Literature DB >> 23608843

Acute pancreatitis owing to very high triglyceride levels treated with insulin and heparin infusion.

Madan Raj Aryal1, Naba Raj Mainali, Shobhit Gupta, Manoj Singla.   

Abstract

Hypertriglyceridaemia is the third most common cause of acute pancreatitis in the USA. The treatment approach for hypertriglyceridaemia to date has largely been conservative including weight loss, exercise and avoidance of medications that raise triglyceride levels. This approach, however, is not practical in cases of acute pancreatitis due to severely elevated triglycerides. A small number of case reports have been published supporting the treatment of acute pancreatitis due to severely elevated triglyceride levels with insulin and heparin. We report a case of acute pancreatitis in a young woman due to a triglyceride level of 15,215 mg/dl who was successfully treated with insulin and heparin.

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Year:  2013        PMID: 23608843      PMCID: PMC3645636          DOI: 10.1136/bcr-2013-008550

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).

Authors: 
Journal:  JAMA       Date:  2001-05-16       Impact factor: 56.272

2.  Insulin and heparin in treatment of hypertriglyceridemia-induced pancreatitis.

Authors:  Pankaj Jain; Ramesh-Roop Rai; Harsh Udawat; Sandeep Nijhawan; Amit Mathur
Journal:  World J Gastroenterol       Date:  2007-05-14       Impact factor: 5.742

3.  Hypertriglyceridemia-induced acute pancreatitis treated with insulin and heparin.

Authors:  Jennifer D Twilla; Jimmie Mancell
Journal:  Am J Health Syst Pharm       Date:  2012-02-01       Impact factor: 2.637

4.  [Heparin and insulin in the treatment of acute hypertriglyceridemia-induced pancreatitis].

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Journal:  Schweiz Med Wochenschr       Date:  1999-09-04

5.  Rapid reduction of severely elevated serum triglycerides with insulin infusion, gemfibrozil and niacin.

Authors:  Sujani Poonuru; Sumedha R Pathak; Hemender S Vats; Ram D Pathak
Journal:  Clin Med Res       Date:  2010-09-17

6.  Heparin and insulin in the treatment of hypertriglyceridemia-induced severe acute pancreatitis.

Authors:  Hakan Alagözlü; Mehmet Cindoruk; Tarkan Karakan; Selahattin Unal
Journal:  Dig Dis Sci       Date:  2006-05-03       Impact factor: 3.199

Review 7.  Hypertriglyceridemic pancreatitis: presentation and management.

Authors:  Wayne Tsuang; Udayakumar Navaneethan; Luis Ruiz; Joseph B Palascak; Andres Gelrud
Journal:  Am J Gastroenterol       Date:  2009-03-17       Impact factor: 10.864

Review 8.  Severe hypertriglyceridemia and pancreatitis: presentation and management.

Authors:  Nils Ewald; Philip D Hardt; Hans-Ulrich Kloer
Journal:  Curr Opin Lipidol       Date:  2009-12       Impact factor: 4.776

Review 9.  Hypertriglyceridemia: its etiology, effects and treatment.

Authors:  George Yuan; Khalid Z Al-Shali; Robert A Hegele
Journal:  CMAJ       Date:  2007-04-10       Impact factor: 8.262

Review 10.  Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis.

Authors:  I J Goldberg
Journal:  J Lipid Res       Date:  1996-04       Impact factor: 5.922

  10 in total
  6 in total

Review 1.  Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature.

Authors:  Kiran Joglekar; Ben Brannick; Dipen Kadaria; Amik Sodhi
Journal:  Ther Adv Endocrinol Metab       Date:  2017-02-01       Impact factor: 3.565

Review 2.  Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings.

Authors:  Olga Diakoumakou; Georgios Hatzigeorgiou; Nikos Gontoras; Maria Boutsikou; Vana Kolovou; Sophie Mavrogeni; Vassiliki Giannakopoulou; Genovefa D Kolovou
Journal:  Cholesterol       Date:  2014-12-16

3.  Hypertriglyceridemia induced pancreatitis (chylomicronemia syndrome) treated with supportive care.

Authors:  Emin Uysal; Yahya Ayhan Acar; Emel Gökmen; Ahmet Kutur; Hatice Doğan
Journal:  Case Rep Crit Care       Date:  2014-11-23

4.  Hypertriglyceridemic pancreatitis associated with confounding laboratory abnormalities.

Authors:  Stephen Melnick; Salik Nazir; David Gish; Madan Raj Aryal
Journal:  J Community Hosp Intern Med Perspect       Date:  2016-07-06

5.  Assessment of triglyceride and cholesterol in overweight people based on multiple linear regression and artificial intelligence model.

Authors:  Jing Ma; Jiong Yu; Guangshu Hao; Dan Wang; Yanni Sun; Jianxin Lu; Hongcui Cao; Feiyan Lin
Journal:  Lipids Health Dis       Date:  2017-02-20       Impact factor: 3.876

6.  A Rare Case of Acute Pancreatitis Due to Very Severe Hypertriglyceridemia (>10 000 mg/dL) Successfully Resolved With Insulin Therapy Alone: A Case Report and Literature Review.

Authors:  Vijay Gayam; Amrendra Kumar Mandal; Arshpal Gill; Mazin Khalid; Ruby Sangha; Mowyad Khalid; Pavani Garlapati; Bikash Bhattarai
Journal:  J Investig Med High Impact Case Rep       Date:  2018-09-01
  6 in total

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