Literature DB >> 21458666

Genetic interactions in cancer progression and treatment.

Alan Ashworth1, Christopher J Lord, Jorge S Reis-Filho.   

Abstract

As cancer cell genomes are unveiled at a breathtaking pace, the genetic principles at play in cancer are emerging in all their complexity, prompting the assessment of classical genetic interaction models. Here, we discuss the implications of these findings for cancer progression and heterogeneity and for the development of new therapeutic approaches.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2011        PMID： 21458666     DOI： 10.1016/j.cell.2011.03.020

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  165 in total

Review 1.  Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges.

Authors:  Laura E MacConaill; Paul Van Hummelen; Matthew Meyerson; William C Hahn
Journal:  Cancer Discov       Date:  2011-09       Impact factor: 39.397

Review 2.  Pathway perturbations in signaling networks: Linking genotype to phenotype.

Authors:  Yongsheng Li; Daniel J McGrail; Natasha Latysheva; Song Yi; M Madan Babu; Nidhi Sahni
Journal:  Semin Cell Dev Biol       Date:  2018-05-10       Impact factor: 7.727

3.  Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Authors:  Richard Marcotte; Kevin R Brown; Fernando Suarez; Azin Sayad; Konstantina Karamboulas; Paul M Krzyzanowski; Fabrice Sircoulomb; Mauricio Medrano; Yaroslav Fedyshyn; Judice L Y Koh; Dewald van Dyk; Bodhana Fedyshyn; Marianna Luhova; Glauber C Brito; Franco J Vizeacoumar; Frederick S Vizeacoumar; Alessandro Datti; Dahlia Kasimer; Alla Buzina; Patricia Mero; Christine Misquitta; Josee Normand; Maliha Haider; Troy Ketela; Jeffrey L Wrana; Robert Rottapel; Benjamin G Neel; Jason Moffat
Journal:  Cancer Discov       Date:  2011-12-29       Impact factor: 39.397

4.  Homeostatic plasticity fails at the intersection of autism-gene mutations and a novel class of common genetic modifiers.

Authors:  Özgür Genç; Joon-Yong An; Richard D Fetter; Yelena Kulik; Giulia Zunino; Stephan J Sanders; Graeme W Davis
Journal:  Elife       Date:  2020-07-01       Impact factor: 8.140

Review 5.  Adapting to stress - chaperome networks in cancer.

Authors:  Suhasini Joshi; Tai Wang; Thaís L S Araujo; Sahil Sharma; Jeffrey L Brodsky; Gabriela Chiosis
Journal:  Nat Rev Cancer       Date:  2018-09       Impact factor: 60.716

6.  Personalized sequencing and the future of medicine: discovery, diagnosis and defeat of disease.

Authors:  Edward D Esplin; Ling Oei; Michael P Snyder
Journal:  Pharmacogenomics       Date:  2014-11       Impact factor: 2.533

7.  Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma.

Authors:  Roman Reinartz; Shanshan Wang; Sied Kebir; Daniel J Silver; Anja Wieland; Tong Zheng; Marius Küpper; Laurèl Rauschenbach; Rolf Fimmers; Timothy M Shepherd; Daniel Trageser; Andreas Till; Niklas Schäfer; Martin Glas; Axel M Hillmer; Sven Cichon; Amy A Smith; Torsten Pietsch; Ying Liu; Brent A Reynolds; Anthony Yachnis; David W Pincus; Matthias Simon; Oliver Brüstle; Dennis A Steindler; Björn Scheffler
Journal:  Clin Cancer Res       Date:  2016-08-12       Impact factor: 12.531

8.  Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform.

Authors:  Thomas Gonatopoulos-Pournatzis; Michael Aregger; Kevin R Brown; Shaghayegh Farhangmehr; Ulrich Braunschweig; Henry N Ward; Kevin C H Ha; Alexander Weiss; Maximilian Billmann; Tanja Durbic; Chad L Myers; Benjamin J Blencowe; Jason Moffat
Journal:  Nat Biotechnol       Date:  2020-03-16       Impact factor: 54.908

9.  Cancer vulnerabilities unveiled by genomic loss.

Authors:  Deepak Nijhawan; Travis I Zack; Yin Ren; Matthew R Strickland; Rebecca Lamothe; Steven E Schumacher; Aviad Tsherniak; Henrike C Besche; Joseph Rosenbluh; Shyemaa Shehata; Glenn S Cowley; Barbara A Weir; Alfred L Goldberg; Jill P Mesirov; David E Root; Sangeeta N Bhatia; Rameen Beroukhim; William C Hahn
Journal:  Cell       Date:  2012-08-17       Impact factor: 41.582

10.  Microenvironmental induced essentiality of autophagy.

Authors:  Dean C Singleton; Adrian L Harris
Journal:  Clin Cancer Res       Date:  2013-04-23       Impact factor: 12.531
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.