OBJECTIVE: Prolonged ileus-the failure of postoperative ileus to resolve within a few days after major abdominal surgery-leads to significant medical consequences for the patient and costs to the hospital system. The aim of this retrospective analysis of prospectively collected data was to identify independent preoperative and intraoperative risk factors for prolonged ileus in a large consecutive series of patients who had undergone resection for colorectal cancer. METHODS: Patients were drawn from a hospital registry of 2400 consecutive resections over the period 1995-2009. Thirty-four potential predictors of prolonged ileus were analyzed by logistic regression. RESULTS: Prolonged ileus occurred in 14.0% of patients. Statistically significant independent predictors of prolonged ileus were male sex (OR: 1.7, P < 0.001), peripheral vascular disease (OR: 1.8, P < 0.001), respiratory comorbidity (OR: 1.6, P < 0.001), resection at urgent operation (OR: 2.2, P < 0.001), perioperative transfusion (OR: 1.6, P < 0.010), stoma constructed (OR: 1.4, P < 0.001), and operation lasting ≥3 hours (OR: 1.6, P < 0.001). CONCLUSIONS: These features can be used to alert medical and nursing staff to patients likely to experience prolonged ileus after bowel resection so that they can be monitored closely in the postoperative period and available treatments targeted toward them. These features may also be useful in the research context to facilitate the more efficient selection of high-risk patients as subjects in clinical trials of prevention or treatment.
OBJECTIVE: Prolonged ileus-the failure of postoperative ileus to resolve within a few days after major abdominal surgery-leads to significant medical consequences for the patient and costs to the hospital system. The aim of this retrospective analysis of prospectively collected data was to identify independent preoperative and intraoperative risk factors for prolonged ileus in a large consecutive series of patients who had undergone resection for colorectal cancer. METHODS:Patients were drawn from a hospital registry of 2400 consecutive resections over the period 1995-2009. Thirty-four potential predictors of prolonged ileus were analyzed by logistic regression. RESULTS: Prolonged ileus occurred in 14.0% of patients. Statistically significant independent predictors of prolonged ileus were male sex (OR: 1.7, P < 0.001), peripheral vascular disease (OR: 1.8, P < 0.001), respiratory comorbidity (OR: 1.6, P < 0.001), resection at urgent operation (OR: 2.2, P < 0.001), perioperative transfusion (OR: 1.6, P < 0.010), stoma constructed (OR: 1.4, P < 0.001), and operation lasting ≥3 hours (OR: 1.6, P < 0.001). CONCLUSIONS: These features can be used to alert medical and nursing staff to patients likely to experience prolonged ileus after bowel resection so that they can be monitored closely in the postoperative period and available treatments targeted toward them. These features may also be useful in the research context to facilitate the more efficient selection of high-risk patients as subjects in clinical trials of prevention or treatment.
Authors: Sebastiano Biondo; Jordi Miquel; Eloy Espin-Basany; Jose Luis Sanchez; Thomas Golda; Ana Maria Ferrer-Artola; Antonio Codina-Cazador; Ricardo Frago; Esther Kreisler Journal: World J Surg Date: 2016-01 Impact factor: 3.352
Authors: Lise Courtot; Bertrand Le Roy; Ricardo Memeo; Thibault Voron; Nicolas de Angelis; Nicolas Tabchouri; Francesco Brunetti; Anne Berger; Didier Mutter; Johan Gagniere; Ephrem Salamé; Denis Pezet; Mehdi Ouaïssi Journal: Int J Colorectal Dis Date: 2018-05-07 Impact factor: 2.571
Authors: Nourah Alsharqawi; Mohsen Alhashemi; Pepa Kaneva; Gabriele Baldini; Julio F Fiore; Liane S Feldman; Lawrence Lee Journal: Surg Endosc Date: 2019-07-30 Impact factor: 4.584
Authors: Albert M Wolthuis; Gabriele Bislenghi; Maarten Lambrecht; Steffen Fieuws; Anthony de Buck van Overstraeten; Guy Boeckxstaens; André D'Hoore Journal: Int J Colorectal Dis Date: 2017-04-25 Impact factor: 2.571