Literature DB >> 23613319

Microenvironmental induced essentiality of autophagy.

Dean C Singleton1, Adrian L Harris.   

Abstract

Angiogenesis inhibitors cause increased hypoxia in tumors and this results in the induction of cytoprotective autophagy. Targeting this adaptation using autophagy inhibitors can overcome resistance to antiangiogenic therapy and enhance the antitumor effects. ©2013 AACR

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Year:  2013        PMID： 23613319      PMCID： PMC4248230          DOI： 10.1158/1078-0432.CCR-13-0634

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  12 in total

Review 1.  Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease.

Authors:  Shom Goel; Andus Hon-Kit Wong; Rakesh K Jain
Journal:  Cold Spring Harb Perspect Med       Date:  2012-03       Impact factor: 6.915

2.  Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma.

Authors:  Yu-Long Hu; Michael DeLay; Arman Jahangiri; Annette M Molinaro; Samuel D Rose; W Shawn Carbonell; Manish K Aghi
Journal:  Cancer Res       Date:  2012-03-23       Impact factor: 12.701

3.  Rapid decrease in delivery of chemotherapy to tumors after anti-VEGF therapy: implications for scheduling of anti-angiogenic drugs.

Authors:  Astrid A M Van der Veldt; Mark Lubberink; Idris Bahce; Maudy Walraven; Michiel P de Boer; Henri N J M Greuter; N Harry Hendrikse; Jonas Eriksson; Albert D Windhorst; Pieter E Postmus; Henk M Verheul; Erik H Serné; Adriaan A Lammertsma; Egbert F Smit
Journal:  Cancer Cell       Date:  2012-01-17       Impact factor: 31.743

4.  VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex.

Authors:  Kan V Lu; Jeffrey P Chang; Christine A Parachoniak; Melissa M Pandika; Manish K Aghi; David Meyronet; Nadezda Isachenko; Shaun D Fouse; Joanna J Phillips; David A Cheresh; Morag Park; Gabriele Bergers
Journal:  Cancer Cell       Date:  2012-07-10       Impact factor: 31.743

5.  Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.

Authors:  Alan McIntyre; Shalini Patiar; Simon Wigfield; Ji-Liang Li; Ioanna Ledaki; Helen Turley; Russell Leek; Cameron Snell; Kevin Gatter; William S Sly; Richard D Vaughan-Jones; Pawel Swietach; Adrian L Harris
Journal:  Clin Cancer Res       Date:  2012-04-12       Impact factor: 12.531

6.  Genetic interactions in cancer progression and treatment.

Authors:  Alan Ashworth; Christopher J Lord; Jorge S Reis-Filho
Journal:  Cell       Date:  2011-04-01       Impact factor: 41.582

7.  Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition.

Authors:  Annamaria Rapisarda; Melinda Hollingshead; Badarch Uranchimeg; Carrie A Bonomi; Suzanne D Borgel; John P Carter; Bradley Gehrs; Mark Raffeld; Robert J Kinders; Ralph Parchment; Miriam R Anver; Robert H Shoemaker; Giovanni Melillo
Journal:  Mol Cancer Ther       Date:  2009-07-07       Impact factor: 6.261

8.  Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy.

Authors:  Muthu Selvakumaran; Ravi K Amaravadi; Irina A Vasilevskaya; Peter J O'Dwyer
Journal:  Clin Cancer Res       Date:  2013-03-05       Impact factor: 12.531

9.  The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

Authors:  Kasper M A Rouschop; Twan van den Beucken; Ludwig Dubois; Hanneke Niessen; Johan Bussink; Kim Savelkouls; Tom Keulers; Hilda Mujcic; Willy Landuyt; Jan Willem Voncken; Philippe Lambin; Albert J van der Kogel; Marianne Koritzinsky; Bradly G Wouters
Journal:  J Clin Invest       Date:  2009-12-14       Impact factor: 14.808

Review 10.  Autophagy and the integrated stress response.

Authors:  Guido Kroemer; Guillermo Mariño; Beth Levine
Journal:  Mol Cell       Date:  2010-10-22       Impact factor: 17.970
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  1 in total

Review 1.  Adaptive response of resistant cancer cells to chemotherapy.

Authors:  Yi-Jye Chern; Isabella T Tai
Journal:  Cancer Biol Med       Date:  2020-12-15       Impact factor: 4.248
  1 in total

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