Literature DB >> 23584314

Management of hemorrhage complicated by novel oral anticoagulants in the emergency department: case report from the northwestern emergency medicine residency.

Amy Kiraly1, Abbie Lyden, Usha Periyanayagam, Jennifer Chan, Peter S Pang.   

Abstract

Anticoagulation has long complicated the care of hemorrhage in the emergency department and other acute care settings. With the advent of novel anticoagulants such as direct thrombin inhibitors and direct factor Xa inhibitors, the absence of any direct antidote for these medications presents new and difficult challenges in the management of hemorrhagic complications in these patients. We present 2 cases of patients with hemorrhagic complications taking novel oral anticoagulants, their management, and outcomes.

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Year:  2013        PMID: 23584314     DOI: 10.1097/MJT.0b013e3182878d18

Source DB:  PubMed          Journal:  Am J Ther        ISSN: 1075-2765            Impact factor:   2.688


  6 in total

Review 1.  Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine.

Authors:  Jennifer A Frontera; John J Lewin; Alejandro A Rabinstein; Imo P Aisiku; Anne W Alexandrov; Aaron M Cook; Gregory J del Zoppo; Monisha A Kumar; Ellinor I B Peerschke; Michael F Stiefel; Jeanne S Teitelbaum; Katja E Wartenberg; Cindy L Zerfoss
Journal:  Neurocrit Care       Date:  2016-02       Impact factor: 3.210

2.  [Traumatic brain injury in anticoagulated patients : Hemostatic therapy for the treatment of intracranial hemorrhage].

Authors:  C Beynon; A W Unterberg
Journal:  Unfallchirurg       Date:  2017-03       Impact factor: 1.000

3.  The Role of FEIBA in Reversing Novel Oral Anticoagulants in Intracerebral Hemorrhage.

Authors:  Jamil R Dibu; Jonathan M Weimer; Christine Ahrens; Edward Manno; Jennifer A Frontera
Journal:  Neurocrit Care       Date:  2016-06       Impact factor: 3.210

Review 4.  Current status of oral anticoagulant reversal strategies: a review.

Authors:  Aranyak Rawal; Devarshi Ardeshna; Sheharyar Minhas; Brandon Cave; Uzoma Ibeguogu; Rami Khouzam
Journal:  Ann Transl Med       Date:  2019-09

5.  The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor.

Authors:  Nina Haagenrud Schultz; Hoa Thi Tuyet Tran; Stine Bjørnsen; Carola Elisabeth Henriksson; Per Morten Sandset; Pål Andre Holme
Journal:  Thromb J       Date:  2017-02-20

6.  The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII in apixaban-treated patients in vitro.

Authors:  Nina H Schultz; Hoa T T Tran; Stine Bjørnsen; Carola E Henriksson; Per M Sandset; Pål A Holme
Journal:  Res Pract Thromb Haemost       Date:  2017-06-20
  6 in total

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