMID: 23619954     DOI: 10.1007/s10803-013-1838-3

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  31 in total

1.  Narrowing the broader autism phenotype: a study using the Communication Checklist-Adult Version (CC-A).

Authors:  Andrew J O Whitehouse; Hilary Coon; Judith Miller; Bryanna Salisbury; Dorothy V M Bishop
Journal:  Autism       Date:  2010-10-05

2.  Personality and language characteristics in parents from multiple-incidence autism families.

Authors:  J Piven; P Palmer; R Landa; S Santangelo; D Jacobi; D Childress
Journal:  Am J Med Genet       Date:  1997-07-25

3.  Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families.

Authors:  Molly Losh; Debra Childress; Kristen Lam; Joseph Piven
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-06-05       Impact factor: 3.568

4.  Social language use in parents of autistic individuals.

Authors:  R Landa; J Piven; M M Wzorek; J O Gayle; G A Chase; S E Folstein
Journal:  Psychol Med       Date:  1992-02       Impact factor: 7.723

5.  Infantile autism: a genetic study of 21 twin pairs.

Authors:  S Folstein; M Rutter
Journal:  J Child Psychol Psychiatry       Date:  1977-09       Impact factor: 8.982

6.  Subtypes of language disorders in school-age children with autism.

Authors:  Isabelle Rapin; Michelle A Dunn; Michael A Dunn; Doris A Allen; Michael C Stevens; Deborah Fein
Journal:  Dev Neuropsychol       Date:  2009       Impact factor: 2.253

7.  Using a parental checklist to identify diagnostic groups in children with communication impairment: a validation of the Children's Communication Checklist--2.

Authors:  Courtenay Frazier Norbury; Marysia Nash; Gillian Baird; Dorothy Bishop
Journal:  Int J Lang Commun Disord       Date:  2004 Jul-Sep       Impact factor: 3.020

8.  The broader language phenotype of autism: a comparison with specific language impairment.

Authors:  Andrew J O Whitehouse; Johanna G Barry; Dorothy V M Bishop
Journal:  J Child Psychol Psychiatry       Date:  2007-08       Impact factor: 8.982

9.  The broader autism phenotype in simplex and multiplex families.

Authors:  Jennifer A Gerdts; Raphael Bernier; Geraldine Dawson; Annette Estes
Journal:  J Autism Dev Disord       Date:  2013-07

Review 10.  Autism: the phenotype in relatives.

Authors:  A Bailey; S Palferman; L Heavey; A Le Couteur
Journal:  J Autism Dev Disord       Date:  1998-10
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  19 in total

1.  Broader autism phenotype in parents of children with autism: a systematic review of percentage estimates.

Authors:  Eric Rubenstein; Devika Chawla
Journal:  J Child Fam Stud       Date:  2018-02-22

2.  Parental Broad Autism Phenotype and the Language Skills of Children with Autism Spectrum Disorder.

Authors:  Michelle Flippin; Linda R Watson
Journal:  J Autism Dev Disord       Date:  2018-06

3.  Psychometric properties of the Quality of Life Inventory-Disability (QI-Disability) measure.

Authors:  Jenny Downs; Peter Jacoby; Helen Leonard; Amy Epstein; Nada Murphy; Elise Davis; Dinah Reddihough; Andrew Whitehouse; Katrina Williams
Journal:  Qual Life Res       Date:  2018-11-20       Impact factor: 4.147

4.  The association between familial ASD diagnosis, autism symptomatology and developmental functioning in young children.

Authors:  Jasper A Estabillo; Johnny L Matson; Xinrui Jiang
Journal:  Eur Child Adolesc Psychiatry       Date:  2016-03-16       Impact factor: 4.785

5.  Childhood Academic Performance: A Potential Marker of Genetic Liability to Autism.

Authors:  Janna Guilfoyle; Molly Winston; John Sideris; Gary E Martin; Kritika Nayar; Lauren Bush; Tom Wassink; Molly Losh
Journal:  J Autism Dev Disord       Date:  2022-02-23

6.  Child, Maternal and Demographic Factors Influencing Caregiver-Reported Autistic Trait Symptomatology in Toddlers.

Authors:  D A Goh; D Gan; J Kung; S Baron-Cohen; C Allison; H Chen; S M Saw; Y S Chong; V S Rajadurai; K H Tan; P C L Shek; F Yap; B F P Broekman; I Magiati
Journal:  J Autism Dev Disord       Date:  2018-04

Review 7.  Applying the Vulnerability Stress Adaptation Model of Marriage to Couples Raising an Autistic Child: A Call for Research on Adaptive Processes.

Authors:  Hillary K Schiltz; Amy Vaughan Van Hecke
Journal:  Clin Child Fam Psychol Rev       Date:  2020-10-29

8.  The psychometric properties of the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) as a measure of autistic traits in a community sample of Singaporean infants and toddlers.

Authors:  I Magiati; D A Goh; S J Lim; D Z Q Gan; J C L Leong; C Allison; S Baron-Cohen; A Rifkin-Graboi; B F P Broekman; S-M Saw; Y-S Chong; K Kwek; P D Gluckman; S B Lim; M J Meaney
Journal:  Mol Autism       Date:  2015-06-21       Impact factor: 7.509

9.  A "bottom-up" approach to aetiological research in autism spectrum disorders.

Authors:  Lisa M Unwin; Murray T Maybery; John A Wray; Andrew J O Whitehouse
Journal:  Front Hum Neurosci       Date:  2013-09-19       Impact factor: 3.169

10.  Towards a molecular characterization of autism spectrum disorders: an exome sequencing and systems approach.

Authors:  J Y An; A S Cristino; Q Zhao; J Edson; S M Williams; D Ravine; J Wray; V M Marshall; A Hunt; A J O Whitehouse; C Claudianos
Journal:  Transl Psychiatry       Date:  2014-06-03       Impact factor: 6.222

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