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Literature DB >> 23593536

Leptomeningeal metastases in breast cancer.

Abstract

Central nervous system (CNS) metastasis from breast cancer may be characterized as either parenchymal brain metastasis (BM) or leptomeningeal (LM) metastasis. BM are much more common (about 80% of all CNS metastases), and have been more extensively studied than LM. CNS metastasis in breast cancer has been associated with reduced overall survival, with the shortest survival generally observed in cases of LM. Here, we review the epidemiology, prognostic factors, diagnostic tools, currently available treatments, and potential future therapies for LM from breast cancer.

Entities: Disease

Keywords: Leptomeningeal metastases; breast cancer; intrathecal chemotherapy

Year: 2013 PMID： 23593536 PMCID： PMC3623833

Source DB: PubMed Journal: Am J Cancer Res ISSN： 2156-6976 Impact factor: 6.166

53 in total

1. Clinical outcome of central nervous system metastases from breast cancer: differences in survival depending on systemic treatment.

Authors: Hee-Jun Kim; Seock-Ah Im; Bhumsuk Keam; Yu-Jung Kim; Sae-Won Han; Tae Min Kim; Do-Youn Oh; Jee Hyun Kim; Se-Hoon Lee; Eui Kyu Chie; Wonshik Han; Dong-Wan Kim; Tae-You Kim; Dong-Young Noh; Dae Seog Heo; In Ae Park; Yung-Jue Bang; Sung Whan Ha
Journal: J Neurooncol Date: 2011-09-22 Impact factor: 4.130

2. The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

Authors: W Boogerd; M J van den Bent; P J Koehler; J J Heimans; J J van der Sande; N K Aaronson; A A M Hart; J Benraadt; Ch J Vecht
Journal: Eur J Cancer Date: 2004-12 Impact factor: 9.162

3. Survival of breast cancer patients with meningeal carcinomatosis.

Authors: H Gauthier; M N Guilhaume; F C Bidard; J Y Pierga; V Girre; P H Cottu; V Laurence; A Livartowski; L Mignot; V Diéras
Journal: Ann Oncol Date: 2010-04-29 Impact factor: 32.976

4. Intrathecal administration of trastuzumab with cytarabine and methotrexate in breast cancer patients with leptomeningeal carcinomatosis.

Authors: Michal Mego; Zuzana Sycova-Mila; Jana Obertova; Jan Rajec; Stefania Liskova; Patrik Palacka; Stefan Porsok; Jozef Mardiak
Journal: Breast Date: 2011-06-23 Impact factor: 4.380

5. Complete response in HER2+ leptomeningeal carcinomatosis from breast cancer with intrathecal trastuzumab.

Authors: Mafalda Oliveira; Sofia Braga; José Luís Passos-Coelho; Ricardo Fonseca; João Oliveira
Journal: Breast Cancer Res Treat Date: 2011-03-03 Impact factor: 4.872

6. Prognostic factors and treatment options in patients with leptomeningeal metastases of different primary tumors: a retrospective analysis.

Authors: Karin Oechsle; Victoria Lange-Brock; Andreas Kruell; Carsten Bokemeyer; Maike de Wit
Journal: J Cancer Res Clin Oncol Date: 2010-03-04 Impact factor: 4.553

7. Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG).

Authors: B C Pestalozzi; D Zahrieh; K N Price; S B Holmberg; J Lindtner; J Collins; D Crivellari; M F Fey; E Murray; O Pagani; E Simoncini; M Castiglione-Gertsch; R D Gelber; A S Coates; A Goldhirsch
Journal: Ann Oncol Date: 2006-04-07 Impact factor: 32.976

8. Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival.

Authors: Elyse E Lower; D Randolph Drosick; Robbin Blau; Lawrence Brennan; William Danneman; Douglas K Hawley
Journal: Clin Breast Cancer Date: 2003-06 Impact factor: 3.225

9. A prospective randomized trial of single-agent versus combination chemotherapy in meningeal carcinomatosis.

Authors: R N Hitchins; D R Bell; R L Woods; J A Levi
Journal: J Clin Oncol Date: 1987-10 Impact factor: 44.544

10. The risk of central nervous system metastases after trastuzumab therapy in patients with breast carcinoma.

Authors: Rose Lai; Chau T Dang; Mark G Malkin; Lauren E Abrey
Journal: Cancer Date: 2004-08-15 Impact factor: 6.860

28 in total

1. Unique genomic profiles obtained from cerebrospinal fluid cell-free DNA of non-small cell lung cancer patients with leptomeningeal metastases.

Authors: Shenpeng Ying; Honggang Ke; Yan Ding; Yanmei Liu; Xiaowan Tang; Dongyong Yang; Min Li; Junjun Liu; Bing Yu; Jianxing Xiang; Xinru Mao; Han Han-Zhang; Wei Hu; Lili Chen
Journal: Cancer Biol Ther Date: 2018-11-05 Impact factor: 4.742

Review 2. Brain metastasis: new opportunities to tackle therapeutic resistance.

Authors: Joan Seoane; Leticia De Mattos-Arruda
Journal: Mol Oncol Date: 2014-06-02 Impact factor: 6.603

3. Efficacy of Liposomal Cytarabine in the Treatment of Leptomeningeal Metastasis of Breast Cancer.

Authors: Elena Laakmann; Isabell Witzel; Volkmar Müller
Journal: Breast Care (Basel) Date: 2017-06-26 Impact factor: 2.860

4. Headache in a young woman: leptomeningeal metastasis as the first presentation of underlying breast malignancy.

Authors: Poornima Mohan; Marilina Antonelou; Ophelia Dadzie; Simon Dubrey
Journal: BMJ Case Rep Date: 2015-05-06

Review 5. Neuro-ophthalmologic complications of neoplastic leptomeningeal disease.

Authors: Gabriella Szatmáry
Journal: Curr Neurol Neurosci Rep Date: 2013-12 Impact factor: 5.081

6. Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.

Authors: Walter Hans Meisen; Samuel Dubin; Steven T Sizemore; Haritha Mathsyaraja; Katie Thies; Norman L Lehman; Peter Boyer; Alena Cristina Jaime-Ramirez; J Bradley Elder; Kimerly Powell; Arnab Chakravarti; Michael C Ostrowski; Balveen Kaur
Journal: Mol Cancer Ther Date: 2014-11-05 Impact factor: 6.261

7. Malignant pleural and pericardial effusions and meningeal infiltrates without other metastases in breast cancer: A case report.

Authors: Xingxing Lv; Jinlan He; Yuan Shen; Hong Zheng
Journal: Mol Clin Oncol Date: 2016-03-02