Literature DB >> 23580795

Growth Inhibitory Activity of a Bis-benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and Prism.

Vaishali Vajpayee1, Sun Mi Lee, Joeng Woo Park, Abhishek Dubey, Hyunuk Kim, Timothy R Cook, Peter J Stang, Ki-Whan Chi.   

Abstract

Two new supramolecular coordination complexes (SCCs), were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 μM for MCF7 cells, as determined from MTS assays.

Entities:  

Year:  2013        PMID： 23580795      PMCID： PMC3619444          DOI： 10.1021/om301174s

Source DB:  PubMed          Journal:  Organometallics        ISSN： 0276-7333            Impact factor:   3.876


  30 in total

1.  Luminescent Mesoporous Molecular Materials Based on Neutral Tetrametallic Rectangles We gratefully acknowledge the U.S. National Science Foundation and the National Oceanic and Atmospheric Administration for financial support. Mass spectrometry was provided by the Washington University Mass Spectrometry Resource, an NIH Research Resource (Grant No. P41RR0954), and by the UIUC School of Chemical Science.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-08-18       Impact factor: 15.336

2.  A bibenzimidazole-containing ruthenium(II) complex acting as a cation-driven molecular switch.

Authors:  S Rau; T Büttner; C Temme; M Ruben; H Görls; D Walther; M Duati; S Fanni; J G Vos
Journal:  Inorg Chem       Date:  2000-04-03       Impact factor: 5.165

3.  Evidence for drug release from a metalla-cage delivery vector following cellular internalisation.

Authors:  Olivier Zava; Johan Mattsson; Bruno Therrien; Paul J Dyson
Journal:  Chemistry       Date:  2010-02-01       Impact factor: 5.236

4.  Self-assembled arene-ruthenium-based rectangles for the selective sensing of multi-carboxylate anions.

Authors:  Vaishali Vajpayee; Young Ho Song; Min Hyung Lee; Hyunuk Kim; Ming Wang; Peter J Stang; Ki-Whan Chi
Journal:  Chemistry       Date:  2011-05-24       Impact factor: 5.236

5.  Self-assembled metalla-bowls for selective sensing of multi-carboxylate anions.

Authors:  Anurag Mishra; Vaishali Vajpayee; Hyunuk Kim; Min Hyung Lee; Hyunji Jung; Ming Wang; Peter J Stang; Ki-Whan Chi
Journal:  Dalton Trans       Date:  2011-11-25       Impact factor: 4.390

6.  Anticancer activity of tetracationic arene ruthenium metalla-cycles.

Authors:  Nicolas P E Barry; Fabio Edafe; Bruno Therrien
Journal:  Dalton Trans       Date:  2011-06-09       Impact factor: 4.390

7.  Self-assembled half-sandwich Ir, Rh-based organometallic molecular boxes for reversible trapping of halocarbon molecules.

Authors:  Ying-Feng Han; Yue Fei; Guo-Xin Jin
Journal:  Dalton Trans       Date:  2010-03-16       Impact factor: 4.390

8.  Antiproliferative activity of chelating N,O- and N,N-ruthenium(II) arene functionalised poly(propyleneimine) dendrimer scaffolds.

Authors:  Preshendren Govender; Anna K Renfrew; Catherine M Clavel; Paul J Dyson; Bruno Therrien; Gregory S Smith
Journal:  Dalton Trans       Date:  2010-12-17       Impact factor: 4.390

9.  A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.

Authors:  J Mann; A Baron; Y Opoku-Boahen; E Johansson; G Parkinson; L R Kelland; S Neidle
Journal:  J Med Chem       Date:  2001-01-18       Impact factor: 7.446

10.  Inhibition of cancer cell growth by ruthenium(II) arene complexes.

Authors:  R E Morris; R E Aird; P del S Murdoch; H Chen; J Cummings; N D Hughes; S Parsons; A Parkin; G Boyd; D I Jodrell; P J Sadler
Journal:  J Med Chem       Date:  2001-10-25       Impact factor: 7.446
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  7 in total

1.  Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage.

Authors:  Yao-Rong Zheng; Kogularamanan Suntharalingam; Peter M Bruno; Wei Lin; Weixue Wang; Michael T Hemann; Stephen J Lippard
Journal:  Inorganica Chim Acta       Date:  2016-03-25       Impact factor: 2.545

2.  Biomedical Applications of Metal Organic Polygons and Polyhedra (MOPs).

Authors:  Soumen K Samanta; Lyle Isaacs
Journal:  Coord Chem Rev       Date:  2020-02-19       Impact factor: 22.315

3.  BODIPY based Metal-Organic Macrocycles and Frameworks: Recent Therapeutic Developments.

Authors:  Gajendra Gupta; Yan Sun; Abhishek Das; Peter J Stang; Chang Yeon Lee
Journal:  Coord Chem Rev       Date:  2021-11-22       Impact factor: 22.315

4.  Biomedical and biochemical applications of self-assembled metallacycles and metallacages.

Authors:  Timothy R Cook; Vaishali Vajpayee; Min Hyung Lee; Peter J Stang; Ki-Whan Chi
Journal:  Acc Chem Res       Date:  2013-06-20       Impact factor: 22.384

5.  Synthesis, Molecular Structure and Cytotoxicity of Molecular Materials Based on Water Soluble Half-Sandwich Rh(III) and Ir(III) Tetranuclear Metalla-Cycles.

Authors:  Gajendra Gupta; Benjamin S Murray; Paul J Dyson; Bruno Therrien
Journal:  Materials (Basel)       Date:  2013-11-20       Impact factor: 3.623

6.  Investigation of the biological and anti-cancer properties of ellagic acid-encapsulated nano-sized metalla-cages.

Authors:  Abhishek Dubey; Dae Won Park; Jung Eun Kwon; Yong Joon Jeong; Taegeun Kim; Inhye Kim; Se Chan Kang; Ki-Whan Chi
Journal:  Int J Nanomedicine       Date:  2015-09-02

7.  Preorganized AgI Bimetallic Precursor with Labile Diphosphorus Ligands for a Programmed Synthesis of Organometallic-Organic Hybrid Polymers.

Authors:  Mehdi Elsayed Moussa; Michael Seidl; Gábor Balázs; Manfred Zabel; Alexander V Virovets; Bianca Attenberger; Andrea Schreiner; Manfred Scheer
Journal:  Chemistry       Date:  2017-10-25       Impact factor: 5.236
  7 in total

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