Literature DB >> 23619786

Cancer chromosomes going to POT1.

Sandy Chang1.   

Abstract

Alterations in the single-stranded telomere-binding protein POT1 have recently been identified in chronic lymphocytic leukemia. This discovery provides novel insights into how genomic instability induced by dysfunctional telomeres contributes to tumorigenesis.

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Year:  2013        PMID： 23619786      PMCID： PMC4040961          DOI： 10.1038/ng.2617

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

1.  SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair.

Authors:  Yung C Lam; Shamima Akhter; Peili Gu; Jing Ye; Anaïs Poulet; Marie-Josèphe Giraud-Panis; Susan M Bailey; Eric Gilson; Randy J Legerski; Sandy Chang
Journal:  EMBO J       Date:  2010-06-15       Impact factor: 11.598

2.  Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.

Authors:  Agnel Sfeir; Shaheen Kabir; Megan van Overbeek; Giulia B Celli; Titia de Lange
Journal:  Science       Date:  2010-03-26       Impact factor: 47.728

3.  Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.

Authors:  Dirk Hockemeyer; Jan-Peter Daniels; Hiroyuki Takai; Titia de Lange
Journal:  Cell       Date:  2006-07-14       Impact factor: 41.582

4.  Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.

Authors:  Ling Wu; Asha S Multani; Hua He; Wilfredo Cosme-Blanco; Yu Deng; Jian Min Deng; Olga Bachilo; Sen Pathak; Hedioshi Tahara; Susan M Bailey; Yibin Deng; Richard R Behringer; Sandy Chang
Journal:  Cell       Date:  2006-07-14       Impact factor: 41.582

Review 5.  From pathogenesis to treatment of chronic lymphocytic leukaemia.

Authors:  Thorsten Zenz; Daniel Mertens; Ralf Küppers; Hartmut Döhner; Stephan Stilgenbauer
Journal:  Nat Rev Cancer       Date:  2009-12-03       Impact factor: 60.716

Review 6.  Connecting chromosomes, crisis, and cancer.

Authors:  Richard S Maser; Ronald A DePinho
Journal:  Science       Date:  2002-07-26       Impact factor: 47.728

Review 7.  How shelterin protects mammalian telomeres.

Authors:  Wilhelm Palm; Titia de Lange
Journal:  Annu Rev Genet       Date:  2008       Impact factor: 16.830

8.  POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia.

Authors:  Andrew J Ramsay; Víctor Quesada; Miguel Foronda; Laura Conde; Alejandra Martínez-Trillos; Neus Villamor; David Rodríguez; Agnieszka Kwarciak; Cecilia Garabaya; Mercedes Gallardo; Mónica López-Guerra; Armando López-Guillermo; Xose S Puente; María A Blasco; Elías Campo; Carlos López-Otín
Journal:  Nat Genet       Date:  2013-03-17       Impact factor: 38.330

9.  The POT1-TPP1 telomere complex is a telomerase processivity factor.

Authors:  Feng Wang; Elaine R Podell; Arthur J Zaug; Yuting Yang; Paul Baciu; Thomas R Cech; Ming Lei
Journal:  Nature       Date:  2007-01-21       Impact factor: 69.504

10.  TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.

Authors:  Huawei Xin; Dan Liu; Ma Wan; Amin Safari; Hyeung Kim; Wen Sun; Matthew S O'Connor; Zhou Songyang
Journal:  Nature       Date:  2007-01-21       Impact factor: 69.504
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  10 in total

Review 1.  Familial risk of melanoma and links with other cancers.

Authors:  Kachiu C Lee; H William Higgins; Abrar A Qureshi
Journal:  Melanoma Manag       Date:  2015-02-25

2.  Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.

Authors:  Marcia Bellon; Christophe Nicot
Journal:  Int J Cancer Oncol       Date:  2015-06-02

3.  POT1 mutation spectrum in tumour types commonly diagnosed among POT1-associated hereditary cancer syndrome families.

Authors:  Erica Shen; Joanne Xiu; Giselle Y Lopez; Rex Bentley; Ali Jalali; Amy B Heimberger; Matthew N Bainbridge; Melissa L Bondy; Kyle M Walsh
Journal:  J Med Genet       Date:  2020-01-14       Impact factor: 6.318

4.  Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes.

Authors:  Andres M Acosta; Lynette M Sholl; Brendan C Dickson; Jesse K McKenney; Jennifer B Gordetsky; Michael R Pins; Adrian Marino-Enriquez; Fei Dong; Adrian M Dubuc; Paola Dal Cin; Christopher D M Fletcher
Journal:  Mod Pathol       Date:  2021-05-13       Impact factor: 7.842

Review 5.  Telomeres: history, health, and hallmarks of aging.

Authors:  Deepavali Chakravarti; Kyle A LaBella; Ronald A DePinho
Journal:  Cell       Date:  2021-01-14       Impact factor: 41.582

6.  Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis.

Authors:  P Gu; Y Wang; K K Bisht; L Wu; L Kukova; E M Smith; Y Xiao; S M Bailey; M Lei; J Nandakumar; S Chang
Journal:  Oncogene       Date:  2016-11-21       Impact factor: 9.867

7.  Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Authors:  Molly Went; Amit Sud; Asta Försti; Britt-Marie Halvarsson; Niels Weinhold; Scott Kimber; Mark van Duin; Gudmar Thorleifsson; Amy Holroyd; David C Johnson; Ni Li; Giulia Orlando; Philip J Law; Mina Ali; Bowang Chen; Jonathan S Mitchell; Daniel F Gudbjartsson; Rowan Kuiper; Owen W Stephens; Uta Bertsch; Peter Broderick; Chiara Campo; Obul R Bandapalli; Hermann Einsele; Walter A Gregory; Urban Gullberg; Jens Hillengass; Per Hoffmann; Graham H Jackson; Karl-Heinz Jöckel; Ellinor Johnsson; Sigurður Y Kristinsson; Ulf-Henrik Mellqvist; Hareth Nahi; Douglas Easton; Paul Pharoah; Alison Dunning; Julian Peto; Federico Canzian; Anthony Swerdlow; Rosalind A Eeles; ZSofia Kote-Jarai; Kenneth Muir; Nora Pashayan; Jolanta Nickel; Markus M Nöthen; Thorunn Rafnar; Fiona M Ross; Miguel Inacio da Silva Filho; Hauke Thomsen; Ingemar Turesson; Annette Vangsted; Niels Frost Andersen; Anders Waage; Brian A Walker; Anna-Karin Wihlborg; Annemiek Broyl; Faith E Davies; Unnur Thorsteinsdottir; Christian Langer; Markus Hansson; Hartmut Goldschmidt; Martin Kaiser; Pieter Sonneveld; Kari Stefansson; Gareth J Morgan; Kari Hemminki; Björn Nilsson; Richard S Houlston
Journal:  Nat Commun       Date:  2018-09-13       Impact factor: 14.919

8.  Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer.

Authors:  Cong Chen; Peili Gu; Jian Wu; Xianyun Chen; Shuangshuang Niu; Hong Sun; Lijie Wu; Na Li; Junhui Peng; Shaohua Shi; Cuiying Fan; Min Huang; Catherine C L Wong; Qingguo Gong; Chandan Kumar-Sinha; Rongguang Zhang; Lajos Pusztai; Rekha Rai; Sandy Chang; Ming Lei
Journal:  Nat Commun       Date:  2017-04-10       Impact factor: 17.694

9.  A Rare CD4-CD8+ Adult T-Cell Leukemia/Lymphoma with Unique Molecular Mutations: A Case Report with Literature Review.

Authors:  Jui Choudhuri; Leah Geiser Roberts; Yan Zhang; Yanhua Wang; Yanan Fang
Journal:  Case Rep Hematol       Date:  2020-10-30

Review 10.  Genetic and Epigenetic Inheritance at Telomeres.

Authors:  Evan H Lister-Shimauchi; Benjamin McCarthy; Michael Lippincott; Shawn Ahmed
Journal:  Epigenomes       Date:  2022-03-16
  10 in total

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